tert-butyl 3-acetylazetidine-1-carboxylate
- CAS No.
- 870089-49-9
- Chemical Name:
- tert-butyl 3-acetylazetidine-1-carboxylate
- Synonyms
- 1-Boc-3-acetyl-azetidine;1-Boc-3-acetylazetidine - [A10808];2-methylthiazole-16-carboxylic acid;Oxirane, 2-[6-(phenylMethoxy)ethyl]-;TERT-BUTYL 3-ACETYLAZETIDINE-1-CARBOXYLATE;1,1-Dimethylethyl 3-acetyl-1-azetidinecarboxylate;1-Azetidinecarboxylic acid, 3-acetyl-, 1,1-dimethylethyl ester;3-neneneba acetyl azacyclobutane-1-carboxylic acid tert butyl ester
- CBNumber:
- CB42550583
- Molecular Formula:
- C10H17NO3
- Molecular Weight:
- 199.25
- MDL Number:
- MFCD18073441
- MOL File:
- 870089-49-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1-Boc-3-acetylazetidine 99% | OR317307 | 250mg | $21 |
| 1-Boc-3-acetylazetidine 99% | OR317307 | 1g | $56 |
| 1-Boc-3-acetylazetidine 99% | OR317307 | 5g | $211 |
| 1-Boc-3-acetylazetidine 99% | OR317307 | 25g | $765 |
| 1-Boc-3-acetylazetidine 97.0% | A10808 | 1g | $40 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2933998090 |
tert-butyl 3-acetylazetidine-1-carboxylate price More Price(57)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR317307 | 1-Boc-3-acetylazetidine 99% | 870089-49-9 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR317307 | 1-Boc-3-acetylazetidine 99% | 870089-49-9 | 1g | $56 | 2026-06-04 | Buy |
| Apolloscientific | OR317307 | 1-Boc-3-acetylazetidine 99% | 870089-49-9 | 5g | $211 | 2026-06-04 | Buy |
| Apolloscientific | OR317307 | 1-Boc-3-acetylazetidine 99% | 870089-49-9 | 25g | $765 | 2026-06-04 | Buy |
| Synthonix | A10808 | 1-Boc-3-acetylazetidine 97.0% | 870089-49-9 | 1g | $40 | 2026-05-06 | Buy |
tert-butyl 3-acetylazetidine-1-carboxylate Chemical Properties,Uses,Production
Synthesis
820971-67-3
75-16-1
870089-49-9
B. Preparation of tert-butyl 3-acetylazetidine-1-carboxylate (C56). A solution of tert-butyl 3-[methoxy(methyl)carbamoyl]azetidine-1-carboxylate (C55) (27.1 g, 0.111 mol) in tetrahydrofuran (THF) (200 mL) was slowly added dropwise to a mixture of 1.4 M methylmagnesium bromide in a mixture of tetrahydrofuran and toluene (25:75) (99.0 mL, 0.139 mol) for a controlled dropwise time of 40 min while maintaining the reaction temperature at about 0 °C. After the dropwise addition, the reaction mixture was stirred at 10-15°C for 2 hours, followed by continued stirring at room temperature for 1 hour. Upon completion of the reaction, the mixture was cooled to 0 °C and the reaction was quenched with 10% aqueous citric acid (150 mL). The organic phase was separated and the aqueous phase was extracted with ethyl acetate (EtOAc) (2 x 300 mL). The organic phases were combined, washed with saturated aqueous sodium chloride (2×250 mL) and dried over anhydrous sodium sulfate. After filtration, the solvent was removed by concentration under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography (eluent: chloroform) to afford the target compound C56. yield: 20.6 g, 0.10 mol, 93% yield.1H NMR (400 MHz, CDCl3): δ 4.04-4.02 (m, 4H), 3.43-3.35 (m, 1H), 2.16 (s, 3H), 1.42 (s, 9H) .
References
[1] Patent: US2010/190771, 2010, A1. Location in patent: Page/Page column 31-32
[2] Patent: WO2010/131145, 2010, A1. Location in patent: Page/Page column 87
[3] Patent: US2015/361067, 2015, A1. Location in patent: Paragraph 0621
[4] Patent: WO2018/137573, 2018, A1. Location in patent: Page/Page column 65; 66
[5] Patent: WO2014/173289, 2014, A1. Location in patent: Paragraph 0296; 0300; 0301
tert-butyl 3-acetylazetidine-1-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3461 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15083 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
View Lastest Price from tert-butyl 3-acetylazetidine-1-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-17 | tert-butyl 3-acetylazetidine-1-carboxylate
870089-49-9
|
$2.00-6.00 | 1KG | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | ||
 |
2020-01-01 | tert-butyl 3-acetylazetidine-1-carboxylate
870089-49-9
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- tert-butyl 3-acetylazetidine-1-carboxylate
870089-49-9
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
-
- tert-butyl 3-acetylazetidine-1-carboxylate
870089-49-9
- $1.00
- 99%
- Career Henan Chemical Co
