BML-190
- CAS No.
- 2854-32-2
- Chemical Name:
- BML-190
- Synonyms
- IMMA;BML-190;BML-190 ，S2854;BML-190 USP/EP/BP;BML-190;BML 190;BML190;BML-190, 10 mM in DMSO;Indomethacin morpholinamide;INDOMETHACIN MORPHOLINYLAMIDE;BML-190 (Indomethacin morpholinylamide;Indomethacin Morpholinylamide Impurity
- CBNumber:
- CB4328320
- Molecular Formula:
- C23H23ClN2O4
- Molecular Weight:
- 426.89
- MDL Number:
- MFCD01317813
- MOL File:
- 2854-32-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| IMMA ≥98% | 70275 | 5mg | $29 |
| IMMA ≥98% | 70275 | 10mg | $53 |
| IMMA ≥98% | 70275 | 50mg | $215 |
| IMMA ≥98% | 70275 | 100mg | $376 |
| IMMA ≥98% | 70275 | 5mg | $26 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 3 |
| Toxicity | rat,LDLo,oral,40mg/kg (40mg/kg),Bollettino Chimico Farmaceutico. Vol. 114, Pg. 309, 1975. |
BML-190 price More Price(78)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 70275 | IMMA ≥98% | 2854-32-2 | 5mg | $29 | 2026-04-30 | Buy |
| Cayman Chemical | 70275 | IMMA ≥98% | 2854-32-2 | 10mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 70275 | IMMA ≥98% | 2854-32-2 | 50mg | $215 | 2026-04-30 | Buy |
| Cayman Chemical | 70275 | IMMA ≥98% | 2854-32-2 | 100mg | $376 | 2026-04-30 | Buy |
| Cayman Chemical | 70275 | IMMA ≥98% | 2854-32-2 | 5mg | $26 | 2024-03-01 | Buy |
BML-190 Chemical Properties,Uses,Production
Uses
BML-190, is a selective cannabinoid CB2 receptor, and it is also used for treatment of organophosphate and carbamate toxicity.
Definition
ChEBI: 2-[1-[(4-chlorophenyl)-oxomethyl]-5-methoxy-2-methyl-3-indolyl]-1-(4-morpholinyl)ethanone is a N-acylindole.
Biological Activity
Potent and selective CB 2 receptor ligand (K i values are 435 nM and > 2 μ M for CB 2 and CB 1 respectively).
References
[1] new dc, wong yh. bml-190 and am251 act as inverse agonists at the human cannabinoid cb2 receptor: signalling via camp and inositol phosphates. febs lett. 2003 feb 11;536(1-3):157-60. pubmed pmid: 12586356.
[2] chang yh, lee st, lin ww. effects of cannabinoids on lps-stimulated inflammatory mediator release from macrophages: involvement of eicosanoids. j cell biochem. 2001;81(4):715-23. pubmed pmid: 11329626.
[3] klegeris a, bissonnette cj, mcgeer pl. reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type cb2 receptor. br j pharmacol. 2003 jun;139(4):775-86. pubmed pmid: 12813001; pubmed central pmcid: pmc1573900.
[4] scutt a, williamson em. cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via cb2 receptors. calcif tissue int. 2007 jan;80(1):50-9. epub 2007 jan 4. pubmed pmid: 17205329.
[5] zhang l, zhang x, wu p, li h, jin s, zhou x, li y, ye d, chen b, wan j. bml-111, a lipoxin receptor agonist, modulates the immune response and reduces the severity of collagen-induced arthritis. inflamm res. 2008 apr;57(4):157-62. doi: 10. 1007/s00011-007-7141-z. pubmed pmid: 18648754.
[6] zhang q, ma p, cole rb, wang g. in vitro metabolism of indomethacin morpholinylamide (bml-190), an inverse agonist for the peripheral cannabinoid receptor (cb(2)) in rat liver microsomes. eur j pharm sci. 2010 sep 11;41(1):163-72. doi: 10.1016/j.ejps.2010.06.004. epub 2010 jun 11. pubmed pmid: 20542112; pubmed central pmcid: pmc2907062.
BML-190 Preparation Products And Raw materials
Raw materials
Preparation Products
BML-190 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 | sales@myuchem.com | China | 8834 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
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