1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI)
- CAS No.
- 57031-66-0
- Chemical Name:
- 1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI)
- Synonyms
- Methyl 1-Methyl-1H-1,2,4-triazole-3-carboxylate;methyl 1-methyl-1,2,4-triazole-3-carboxylate;1-Methyl-1H-[1,2,4]triazole-3-carboxylic acid aMide;1-Methyl-1H-[1,2,4]triazole-3-carboxylicacidmethylester;1H-1,2,4-Triazole-3-carboxylic acid, 1-methyl-, methyl ester;1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI)
- CBNumber:
- CB51274188
- Molecular Formula:
- C5H7N3O2
- Molecular Weight:
- 141.13
- MDL Number:
- MFCD13191558
- MOL File:
- 57031-66-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate 98% | AS32738 | 1g | $59 |
| Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate 98% | AS32738 | 5g | $151 |
| Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate 98% | AS32738 | 25g | $416 |
| Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate | 074900 | 5.00g | $85 |
| Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate | 074900 | 25.00g | $401 |
| Boiling point | 263℃ |
|---|---|
| Density | 1.32 |
| Flash point | 113℃ |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 0.69±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | InChI=1S/C5H7N3O2/c1-8-3-6-4(7-8)5(9)10-2/h3H,1-2H3 |
| InChIKey | NKPPQSVPTZHGMA-UHFFFAOYSA-N |
| SMILES | N1(C)C=NC(C(OC)=O)=N1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H302-H319-H335 |
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362 |
1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI) price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS32738 | Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate 98% | 57031-66-0 | 1g | $59 | 2026-06-04 | Buy |
| Activate Scientific | AS32738 | Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate 98% | 57031-66-0 | 5g | $151 | 2026-06-04 | Buy |
| Activate Scientific | AS32738 | Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate 98% | 57031-66-0 | 25g | $416 | 2026-06-04 | Buy |
| Matrix Scientific | 074900 | Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate | 57031-66-0 | 5.00g | $85 | 2026-05-18 | Buy |
| Matrix Scientific | 074900 | Methyl 1-methyl-1H-[1,2,4]triazole-3-carboxylate | 57031-66-0 | 25.00g | $401 | 2026-05-18 | Buy |
1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI) Chemical Properties,Uses,Production
Synthesis
4928-88-5
74-88-4
57031-66-0
Step A: Preparation of methyl 1-methyl-1H-1,2,4-triazole-3-carboxylate: To a suspension of sodium hydride (60% oil dispersion, 0.346 g, 8.66 mmol) in N,N-dimethylformamide (DMF, 20 mL) under stirring at 0°C under nitrogen protection was slowly added dropwise methyl 1H-1,2,4-triazole-3-carboxylate (1.00 g, a 7.87 mmol) solution in DMF (20 mL). The reaction mixture was continued to be stirred at 0 °C for 1 hour. Subsequently, iodomethane (MeI, 0.982 mL, 15.7 mmol) was added dropwise. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was poured into cold water and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed with saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate=3:1) to afford the target product methyl 1-methyl-1H-1,2,4-triazole-3-carboxylate (0.380 g, 34% yield) as a white solid. Mass spectrum (APCI) m/z = 142.1 (M + H).
References
[1] Chemistry and Biodiversity, 2017, vol. 14, # 12,
[2] Patent: WO2014/78417, 2014, A1. Location in patent: Paragraph 00310
[3] Patent: WO2014/78322, 2014, A1. Location in patent: Paragraph 00430
[4] Patent: WO2014/78325, 2014, A1. Location in patent: Paragraph 00614
[5] Patent: WO2014/78408, 2014, A1. Location in patent: Paragraph 00545
1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI) Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PRISUN PHARMATECH CO.,LTD | +86-021-54326183-8001 +8618917565227 | prisun@prisunpharma.com | China | 215 | 58 |
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Wuhan Boye Science And Technology Development Co., Ltd. | 27-81625225 +8615387090420 | sumihu@boyechemicals.com | CHINA | 215 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 24597 | 58 |
View Lastest Price from 1H-1,2,4-Triazole-3-carboxylicacid,1-methyl-,methylester(9CI) manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-17 | Methyl 1-methyl-1H-1,2,4-triazole-3-carboxylate
57031-66-0
|
$2.20-8.80 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- Methyl 1-methyl-1H-1,2,4-triazole-3-carboxylate
57031-66-0
- $2.20-8.80
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
