N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
- CAS No.
- 42267-27-6
- Chemical Name:
- N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
- Synonyms
- Lys-NCA;N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride;N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride;L-Lys(TFA)-NCA;Lysine-TFA-NCA;Creatinine Impurity 4;Meloxicam Impurity 25;L-LYS(TFA)-NCA(42267-27-6);e-Trifluoroacetyl-Lysine, NCA;-N-(4-(2,5-Dioxooxazolidin-4-yl)
- CBNumber:
- CB51456876
- Molecular Formula:
- C9H11F3N2O4
- Molecular Weight:
- 268.19
- MDL Number:
- MFCD11046652
- MOL File:
- 42267-27-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide | D5600 | 1G | $36 |
| (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide | D5600 | 5G | $187 |
| N6-Trifluoroacetyl-L-lysine N-carboxyanhydride | 290338 | 500mg | $333 |
| N6-Trifluoroacetyl-L-lysine N-carboxyanhydride | 290338 | 1g | $446 |
| N6-Trifluoroacetyl-L-lysine N-carboxyanhydride | 290338 | 2g | $602 |
| More product size | |||
| Melting point | 92-93℃ (DEC.) |
|---|---|
| Density | 1.377 |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly), Ethyl Acetate (Slightly) |
| pka | 9.27±0.40(Predicted) |
| form | Solid |
| color | White to Off-White |
| optical activity | Consistent with structure |
| InChI | InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1 |
| InChIKey | KWNIHCJDDYRQFW-YFKPBYRVSA-N |
| SMILES | C(NCCCC[C@H]1C(=O)OC(=O)N1)(=O)C(F)(F)F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() ![]() GHS07,GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H318-H335 |
| Precautionary statements | P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362 |
| HS Code | 2933.79.8500 |
| REACH Registrations | Active |
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride price More Price(47)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | D5600 | (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide | 42267-27-6 | 1G | $36 | 2026-04-30 | Buy |
| TCI Chemical | D5600 | (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide | 42267-27-6 | 5G | $187 | 2025-07-31 | Buy |
| Usbiological | 290338 | N6-Trifluoroacetyl-L-lysine N-carboxyanhydride | 42267-27-6 | 500mg | $333 | 2026-06-03 | Buy |
| Usbiological | 290338 | N6-Trifluoroacetyl-L-lysine N-carboxyanhydride | 42267-27-6 | 1g | $446 | 2026-06-03 | Buy |
| Usbiological | 290338 | N6-Trifluoroacetyl-L-lysine N-carboxyanhydride | 42267-27-6 | 2g | $602 | 2026-06-03 | Buy |
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Chemical Properties,Uses,Production
Description
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride is a N6-trifluoroacetylated lysine derivative that is used in the synthesis of peptides. It is a racemic mixture of L and D forms, which is hydrolyzed to form L-glutamic acid, NH4Cl, and CO2. N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride has been shown to be useful in the formation of bonds between amino acids, such as lysine and dipeptides. The compound is also used for the protection of lysine against oxidation during peptide synthesis.
Chemical Properties
White to Off-White Solid
Uses
L-Lys(Tfa)-NCA (N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride) can be used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.
Uses
Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.


N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-86-17392712779 +8617792793228 | 1069@dideu.com | China | 8661 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3009 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| Changzhou Carman Chemical Co., Ltd. | 15061933924 | CHINA | 514 | 58 | |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
View Lastest Price from N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-21 | L-Lys(tfa)-NCA
42267-27-6
|
1kg | 99%+ | 1T | Sichuan HongRi Pharma-Tech Co.,Ltd | ||
![]() |
2026-06-18 | L-Lys(Tfa)-NCA
42267-27-6
|
$1.50 | 1g | 99.0% Min | 10 Tons | Shaanxi Didu New Materials Co. Ltd | |
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2020-01-06 | L-Lys(tfa)-NCA
42267-27-6
|
$1.00 | 10g | 98% | 100kg | Sichuan Jiaying Lai Technology Co.,LTD |
-

- L-Lys(tfa)-NCA
42267-27-6
- 99%+
- Sichuan HongRi Pharma-Tech Co.,Ltd
-

- L-Lys(Tfa)-NCA
42267-27-6
- $1.50
- 99.0% Min
- Shaanxi Didu New Materials Co. Ltd
-

- L-Lys(tfa)-NCA
42267-27-6
- $1.00
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD






