(4R)-4-Methyl-2-oxazolidinone
- CAS No.
- 4042-43-7
- Chemical Name:
- (4R)-4-Methyl-2-oxazolidinone
- Synonyms
- (4R)-4-Methyl-2-oxazolidinone;(R)-4-methyl-2-azolealkaneone;2-Oxazolidinone,4-methyl-,(4S)-;2-Oxazolidinone, 4-methyl-, (4R)-;(4R)-4-Methyl-2-oxazolidinone4042-43-7;Benzenepropanoicacid,6-chloro-β-oxo-,methylester
- CBNumber:
- CB4853602
- Molecular Formula:
- C4H7NO2
- Molecular Weight:
- 101.1
- MDL Number:
- MOL File:
- 4042-43-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (R)-4-Methyloxazolidin-2-one 97% | OR938550 | 250mg | $29 |
| (R)-4-Methyloxazolidin-2-one 97% | OR938550 | 1g | $36 |
| (R)-4-Methyloxazolidin-2-one 97% | OR938550 | 5g | $112 |
| (R)-4-Methyloxazolidin-2-one 97% | OR938550 | 250mg | $29 |
| (R)-4-Methyloxazolidin-2-one 97% | OR938550 | 1g | $36 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317-H319 |
| Precautionary statements | P280-P305+P351+P338 |
| HS Code | 2934999090 |
(4R)-4-Methyl-2-oxazolidinone price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR938550 | (R)-4-Methyloxazolidin-2-one 97% | 4042-43-7 | 250mg | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR938550 | (R)-4-Methyloxazolidin-2-one 97% | 4042-43-7 | 1g | $36 | 2026-06-04 | Buy |
| Apolloscientific | OR938550 | (R)-4-Methyloxazolidin-2-one 97% | 4042-43-7 | 5g | $112 | 2026-06-04 | Buy |
| Apolloscientific | OR938550 | (R)-4-Methyloxazolidin-2-one 97% | 4042-43-7 | 250mg | $29 | 2026-06-04 | Buy |
| Apolloscientific | OR938550 | (R)-4-Methyloxazolidin-2-one 97% | 4042-43-7 | 1g | $36 | 2026-06-04 | Buy |
(4R)-4-Methyl-2-oxazolidinone Chemical Properties,Uses,Production
Synthesis
75-44-5
35320-23-1
4042-43-7
D-alaninol (8.65 g, 0.12 mmol) was dissolved in a mixed solvent of toluene and KOH aqueous solution (124 mL, 12.5% aqueous solution, 0.28 mmol) at 0 °C. Phosgene (72.7 mL, 20% toluene solution, 0.14 mmol) was added slowly dropwise, and the dropwise acceleration was controlled to maintain the internal temperature of the reaction system below 5 °C. After the dropwise addition, the reaction was continued to be stirred at 0 °C for 40 min. After completion of the reaction, the reaction mixture was concentrated to dryness under reduced pressure. The crude product was dissolved with industrial methanol, filtered to remove insoluble matter, and the filtrate was concentrated under reduced pressure to obtain the crude product. The crude product was purified by silica gel fast column chromatography (eluent gradient: 40-100% cyclohexane solution of ethyl acetate), and 10.4 g (90% yield) of (R)-4-methyl-2-oxazolidinone was finally obtained as a white solid. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 6.00 (broad single peak, 1H), 4.50 (triple peak, J=6.5 Hz, 1H), 4.07-3.97 (multiple peaks, 1H), 3.95 (double dichotomous peaks, J=7.8,6.2 Hz, 1H), and 1.30 (dichotomous peak, J=6.1 Hz, 3H).
References
[1] Patent: WO2017/1645, 2017, A1. Location in patent: Page/Page column 78; 79
[2] Patent: US2017/2022, 2017, A1. Location in patent: Paragraph 0185-0186
(4R)-4-Methyl-2-oxazolidinone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 17389186172 | 1077@dideu.com | China | 3801 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Blocksynth Pharmaceutical Technology Co.,Ltd | 0086-19817745290; +8619817745290 | bd@blocksynth.com | China | 5973 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Shijizhuang Zhoukun Pharmaceutical Technology Co., LTD | 0311-83784138 18633934202 | zhoukunpharma@163.com | China | 2365 | 58 |
| Nanjing Vital Chemical Co., Ltd. | Please Send Email 18652950785 | chemweiao@163.com | China | 4378 | 65 |
| Doly Chemical CO.,LTD. | 021-34716221 15800796336 | sales@dolypharm.com | China | 292 | 55 |
View Lastest Price from (4R)-4-Methyl-2-oxazolidinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-12 | (4R)-4-Methyl-2-oxazolidinone
4042-43-7
|
$2.00-3.00 | 1KG | 99% | 200000KG | Shaanxi Dideu Medichem Co. Ltd |
-
- (4R)-4-Methyl-2-oxazolidinone
4042-43-7
- $2.00-3.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
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