4-BROMO PHTHALIC ANHYDRUS
- CAS No.
- 86-90-8
- Chemical Name:
- 4-BROMO PHTHALIC ANHYDRUS
- Synonyms
- 5-Bromoisobenzofuran-1,3-dione;4-BROMOPHTHALIC ANHYDRIDE;5-Bromophthalic anhydride;4-BPA;5-Bromo-1,3-isobenzofurandione;4-BrPA;TIMTEC-BB SBB008534;4-Bromophthal Anhydride;4-Bromophtalic Anhydride;5-Bromo-2-Benzofuran-1,3
- CBNumber:
- CB4395052
- Molecular Formula:
- C8H3BrO3
- Molecular Weight:
- 227.01
- MDL Number:
- MFCD00191323
- MOL File:
- 86-90-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 4-Bromophthalic Anhydride >97.0%(GC) | B1693 | 25g | $93 |
| 4-Bromophthalic Anhydride >97.0%(GC) | B1693 | 500g | $1109 |
| 4-Bromophthalic anhydride 98% | OR45117 | 25g | $21 |
| 4-Bromophthalic anhydride 98% | OR45117 | 100g | $45 |
| 4-Bromophthalic anhydride 95% | J92876 | 5g | $12 |
| More product size | |||
| Melting point | 107 °C |
|---|---|
| Boiling point | 301 °C |
| Density | 1.911 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | very soluble in Benzene |
| form | powder to crystal |
| color | White to Almost white |
| InChI | InChI=1S/C8H3BrO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H |
| InChIKey | BCKVHOUUJMYIAN-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=C(Br)C=C2)C(=O)O1 |
| CAS DataBase Reference | 86-90-8(CAS DataBase Reference) |
| FDA UNII | 2D7E8SD3ZF |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| HS Code | 29173990 | |||||||||
| NFPA 704 |
|
4-BROMO PHTHALIC ANHYDRUS price More Price(63)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | B1693 | 4-Bromophthalic Anhydride >97.0%(GC) | 86-90-8 | 25g | $93 | 2026-04-30 | Buy |
| TCI Chemical | B1693 | 4-Bromophthalic Anhydride >97.0%(GC) | 86-90-8 | 500g | $1109 | 2026-04-30 | Buy |
| Apolloscientific | OR45117 | 4-Bromophthalic anhydride 98% | 86-90-8 | 25g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR45117 | 4-Bromophthalic anhydride 98% | 86-90-8 | 100g | $45 | 2026-06-04 | Buy |
| AK Scientific | J92876 | 4-Bromophthalic anhydride 95% | 86-90-8 | 5g | $12 | 2026-06-04 | Buy |
4-BROMO PHTHALIC ANHYDRUS Chemical Properties,Uses,Production
Uses
4-Bromophthalic anhydride is a white or grayish-white crystalline solid at room temperature and pressure. It can be used as an intermediate in organic and biochemical synthesis, and for the derivatization of drug molecules and bioactive molecules. In addition, 4-Bromophthalic anhydride can also be used in the synthesis of dye intermediates and plant growth regulators.
Chemical Properties
off-white to white powder
Synthesis
85-44-9
86-90-8
To a suspension of phthalic anhydride (1) (22 g, 148.5 mmol, 1.0 eq.) in water (150 mL) was slowly added sodium hydroxide (12 g, 300.0 mmol, 2.0 eq.) and pure bromine (8.5 mL, 165.9 mmol, 1.1 eq.). The reaction mixture was stirred at 90 °C for 12 hours. Upon completion of the reaction, the mixture was cooled to 0 °C and filtered to collect a pale yellow solid. After washing the solid with cold water (50 mL), it was dissolved in sulfur dioxide (60 mL) and the mixture was heated to reflux for 5 hours. The reaction mixture was concentrated and dichloromethane (200 mL) was added to the residue and stirred at room temperature for 2 hours. After filtration, the filtrate was concentrated to give 5-bromoisobenzofuran-1,3-dione (2) (20 g, 71% yield) as a yellow solid.1H NMR (400 MHz, CDCl3) δ 8.16-8.17 (m, 1H), 8.06-8.07 (m, 1H), 7.89-7.90 (m, 1H).
References
[1] Patent: CN105399712, 2016, A. Location in patent: Paragraph 0025
[2] Patent: US2010/204214, 2010, A1. Location in patent: Page/Page column 109
[3] Journal of Medicinal Chemistry, 2017, vol. 60, # 3, p. 1142 - 1150
[4] Patent: WO2018/95260, 2018, A1. Location in patent: Paragraph 058; 060; 0116
[5] Journal of Medicinal Chemistry, 1993, vol. 36, # 22, p. 3417 - 3423
4-BROMO PHTHALIC ANHYDRUS Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Xingshun New Material Co., Ltd. | +86-0519-86461196 | gxx@xingshengtech.com | China | 552 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3372 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Watson Biotechnology Co.,Ltd | +8618186686046 | sales01@watsonbiotech.cn | China | 5731 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1803 | 55 |
View Lastest Price from 4-BROMO PHTHALIC ANHYDRUS manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-25 | 4-BROMO PHTHALIC ANHYDRUS
86-90-8
|
$10.00 | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-07-22 | 4-Bromophthalic Anhydride
86-90-8
|
1kg | 99% | 20MT | Watson Biotechnology Co.,Ltd | ||
 |
2026-07-09 | 4-BROMO PHTHALIC ANHYDRUS
86-90-8
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd |
-
- 4-BROMO PHTHALIC ANHYDRUS
86-90-8
- $10.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- 4-Bromophthalic Anhydride
86-90-8
- 99%
- Watson Biotechnology Co.,Ltd
-
- 4-BROMO PHTHALIC ANHYDRUS
86-90-8
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
