tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate
- CAS No.
- 125982-23-2
- Chemical Name:
- tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate
- Synonyms
- tert-butyl N-(6-oxooxan-3-yl)carbamate;(S)-5-(Boc-amino)tetrahydropyran-2-one;tert-butyl N-[(3S)-6-oxotetrahydropyran-3-yl]carbamate;(S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate;tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate;Carbamic acid, N-[(3S)-tetrahydro-6-oxo-2H-pyran-3-yl]-, 1,1-dimethylethyl ester
- CBNumber:
- CB43163672
- Molecular Formula:
- C10H17NO4
- Molecular Weight:
- 215.25
- MDL Number:
- MOL File:
- 125982-23-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | B53237 | 250mg | $77 |
| (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | B53237 | 1g | $90 |
| (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | B53237 | 5g | $320 |
| (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | B53237 | 10g | $630 |
| (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | AA01FS7A | 250mg | $27 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Synthonix | B53237 | (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | 125982-23-2 | 250mg | $77 | 2026-05-06 | Buy |
| Synthonix | B53237 | (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | 125982-23-2 | 1g | $90 | 2026-05-06 | Buy |
| Synthonix | B53237 | (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | 125982-23-2 | 5g | $320 | 2026-05-06 | Buy |
| Synthonix | B53237 | (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | 125982-23-2 | 10g | $630 | 2026-05-06 | Buy |
| aablocks | AA01FS7A | (S)-tert-Butyl (6-oxotetrahydro-2H-pyran-3-yl)carbamate 97% | 125982-23-2 | 250mg | $27 | 2026-05-30 | Buy |
tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate Chemical Properties,Uses,Production
Synthesis
126587-35-7
125982-23-2
Methyl (S)-4-((tert-butoxycarbonyl)amino)-5-hydroxypentanoate (25 g, 0.1 mol, 1.0 eq.) was used as a raw material, which was dissolved in a mixed solvent of toluene (300 mL) and acetic acid (150 mL), and the reaction was heated and refluxed for 5 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature and subsequently concentrated under reduced pressure to remove the solvent. The concentrated residue was placed in an ice bath and the pH was adjusted to 7-8 by slowly adding saturated sodium bicarbonate solution. the aqueous phase was extracted three times with ethyl acetate, and the organic phases were combined, washed with saturated brine and dried over anhydrous sodium sulfate. After filtration, the filtrate was concentrated to give the crude product. The crude product was purified by solvent recrystallization with mixed solvents of ethyl acetate and petroleum ether to afford the target product tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate (8.0 g, 37.2% yield) as a white powder. The product was analyzed by GC-MS and the molecular ion peak was 215.
References
[1] Tetrahedron Letters, 1989, vol. 30, # 29, p. 3803 - 3804
[2] Journal of Organic Chemistry, 1991, vol. 56, # 13, p. 4167 - 4176
[3] Patent: WO2018/67422, 2018, A1. Location in patent: Page/Page column 47; 48
[4] Patent: WO2015/168246, 2015, A1. Location in patent: Page/Page column 64; 75
tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate Preparation Products And Raw materials
Raw materials
Preparation Products
tert-butyl (S)-(6-oxotetrahydro-2H-pyran-3-yl)carbamate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| ENBRIDGE PHARMTECH CO., LTD. | +8613812269233 | tinayang@enbridgepharm.com | China | 306 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618118463618 | sales1@artkmedchem.com | China | 39021 | 58 |
| NANJING YINGWEN BIOTECHNOLOGY CO LTD | +8613382787392 | sales@aeechem.com | China | 10002 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6939 | 55 |
| TaiChem Taizhou Limited | 052386810091 | zcwy9518@yeah.net | China | 3918 | 58 |
