OBIDOXIME
- CAS No.
- 7683-36-5
- Chemical Name:
- OBIDOXIME
- Synonyms
- 1,1'-Oxybis(methylene)bis[4-(hydroxyiminomethyl)pyridinium];1,1'-[Oxybis(methylene)]bis[4-[(hydroxyimino)methyl]pyridinium]
- CBNumber:
- CB41424795
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- 7683-36-5.mol
| FDA UNII | N6KNE1QA9O |
|---|
OBIDOXIME Chemical Properties,Uses,Production
Originator
Toksobidin,Polfa-Starogard
Manufacturing Process
2 Methods of producing of obidoxime chloride:
1. Into a boiling agitated solution of 2.44 g pyridine-4-aldoxime in 10 ml absolute ethanol is added dropwise during the course of 25 min a solution of 1.14 g bis-chloromethyl ether in 5 ml absolute ethanol. The reaction mixture is then refluxed for 35 min, and then agitated for 5 h at room temperature. The precipitate of bis-[4-hydroxyimino-methyl-pyridinium-(1)-methyl]-ether
Trade dichloride is thoroughly washed with absolute acetone. The yield is 3.5 g which is 98% of the theoretical, and the melting point is 229°C. If convenient, the mother liquor can be reused to make additional product.
2. 12.2 g (0.1 mole) pyridine-4-aldoxime are dissolved with heating in 125 ml chloroform. Within 25 min, 8.5 g (0.075 mole), α,α-dichlorodimethyl ether in 20 ml chloroform are dropped while stirring into the boiling solution. The reaction mixture is heated for another 35 min. After standing for several hours, the precipitate is filtered off, washed with absolute ethanol, acetone and ether and dried at 80°C. Yield: 17.0 g, 95% of the theoretical, and the melting point is 225°C (dec.).
Therapeutic Function
Antidote
OBIDOXIME Preparation Products And Raw materials
OBIDOXIME Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei YoungXin Pharmaceutical Tech Co.,Ltd. | 0714-3999001 17771081808 | 2654977911@qq.com | China | 9899 | 58 |
| Supplier | Advantage |
|---|---|
| Hubei YoungXin Pharmaceutical Tech Co.,Ltd. | 58 |
