N-desMethyl EnzalutaMide
- CAS No.
- 1242137-16-1
- Chemical Name:
- N-desMethyl EnzalutaMide
- Synonyms
- Enzalutamide impurity B;Enzalutamide impurity O;Enzalutamide N-Desmethyl Impurity;CS-1325;D3-EZ-TJXA;D3-EZLA-IM2;N-desmethyl MDV3100;N-desmethyl MDV-3100;N-desmethyl MDV 3100;Enzalutamide Impurity 2
- CBNumber:
- CB42667014
- Molecular Formula:
- C20H14F4N4O2S
- Molecular Weight:
- 450.41
- MDL Number:
- MFCD24386671
- MOL File:
- 1242137-16-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| N-desmethyl Enzalutamide ≥98% | 41025 | 5mg | $98 |
| N-desmethyl Enzalutamide ≥98% | 41025 | 10mg | $148 |
| N-desmethyl Enzalutamide ≥98% | 41025 | 50mg | $588 |
| N-desmethyl Enzalutamide ≥98% | 41025 | 100mg | $1077 |
| 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide Asreported | 161157 | 10mg | $509 |
| More product size | |||
| Melting point | >230oC (dec.) |
|---|---|
| Boiling point | 572.4±60.0 °C(Predicted) |
| Density | 1.55±0.1 g/cm3(Predicted) |
| storage temp. | Amber Vial, Refrigerator |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated) |
| pka | 14.86±0.50(Predicted) |
| form | Solid |
| color | White to Off-White |
| Stability | Light Sensitive |
| InChI | InChI=1S/C20H14F4N4O2S/c1-19(2)17(30)27(11-4-3-10(9-25)14(7-11)20(22,23)24)18(31)28(19)12-5-6-13(16(26)29)15(21)8-12/h3-8H,1-2H3,(H2,26,29) |
| InChIKey | JSFOGZGIBIQRPU-UHFFFAOYSA-N |
| SMILES | C(N)(=O)C1=CC=C(N2C(=S)N(C3=CC=C(C#N)C(C(F)(F)F)=C3)C(=O)C2(C)C)C=C1F |
N-desMethyl EnzalutaMide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 41025 | N-desmethyl Enzalutamide ≥98% | 1242137-16-1 | 5mg | $98 | 2026-04-30 | Buy |
| Cayman Chemical | 41025 | N-desmethyl Enzalutamide ≥98% | 1242137-16-1 | 10mg | $148 | 2026-04-30 | Buy |
| Cayman Chemical | 41025 | N-desmethyl Enzalutamide ≥98% | 1242137-16-1 | 50mg | $588 | 2026-04-30 | Buy |
| Cayman Chemical | 41025 | N-desmethyl Enzalutamide ≥98% | 1242137-16-1 | 100mg | $1077 | 2026-04-30 | Buy |
| Usbiological | 161157 | 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide Asreported | 1242137-16-1 | 10mg | $509 | 2026-06-03 | Buy |
N-desMethyl EnzalutaMide Chemical Properties,Uses,Production
Uses
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.
Uses
N-desMethyl EnzalutaMide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.
Definition
ChEBI: N-desmethylenzalutamide is a benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with ammonia. It has a role as an antineoplastic agent and an androgen antagonist. It is a member of benzamides, an imidazolidinone, a nitrile, a thiocarbonyl compound, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.
in vivo
N-desmethyl Enzalutamide is an active metabolite that is thought to contribute to the clinical effects of Enzalutamide because it demonstrates primary and secondary pharmacodynamics of similar potency to Enzalutamide and circulates at approximately the same plasma concentrations as Enzalutamide. The carboxylic acid metabolite is pharmacologically inactive and circulates at approximately 25 % lower plasma concentrations than Enzalutamide[1].
N-desMethyl EnzalutaMide Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21587 | 55 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
View Lastest Price from N-desMethyl EnzalutaMide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | N-desmethyl Enzalutamide
1242137-16-1
|
$48.00-140.00 | 99.74% | 10g | TargetMol Chemicals Inc. | ||
 |
2023-09-11 | N-desMethyl EnzalutaMide
1242137-16-1
|
$30.00 | 1kg | 99% | 1000t/year | Anhui Ruihan Technology Co., Ltd | |
 |
2023-09-06 | N-desMethyl EnzalutaMide
1242137-16-1
|
1kg | 99.9% | 20tons | Hebei Xinsheng New Material Technology Co., LTD. |
-
- N-desmethyl Enzalutamide
1242137-16-1
- $48.00-140.00
- 99.74%
- TargetMol Chemicals Inc.
-
- N-desMethyl EnzalutaMide
1242137-16-1
- $30.00
- 99%
- Anhui Ruihan Technology Co., Ltd
-
- N-desMethyl EnzalutaMide
1242137-16-1
- 99.9%
- Hebei Xinsheng New Material Technology Co., LTD.
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