ChemicalBook >> CAS DataBase List >>5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
- CAS No.
- 154934-97-1
- Chemical Name:
- 5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
- Synonyms
- 5-Ethoxycar;5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE;Ethyl 4-(trifluoroMethyl)-2-hydroxypyriMidine-5-carboxylate;ETHYL 2-HYDROXY-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE;Ethyl 2-hydroxy-4-(trifluoromethyl)-5-pyrimidinecarboxylate;5-Ethoxycarbonyl-4-(trifluoromethyl)-1H-pyrimidin-2-one, tech;5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)-PYRIMIDIN-2-(1H)-ONE TECH;Ethyl 2-hydroxy-4-(trifluoromethyl)-5-pyrimidinecarboxylate , 90+%;ETHYL 2-OXO-4-(TRIFLUOROMETHYL)-1,2-DIHYDROPYRIMIDINE-5-CARBOXYLATE;5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL) -N PYRIMIDIN-2-(1H)-ONE, TECH.
- CBNumber:
- CB4437431
- Molecular Formula:
- C8H7F3N2O3
- Molecular Weight:
- 236.15
- MDL Number:
- MFCD00052077
- MOL File:
- 154934-97-1.mol
Last updated:2026-05-28 03:10:55
| Product description | Number | Pack Size | Price |
| Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 296119 | 2g | $333 |
| Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 296119 | 5g | $476 |
| Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 296119 | 10g | $642 |
| Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 296119 | 25g | $864 |
| Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate | 237590 | 1g | $169 |
| More product size | |||
| Melting point | 165 °C |
|---|---|
| Density | 1.50±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 5.03±0.10(Predicted) |
| Appearance | White to off-white Solid |
| CAS DataBase Reference | 154934-97-1(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H312-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36/37/39-37/39 |
| Hazard Note | Irritant |
| HS Code | 29335990 |
5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE price More Price(61)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 296119 | Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 154934-97-1 | 2g | $333 | 2026-06-03 | Buy |
| Usbiological | 296119 | Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 154934-97-1 | 5g | $476 | 2026-06-03 | Buy |
| Usbiological | 296119 | Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 154934-97-1 | 10g | $642 | 2026-06-03 | Buy |
| Usbiological | 296119 | Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate Asreported | 154934-97-1 | 25g | $864 | 2026-06-03 | Buy |
| Usbiological | 237590 | Ethyl 2-hydroxy-4-(trifluoromethyl)pyrimidine-5-carboxylate | 154934-97-1 | 1g | $169 | 2026-06-03 | Buy |
5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE Chemical Properties,Uses,Production
Chemical Properties
White solid
Synthesis
122-51-0
372-31-6
57-13-6
154934-97-1
Urea (2.9 g, 0.05 mol), ethyl 4,4,4-trifluoro-3-oxobutanoate (8.9 g, 0.05 mol) and triethyl orthoformate (7.9 g, 0.05 mol) were dissolved in ethanol (10 mL) under nitrogen protection. The reaction mixture was heated to 80 °C and maintained at this temperature for 4 hours. Upon completion of the reaction, the mixture was cooled to 20 °C and sodium ethanolate solution (21 wt% ethanol solution, 16.9 g, 0.05 mol) was slowly added with stirring for 15 minutes. After addition, stirring of the reaction mixture was continued for 2 hours. Subsequently, water (75 mL) and acetic acid (2 mL) were added to the reaction system at 20 to 30 °C. The resulting slurry was filtered and the filter cake was washed with water (20 mL) and dried at 45 °C. A final product of 8.2 g (72% yield) of the target product ethyl 2-hydroxy-4-trifluoromethyl-5-pyrimidinecarboxylate was obtained as a white solid.1H NMR (400 MHz, (CD3)2SO): δ = 8.69 (s, 1H), 4.24 (q, J = 7.1 Hz, 2H), 1.28 (t, J = 7.1 Hz, 3H). 13C NMR (100 MHz, (CD3)2SO): δ = 161.4, 158.7 (q, J = 35 Hz), 155.5, 154.7, 119.2 (q, J = 278 Hz), 105.7, 61.3, 13.7.
References
[1] Patent: WO2006/48297, 2006, A1. Location in patent: Page/Page column 5; 6
5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 99)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8828 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14303 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9996 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from 5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
154934-97-1
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-09 | 5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
154934-97-1
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
154934-97-1
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE
154934-97-1
- $1.00
- 99%
- Career Henan Chemical Co
154934-97-1(5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE)Related Search:
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5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)-PYRIMIDIN-2-(1H)-ONE TECH
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5-Ethoxycar
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5-ETHOXYCARBONYL-4-(TRIFLUOROMETHYL)PYRIMIDIN-2(1H)-ONE ISO 9001：2015 REACH
154934-97-1
C8H7F3N2O3
