2,4-Dihydroxy-3-methylbenzaldehyde
- CAS No.
- 6248-20-0
- Chemical Name:
- 2,4-Dihydroxy-3-methylbenzaldehyde
- Synonyms
- Einecs 228-369-5;2,4-Dihydroxy-3-meth;4-Formyl-2-methylresorcinol;4-Dihydroxy-3-methylbenzaldehyde;2,4-Dihydroxy-3-methylbenzaldehyd;4-Hydroxy-3-methylsalicylaldehyde;3-methyl-2,4-dihydroxybenzaldehyde;2,4-dihydroxy-3-methylbenzaldehyde;Benzaldehyde, 2,4-dihydroxy-3-methyl-;2,4-Dihydroxy-3-methylbenzaldehyde in Acetonitrile
- CBNumber:
- CB4855217
- Molecular Formula:
- C8H8O3
- Molecular Weight:
- 152.15
- MDL Number:
- MFCD00156883
- MOL File:
- 6248-20-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Formyl-2-methylresorcinol | TRC-F700845-500MG | 500mg | $109 |
| 4-Formyl-2-methylresorcinol | TRC-F700845-1G | 1g | $148 |
| 4-Formyl-2-methylresorcinol | TRC-F700845-10G | 10g | $784 |
| 2,4-Dihydroxy-3-methylbenzaldehyde >97% | OR52629 | 5g | $21 |
| 2,4-Dihydroxy-3-methylbenzaldehyde >97% | OR52629 | 25g | $94 |
| More product size | |||
| Melting point | 150 °C |
|---|---|
| Boiling point | 345.7±12.0 °C(Predicted) |
| Density | 1.331±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 7.93±0.23(Predicted) |
| color | Light Orange to Light Red |
| InChI | InChI=1S/C8H8O3/c1-5-7(10)3-2-6(4-9)8(5)11/h2-4,10-11H,1H3 |
| InChIKey | AOPMHYFEQDBXPZ-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC=C(O)C(C)=C1O |
| LogP | 1.727 (est) |
| EWG's Food Scores | 1-3 |
| FDA UNII | 8X373W842S |
| EPA Substance Registry System | Benzaldehyde, 2,4-dihydroxy-3-methyl- (6248-20-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332-H315-H319-H335 |
| Precautionary statements | P271-P260-P280 |
| Safety Statements | 24/25 |
| TSCA | TSCA listed |
| HS Code | 29124990 |
2,4-Dihydroxy-3-methylbenzaldehyde price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-F700845-500MG | 4-Formyl-2-methylresorcinol | 6248-20-0 | 500mg | $109 | 2026-06-03 | Buy |
| TRC | TRC-F700845-1G | 4-Formyl-2-methylresorcinol | 6248-20-0 | 1g | $148 | 2026-06-03 | Buy |
| TRC | TRC-F700845-10G | 4-Formyl-2-methylresorcinol | 6248-20-0 | 10g | $784 | 2026-06-03 | Buy |
| Apolloscientific | OR52629 | 2,4-Dihydroxy-3-methylbenzaldehyde >97% | 6248-20-0 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR52629 | 2,4-Dihydroxy-3-methylbenzaldehyde >97% | 6248-20-0 | 25g | $94 | 2026-06-04 | Buy |
2,4-Dihydroxy-3-methylbenzaldehyde Chemical Properties,Uses,Production
Uses
4-Formyl-2-methylresorcinol is a reactant in the synthesis of 3-benzo[b]thiophenecoumarin, with potent anti-proliferative activity against breast cancer cell lines
Synthesis
608-25-3
68-12-2
6248-20-0
The general procedure for the synthesis of 3-methyl-2,4-dihydroxybenzaldehyde from 2,6-dihydroxytoluene and N,N-dimethylformamide was as follows: first, N,N-dimethylformamide (6.2 mL, 80.65 mmol) was mixed with phosphorochloride (8.1 mL, 88.61 mmol), followed by the addition of 2-methylresorcinol (5.0 g, 40.3 mmol ) and ethyl acetate (100 mL). The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction solution was combined with ethyl acetate, the organic phase was dried with anhydrous sodium sulfate, filtered to remove the desiccant, and the filtrate was subsequently concentrated under reduced pressure. Finally, the target product 3-methyl-2,4-dihydroxybenzaldehyde (4.9 g, 79.9% yield) was purified by silica gel column chromatography.
References
[1] Organic and Biomolecular Chemistry, 2005, vol. 3, # 12, p. 2305 - 2309
[2] Chemistry - An Asian Journal, 2010, vol. 5, # 1, p. 130 - 140
[3] Patent: CN106957279, 2017, A. Location in patent: Paragraph 0042; 0049; 0050; 0051
[4] Tetrahedron Letters, 2000, vol. 41, # 11, p. 1741 - 1745
[5] Angewandte Chemie - International Edition, 2017, vol. 56, # 42, p. 12888 - 12891
2,4-Dihydroxy-3-methylbenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1056@dideu.com | China | 3967 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +86-571-86217390; +8618058761490 | info@gihichemicals.com | China | 49897 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 |
View Lastest Price from 2,4-Dihydroxy-3-methylbenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | 2,4-Dihydroxy-3-methylbenzaldehyde
6248-20-0
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- 2,4-Dihydroxy-3-methylbenzaldehyde
6248-20-0
- $1.00
- 99%
- Career Henan Chemical Co
