CORTISTATIN-8
- CAS No.
- 485803-62-1
- Chemical Name:
- CORTISTATIN-8
- Synonyms
- CORTISTATIN-8;PCFwKTCK(Disulfide bridge 2 - 7);L-Lysinamide, L-prolyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide
- CBNumber:
- CB42455620
- Molecular Formula:
- C47H68N12O9S2
- Molecular Weight:
- 1009.25
- MDL Number:
- MFCD11045146
- MOL File:
- 485803-62-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Cortistatin-8 Asreported | 255032 | 1mg | $480 |
| Cortistatin-8 | KUA80362 | 5mg | $2003.8 |
| Cortistatin-8 | KUA80362 | 10mg | $3206.1 |
| Cortistatin-8 | KUA80362 | 25mg | $6011.5 |
| Cortistatin-8 | KUA80362 | 50mg | $9618 |
| Boiling point | 1451.7±65.0 °C(Predicted) |
|---|---|
| Density | 1.38±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at -20°C |
| solubility | ≥ 100.9mg/mL in DMSO |
| form | Solid |
| pka | 12.56±0.70(Predicted) |
| color | White to off-white |
| Sequence | Pro-Cys-Phe-{d-Trp}-Lys-Thr-Cys-Lys-NH2 (disulfide bridge: Cys2-Cys7) |
CORTISTATIN-8 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 255032 | Cortistatin-8 Asreported | 485803-62-1 | 1mg | $480 | 2026-06-03 | Buy |
| Biosynth | KUA80362 | Cortistatin-8 | 485803-62-1 | 5mg | $2003.8 | 2026-06-04 | Buy |
| Biosynth | KUA80362 | Cortistatin-8 | 485803-62-1 | 10mg | $3206.1 | 2026-06-04 | Buy |
| Biosynth | KUA80362 | Cortistatin-8 | 485803-62-1 | 25mg | $6011.5 | 2026-06-04 | Buy |
| Biosynth | KUA80362 | Cortistatin-8 | 485803-62-1 | 50mg | $9618 | 2026-06-04 | Buy |
CORTISTATIN-8 Chemical Properties,Uses,Production
Uses
Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals[1].
IC 50
GHSR1a
References
[1] F Prodam, et al. Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans. Neuropeptides. 2008 Feb;42(1):89-93. DOI:10.1016/j.npep.2007.09.006
CORTISTATIN-8 Preparation Products And Raw materials
Raw materials
Preparation Products
CORTISTATIN-8 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Nanjing TGpeptide | +86-13347807150 | support@tgpeptide.com | China | 3279 | 58 |
| Changsha MOL Changes Biotechnology Co., Ltd. | +8619375158599 | info@molchanges.com | China | 5218 | 58 |
| LEON (NANJING) BIOTECHNOLOGY CO., LTD. | +8615051830413 | sales.njleonbiotech@gmail.com | China | 5482 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Avantpbc Chemical Tech(Shanghai) Co,Ltd. | 17802107445 | China | 185 | 55 | |
| Nanjing Leon Biological Technology Co., Ltd. | 025-84523390 -127; 17705183659 | sales@njleonbiotech.com | China | 5501 | 55 |
| Nanjing Peptide Biotech Ltd. | 025-58361106-805 15951641583 | zhao.xu@njpeptide.com | China | 9976 | 55 |
| Chengdu Youngshe Chemical Co., Ltd. | +86-17380623303 +86-17380623303; | Caroline@youngshechem.com | China | 4793 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | Eric@peptidego.com | China | 7617 | 58 |
