imidazo[1,2-a]pyridine-6-carboxylic acid
![imidazo[1,2-a]pyridine-6-carboxylic acid Structure](CAS/GIF/139022-25-6.gif)
- CAS No.
- 139022-25-6
- Chemical Name:
- imidazo[1,2-a]pyridine-6-carboxylic acid
- Synonyms
- EOS-60803;Olprinone Impurity 32;Imidazo[1,2-a]pyridine-6-...;6-Carboxyimidazo[1,2-a]pyridine;Imidazo[1,2-a]pyridine-6-carboxylicAci;6-imidazo[2,1-f]pyridinecarboxylic acid;iMidazo[1,2-a]pyridin-6-carboxylic acid;IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID;imidazo[2,1-f]pyridine-6-carboxylic acid;H-iMidazo[1,2-a]pyridin-6-carboxylic acid
- CBNumber:
- CB4460305
- Molecular Formula:
- C8H6N2O2
- Molecular Weight:
- 162.15
- MDL Number:
- MFCD07021498
- MOL File:
- 139022-25-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Imidazo[1,2-a]pyridine-6-carboxylic acid ≥95% | OR6355 | 100mg | $21 |
| Imidazo[1,2-a]pyridine-6-carboxylic acid ≥95% | OR6355 | 1g | $24 |
| Imidazo[1,2-a]pyridine-6-carboxylic acid ≥95% | OR6355 | 5g | $55 |
| Imidazo[1,2-a]pyridine-6-carboxylic acid | 045476 | 10.00g | $64 |
| Imidazo[1,2-a]pyridine-6-carboxylic acid | 045476 | 25.00g | $138 |
| More product size | |||
| Melting point | 250 |
|---|---|
| Density | 1.41 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 0.67±0.41(Predicted) |
| form | Solid |
| color | Pale Beige to Light Beige |
| Stability | Hygroscopic |
| InChI | InChI=1S/C8H6N2O2/c11-8(12)6-1-2-7-9-3-4-10(7)5-6/h1-5H,(H,11,12) |
| InChIKey | ONOJJCTXSDBVSP-UHFFFAOYSA-N |
| SMILES | C12=NC=CN1C=C(C(O)=O)C=C2 |
| UNSPSC Code | 12352106 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-43 | |||||||||
| Safety Statements | 22-26-36/37/39-36/37 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2933599590 | |||||||||
| NFPA 704 |
|
imidazo[1,2-a]pyridine-6-carboxylic acid price More Price(68)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR6355 | Imidazo[1,2-a]pyridine-6-carboxylic acid ≥95% | 139022-25-6 | 100mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR6355 | Imidazo[1,2-a]pyridine-6-carboxylic acid ≥95% | 139022-25-6 | 1g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR6355 | Imidazo[1,2-a]pyridine-6-carboxylic acid ≥95% | 139022-25-6 | 5g | $55 | 2026-06-04 | Buy |
| Matrix Scientific | 045476 | Imidazo[1,2-a]pyridine-6-carboxylic acid | 139022-25-6 | 10.00g | $64 | 2026-05-18 | Buy |
| Matrix Scientific | 045476 | Imidazo[1,2-a]pyridine-6-carboxylic acid | 139022-25-6 | 25.00g | $138 | 2026-05-18 | Buy |
imidazo[1,2-a]pyridine-6-carboxylic acid Chemical Properties,Uses,Production
Uses
Imidazo[1,2-a]pyridine-6-carboxylic acid is a brown solid that should be stored sealed at room temperature and away from light. It is a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.
Synthesis
![IMidazo[1,2-a]pyridine-6-carboxylic acid, hydrochloride](/CAS/GIF/1314777-15-5.gif)
1314777-15-5
![imidazo[1,2-a]pyridine-6-carboxylic acid](/CAS/GIF/139022-25-6.gif)
139022-25-6
Step 2. Imidazo[1,2-a]pyridine-6-carboxylic acid hydrochloride (170 g) was dissolved in water (600 mL) and heated until completely dissolved to form a clarified solution. Subsequently, the pH was adjusted to 5-6 by slowly adding 2 M NaOH aqueous solution. the reaction mixture was cooled to 0 °C in an ice-water bath. The precipitate precipitated was collected by vacuum filtration, washed with ethanol and dried under vacuum to afford the target product imidazo[1,2-a]pyridine-6-carboxylic acid (107.2 g, 77% yield) as a light yellow powder. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6) and mass spectrometry (ESI+): 1H NMR δ 13.76-12.82 (br, 1H), 9.28 (s, 1H), 8.10 (s, 1H), 7.68 (s, 1H), 7.64-7.56 (m, 2H); MS (ESI+) m/z: 163 [M + H]+.
References
[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 130
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 81; 82
[3] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 59; 60
[4] Patent: WO2013/130943, 2013, A1. Location in patent: Paragraph 0181
imidazo[1,2-a]pyridine-6-carboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| CHEMSOON CO.,LTD. | +8613761723174 | sales01@chemsoon.com | China | 1211 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23541 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29093 | 58 |
View Lastest Price from imidazo[1,2-a]pyridine-6-carboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID pictures](/ProductImageEN/2021-10/Small/7639ffe8-d5c8-45e9-a40e-32c4c0804c5c.jpg) |
2025-11-18 | IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID
139022-25-6
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
![Imidazo[1,2-a]pyridine-6-carboxylic acid pictures](/ProductImageEN/2022-01/Small/2ea4c713-31ef-4329-8d7c-4f61607071a9.jpeg) |
2022-01-27 | Imidazo[1,2-a]pyridine-6-carboxylic acid
139022-25-6
|
1KG | 98.5% | 100 tons | Honest Joy Holdings Limited
|
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![IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID pictures](https://img.chemicalbook.com/ProductImageEN/2019-8/Small/749ae852-fb61-4b5b-ba66-8a625c577daa.png) |
2019-08-06 | IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID
139022-25-6
|
$8.80 | 1KG | 97%-99% | 100kg | Career Henan Chemical Co |
-
- IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID
139022-25-6
- $1.10
- 99.00%
- Dideu Industries Group Limited
-
- Imidazo[1,2-a]pyridine-6-carboxylic acid
139022-25-6
- $0.00
- 98.5%
- Honest Joy Holdings Limited
-
- IMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID
139022-25-6
- $8.80
- 97%-99%
- Career Henan Chemical Co
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