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ChemicalBook >> CAS DataBase List >>2-(TRIFLUOROMETHYL)NICOTINALDEHYDE

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE

CAS No.
116308-35-1
Chemical Name:
2-(TRIFLUOROMETHYL)NICOTINALDEHYDE
Synonyms
2-(TRIFLUOROMETHYL)NICOTINALDEHYDE;2-(Trifluoromwthyl)nicotinaldehyde;2-trifluoromethyl-3-pyridine formaldehyde;2-Trifluoromethyl-pyridine-3-carbaldehyde;2-(Trifluoromethyl)pyridine-3-carBoxaldehyde;2-(trifluoromethyl)-3-pyridinecarboxaldehyde;3-Pyridinecarboxaldehyde,2-(trifluoromethyl)-
CBNumber:
CB5121825
Molecular Formula:
C7H4F3NO
Molecular Weight:
175.11
MDL Number:
MFCD08234912
MOL File:
116308-35-1.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:41
Product description Number Pack Size Price
2-(Trifluoromethyl)nicotinaldehyde 95% PC3733 250mg $113
2-(Trifluoromethyl)nicotinaldehyde 95% PC3733 1g $294
2-(Trifluoromethyl)nicotinaldehyde 95% PC3733 250mg $113
2-(Trifluoromethyl)nicotinaldehyde 95% PC3733 1g $294
2-(Trifluoromethyl)nicotinaldehyde 95% AS42391 1g $206
More product size

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Properties

Boiling point 207.9±40.0 °C(Predicted)
Density 1.369±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka -1.25±0.22(Predicted)
Appearance Colorless to light yellow Liquid

SAFETY

Risk and Safety Statements

Hazard Codes  T
HS Code  2933399990

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC3733 2-(Trifluoromethyl)nicotinaldehyde 95% 116308-35-1 250mg $113 2026-06-04 Buy
Apolloscientific PC3733 2-(Trifluoromethyl)nicotinaldehyde 95% 116308-35-1 1g $294 2026-06-04 Buy
Apolloscientific PC3733 2-(Trifluoromethyl)nicotinaldehyde 95% 116308-35-1 250mg $113 2026-06-04 Buy
Apolloscientific PC3733 2-(Trifluoromethyl)nicotinaldehyde 95% 116308-35-1 1g $294 2026-06-04 Buy
Activate Scientific AS42391 2-(Trifluoromethyl)nicotinaldehyde 95% 116308-35-1 1g $206 2026-06-04 Buy
Product number Packaging Price Buy
PC3733 250mg $113 Buy
PC3733 1g $294 Buy
PC3733 250mg $113 Buy
PC3733 1g $294 Buy
AS42391 1g $206 Buy

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Chemical Properties,Uses,Production

Synthesis

(2-Trifluoromethyl-pyridin-3-yl)-methanol

131747-57-4

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE

116308-35-1

(2-Trifluoromethyl-pyridin-3-yl)-methanol (0.05 g, 0.28 mmol) was used as starting material and dissolved in anhydrous dichloromethane (10 mL). Subsequently, manganese dioxide (0.7 g, 8.0 mmol) was added to the solution. The reaction mixture was stirred under reflux conditions for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered through diatomaceous earth. The filtrate was concentrated by rotary evaporator to afford the target product 2-(trifluoromethyl)pyridine-3-carboxaldehyde as a yellow oil (0.035 g, 71% yield), which could be used in subsequent steps without further purification. The structure of the product was confirmed by 1H-NMR (400 MHz, CDCl3) and mass spectrometry (ESI+): 1H-NMR δ 10.40 (s, 1H), 8.83 (d, J = 4.7 Hz, 1H), 8.37 (d, J = 8.0 Hz, 1H), 7.63 (dd, J = 8.0 and 4.7 Hz, 1H); MS (ESI+): m/ z (M + H)+ = 176.

References

[1] Chemical and Pharmaceutical Bulletin, 1990, vol. 38, # 9, p. 2446 - 2458
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 17, p. 5352 - 5359
[3] Synthesis, 2005, # 16, p. 2751 - 2757
[4] Patent: WO2012/87519, 2012, A1. Location in patent: Page/Page column 123

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Preparation Products And Raw materials

Global( 90)Suppliers
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View Lastest Price from 2-(TRIFLUOROMETHYL)NICOTINALDEHYDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-(Trifluoromethyl)nicotinaldehyde pictures 2020-01-10 2-(Trifluoromethyl)nicotinaldehyde
116308-35-1
$5.50 1KG 98%min 1kg,10kg,100kg Career Henan Chemical Co

2-(TRIFLUOROMETHYL)NICOTINALDEHYDE Spectrum

2-(Trifluoromwthyl)nicotinaldehyde 2-(TRIFLUOROMETHYL)NICOTINALDEHYDE 2-(Trifluoromethyl)pyridine-3-carBoxaldehyde 2-Trifluoromethyl-pyridine-3-carbaldehyde 3-Pyridinecarboxaldehyde,2-(trifluoromethyl)- 2-(trifluoromethyl)-3-pyridinecarboxaldehyde 2-trifluoromethyl-3-pyridine formaldehyde 116308-35-1 pharmacetical
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