3,5-DICHLORO-4-PYRIDINECARBONITRILE
- CAS No.
- 153463-65-1
- Chemical Name:
- 3,5-DICHLORO-4-PYRIDINECARBONITRILE
- Synonyms
- 3,5-DICHLOROISONICOTINONITRILE;4-Cyano-3,5-dichloropyridine;3,5-dichloropyridine-4-carbonitrile;3,5-DICHLORO-4-PYRIDINECARBONITRILE;4-Pyridinecarbonitrile, 3,5-dichloro-;3,5-Dichloro-4-pyridinecarbonitrile 97+%;3,5-
Dichloro- 4- pyridinecarbonitrile;3,5-DICHLORO-4-PYRIDINECARBONITRILE ISO 9001：2015 REACH
- CBNumber:
- CB4716970
- Molecular Formula:
- C6H2Cl2N2
- Molecular Weight:
- 173
- MDL Number:
- MFCD00104651
- MOL File:
- 153463-65-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 3,5-Dichloro-4-pyridinecarbonitrile 97% | 644196 | 1g | $45.6 |
| 3,5-Dichloro-4-pyridinecarbonitrile 97% | 644196 | 5g | $188 |
| 3,5-Dichloro-4-pyridinecarbonitrile >98% | OR315205 | 1g | $21 |
| 3,5-Dichloro-4-pyridinecarbonitrile >98% | OR315205 | 5g | $26 |
| 3,5-Dichloro-4-pyridinecarbonitrile >98% | OR315205 | 25g | $127 |
| Melting point | 115-119 °C (lit.) |
|---|---|
| Boiling point | 266.2±35.0 °C(Predicted) |
| Density | 1.49±0.1 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| pka | -0.84±0.10(Predicted) |
| Appearance | White to light yellow Solid |
| InChI | 1S/C6H2Cl2N2/c7-5-2-10-3-6(8)4(5)1-9/h2-3H |
| InChIKey | MUHBRCUFWMUBNP-UHFFFAOYSA-N |
| SMILES | Clc1cncc(Cl)c1C#N |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H317-H318-H335 |
| Precautionary statements | P261-P264-P280-P301+P310-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 22-37/38-41-43 |
| Safety Statements | 26-36/37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| PackingGroup | Ⅲ |
| HS Code | 2933399990 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 Skin Irrit. 2 Skin Sens. 1 STOT SE 3 |
3,5-DICHLORO-4-PYRIDINECARBONITRILE price More Price(70)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 644196 | 3,5-Dichloro-4-pyridinecarbonitrile 97% | 153463-65-1 | 1g | $45.6 | 2023-01-07 | Buy |
| Sigma-Aldrich | 644196 | 3,5-Dichloro-4-pyridinecarbonitrile 97% | 153463-65-1 | 5g | $188 | 2023-01-07 | Buy |
| Apolloscientific | OR315205 | 3,5-Dichloro-4-pyridinecarbonitrile >98% | 153463-65-1 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR315205 | 3,5-Dichloro-4-pyridinecarbonitrile >98% | 153463-65-1 | 5g | $26 | 2026-06-04 | Buy |
| Apolloscientific | OR315205 | 3,5-Dichloro-4-pyridinecarbonitrile >98% | 153463-65-1 | 25g | $127 | 2026-06-04 | Buy |
3,5-DICHLORO-4-PYRIDINECARBONITRILE Chemical Properties,Uses,Production
Synthesis
136590-83-5
153463-65-1
Example 22A: 3,5-Dichloro-4-pyridinecarboxaldehyde (10.0 g, 57.1 mmol) was mixed with hydroxylamine hydrochloride (5.25 g, 76 mmol), formic acid (50 mL) and sodium bisulfate (5 drops). The mixture was refluxed for 6 hours under nitrogen protection. Upon completion of the reaction, the solvent was removed by vacuum concentration. The resulting solid was dissolved in ether (250 mL), washed sequentially with sodium bicarbonate solution and brine, and the organic phase was dried with magnesium sulfate. After filtration, the organic phase was concentrated and finally recrystallized from hexane to give 8.2 g of the target product, 3,5-dichloroisonicotinonitrile, in 83% yield with a melting point of 114 °C.
References
[1] Patent: EP1270577, 2003, A1
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 23, p. 7374 - 7388
[3] Patent: WO2006/81072, 2006, A1. Location in patent: Page/Page column 17; 37
[4] Heterocycles, 1995, vol. 41, # 4, p. 675 - 688
[5] Patent: US6232320, 2001, B1
3,5-DICHLORO-4-PYRIDINECARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-DICHLORO-4-PYRIDINECARBONITRILE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8618071025641 | eric@witopchemical.com | China | 23541 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 | 1059@dideu.com | China | 9995 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19987 | 58 |
View Lastest Price from 3,5-DICHLORO-4-PYRIDINECARBONITRILE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-25 | 3,5-DICHLORO-4-PYRIDINECARBONITRILE
153463-65-1
|
$1.10 | 1g | 99.0% min | 100 tons min | Shaanxi Dideu Medichem Co. Ltd |
-
- 3,5-DICHLORO-4-PYRIDINECARBONITRILE
153463-65-1
- $1.10
- 99.0% min
- Shaanxi Dideu Medichem Co. Ltd
