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ChemicalBook >> CAS DataBase List >>glaucarubinone

glaucarubinone

CAS No.
1259-86-5
Chemical Name:
glaucarubinone
Synonyms
(+)-Glaucarubinone;glaucarubinone;2,16-Dioxo-11β,20-epoxypicrasa-3-ene-1β,11,12α,15β-tetrol 15-[(2S)-2-hydroxy-2-methylbutanoate];11β,20-Epoxy-1β,11,12α-trihydroxy-15β-[(S)-2-hydroxy-2-methyl-1-oxobutoxy]picras-3-ene-2,16-dione;Picras-3-ene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-15-[(2S)-2-hydroxy-2-methyl-1-oxobutoxy]-, (1β,11β,12α,15β)- (9CI);Butyricacid,2-hydroxy-2-methyl-,4-esterwith1,3ab,4,7,7aa,11,11a,11ba-octahydro-1a,2a,4b,11b-tetrahydroxy-3a,8,11ab-trimethyl-2H-1,11cb-(epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6abH)-dione
CBNumber:
CB51318945
Molecular Formula:
C25H34O10
Molecular Weight:
494.53
MDL Number:
MOL File:
1259-86-5.mol
MSDS File:
SDS
Last updated:2025-04-18 09:51:09
Product description Number Pack Size Price
(+)-Glaucarubinone >98% AA00AGMX 1mg $424
(+)-Glaucarubinone >98% AA00AGMX 5mg $980
(+)-Glaucarubinone 96.46% HY-N10926 1mg $333
(+)-Glaucarubinone 96.46% HY-N10926 5mg $808

glaucarubinone Properties

Melting point 228-230 °C
Boiling point 714.1±60.0 °C(Predicted)
Density 1.44±0.1 g/cm3(Predicted)
pka 11.63±0.70(Predicted)
form Solid
color White to off-white

glaucarubinone price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00AGMX (+)-Glaucarubinone >98% 1259-86-5 1mg $424 2026-05-28 Buy
aablocks AA00AGMX (+)-Glaucarubinone >98% 1259-86-5 5mg $980 2026-05-28 Buy
Arctom HY-N10926 (+)-Glaucarubinone 96.46% 1259-86-5 1mg $333 2026-05-26 Buy
Arctom HY-N10926 (+)-Glaucarubinone 96.46% 1259-86-5 5mg $808 2026-05-26 Buy
Product number Packaging Price Buy
AA00AGMX 1mg $424 Buy
AA00AGMX 5mg $980 Buy
HY-N10926 1mg $333 Buy
HY-N10926 5mg $808 Buy

glaucarubinone Chemical Properties,Uses,Production

Uses

(+)-Glaucarubinone is a potent AP-1 (activator protein-1) inhibitor with an EC50 value of 0.13 μM. (+)-Glaucarubinone shows noncytotoxic[1].

Definition

ChEBI: Glaucarubinone is a quassinoid with formula C25H34O10. It is a natural product isolated from several plant species and exhibits anti-cancer and anti-malarial properties. It has a role as a geroprotector, a plant metabolite, an antineoplastic agent and an antimalarial. It is a carboxylic ester, a quassinoid, an organic heteropentacyclic compound, a tetrol, a secondary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone.

References

[1] Diyabalanage T, et al. Nothospondin, a new AP-1 inhibitory quassinoid from the Cameroonian plant Nothospondias staudtii. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4397-9. DOI:10.1016/j.bmcl.2011.06.044

glaucarubinone Preparation Products And Raw materials

Raw materials

Preparation Products

glaucarubinone Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd
+8617392709771 1097@dideu.com China 3992 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7775 56
Hubei Xinkang Pharmaceutical Chemical Co., Ltd 027-027-59308705 18871579363 1248680011@qq.com China 9279 58
Hubei Qifei Pharmaceutical Chemical Co., Ltd 027-59322506 18071128681 1438082200@qq.com China 9555 58
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 2329783215@qq.com China 12661 58
Wuhan Zhongzhicheng Biotechnology Co., Ltd. 13628624121 13628604890 1205052329@qq.com China 9955 58

View Lastest Price from glaucarubinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
glaucarubinone pictures 2025-12-24 glaucarubinone
1259-86-5
1KG 99.0% 10000KG Shaanxi Dideu Medichem Co. Ltd
2,16-Dioxo-11β,20-epoxypicrasa-3-ene-1β,11,12α,15β-tetrol 15-[(2S)-2-hydroxy-2-methylbutanoate] 11β,20-Epoxy-1β,11,12α-trihydroxy-15β-[(S)-2-hydroxy-2-methyl-1-oxobutoxy]picras-3-ene-2,16-dione glaucarubinone Butyricacid,2-hydroxy-2-methyl-,4-esterwith1,3ab,4,7,7aa,11,11a,11ba-octahydro-1a,2a,4b,11b-tetrahydroxy-3a,8,11ab-trimethyl-2H-1,11cb-(epoxymethano)phenanthro[10,1-bc]pyran-5,10(3H,6abH)-dione Picras-3-ene-2,16-dione, 11,20-epoxy-1,11,12-trihydroxy-15-[(2S)-2-hydroxy-2-methyl-1-oxobutoxy]-, (1β,11β,12α,15β)- (9CI) (+)-Glaucarubinone 1259-86-5 C25H34O10
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