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ChemicalBook >> CAS DataBase List >>2-chloro-5-hydroxyisonicotinaldehyde

2-chloro-5-hydroxyisonicotinaldehyde

CAS No.
1060804-53-6
Chemical Name:
2-chloro-5-hydroxyisonicotinaldehyde
Synonyms
2-chloro-5-hydroxyisonicotinaldehyde;2-CHLORO-5-HYDROXYPYRIDINE-4-CARBALDEHYDE;4-Pyridinecarboxaldehyde, 2-chloro-5-hydroxy-;2-chloro-5-hydroxyisonicotinaldehyde ISO 9001:2015 REACH
CBNumber:
CB42582935
Molecular Formula:
C6H4ClNO2
Molecular Weight:
157.55
MDL Number:
MFCD13189121
MOL File:
1060804-53-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:43
Product description Number Pack Size Price
2-Chloro-5-hydroxyisonicotinaldehyde KSB80453 250mg $332.5
2-Chloro-5-hydroxyisonicotinaldehyde KSB80453 2.5g $1504.5
2-Chloro-5-hydroxyisonicotinaldehyde 98% OR939481 100mg $93
2-Chloro-5-hydroxyisonicotinaldehyde 98% OR939481 250mg $109
2-Chloro-5-hydroxyisonicotinaldehyde 98% OR939481 100mg $93
More product size

2-chloro-5-hydroxyisonicotinaldehyde Properties

Boiling point 353.3±37.0 °C(Predicted)
Density 1.504±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
pka 6.71±0.10(Predicted)
Appearance Yellow to brown Solid

SAFETY

Risk and Safety Statements

HS Code  2933399990

2-chloro-5-hydroxyisonicotinaldehyde price More Price(45)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth KSB80453 2-Chloro-5-hydroxyisonicotinaldehyde 1060804-53-6 250mg $332.5 2026-06-04 Buy
Biosynth KSB80453 2-Chloro-5-hydroxyisonicotinaldehyde 1060804-53-6 2.5g $1504.5 2026-06-04 Buy
Apolloscientific OR939481 2-Chloro-5-hydroxyisonicotinaldehyde 98% 1060804-53-6 100mg $93 2026-06-04 Buy
Apolloscientific OR939481 2-Chloro-5-hydroxyisonicotinaldehyde 98% 1060804-53-6 250mg $109 2026-06-04 Buy
Apolloscientific OR939481 2-Chloro-5-hydroxyisonicotinaldehyde 98% 1060804-53-6 100mg $93 2026-06-04 Buy
Product number Packaging Price Buy
KSB80453 250mg $332.5 Buy
KSB80453 2.5g $1504.5 Buy
OR939481 100mg $93 Buy
OR939481 250mg $109 Buy
OR939481 100mg $93 Buy

2-chloro-5-hydroxyisonicotinaldehyde Chemical Properties,Uses,Production

Synthesis

2-chloro-5-(MethoxyMethoxy)isonicotinaldehyde

1282516-32-8

2-chloro-5-hydroxyisonicotinaldehyde

1060804-53-6

2-Chloro-5-(methoxymethoxy)pyridine-4-carboxaldehyde (12 g, 59.52 mmol, 1.00 eq.) was used as a starting material, which was dissolved in tetrahydrofuran (80 mL) and 3M hydrochloric acid (130 mL) was added. The reaction mixture was stirred at 60°C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted with 5% aqueous sodium carbonate to 7. The organic layer was separated and the aqueous layer was extracted with ethyl acetate (400 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography, the eluent was ethyl acetate/petroleum ether (1:3), to obtain 2-chloro-5-hydroxypyridine-4-carbaldehyde (6g, yield 64%) as a light yellow solid. the TLC detection conditions: petroleum ether/ethyl acetate = 2:1, Rf = 0.3.

References

[1] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 95; 96
[2] Journal of Medicinal Chemistry, 2016, vol. 59, # 18, p. 8345 - 8368

1282516-32-8
1060804-53-6
Synthesis of 2-chloro-5-hydroxyisonicotinaldehyde from 2-chloro-5-(MethoxyMethoxy)isonicotinaldehyde

2-chloro-5-hydroxyisonicotinaldehyde Preparation Products And Raw materials

Global( 58)Suppliers
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Capot Chemical Co.,Ltd.
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Tianjin Xinghan Biotechnology Co., Ltd
+8618698089028 1725517238@qq.com China 2479 58
Aladdin Scientific
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Suzhou ARTK Medchem Co., Ltd.
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ANHUI BYERSEN BIOTECH CO. LTD
+86-15385096007 +86-17755058861 amy@byersenchemical.com China 10000 58
NANJING YINGWEN BIOTECHNOLOGY CO LTD
+8613382787392 sales@aeechem.com China 10002 58

View Lastest Price from 2-chloro-5-hydroxyisonicotinaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-chloro-5-hydroxyisonicotinaldehyde pictures 2025-11-18 2-chloro-5-hydroxyisonicotinaldehyde
1060804-53-6
$1.10 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2-chloro-5-hydroxyisonicotinaldehyde pictures 2019-12-20 2-chloro-5-hydroxyisonicotinaldehyde
1060804-53-6
1g 95%min 20kg/month Nanjing jinheyou Trading Co., Ltd.
2-chloro-5-hydroxyisonicotinaldehyde 2-CHLORO-5-HYDROXYPYRIDINE-4-CARBALDEHYDE 4-Pyridinecarboxaldehyde, 2-chloro-5-hydroxy- 2-chloro-5-hydroxyisonicotinaldehyde ISO 9001:2015 REACH 1060804-53-6
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