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ChemicalBook >> CAS DataBase List >>N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

CAS No.
42267-27-6
Chemical Name:
N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride
Synonyms
Lys-NCA;N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride;N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride;L-Lys(TFA)-NCA;Lysine-TFA-NCA;Creatinine Impurity 4;Meloxicam Impurity 25;L-LYS(TFA)-NCA(42267-27-6);e-Trifluoroacetyl-Lysine, NCA;-N-(4-(2,5-Dioxooxazolidin-4-yl)
CBNumber:
CB51456876
Molecular Formula:
C9H11F3N2O4
Molecular Weight:
268.19
MDL Number:
MFCD11046652
MOL File:
42267-27-6.mol
MSDS File:
SDS
Last updated:2026-06-19 07:28:27
Product description Number Pack Size Price
(S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide D5600 1G $36
(S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide D5600 5G $187
N6-Trifluoroacetyl-L-lysine N-carboxyanhydride 290338 500mg $333
N6-Trifluoroacetyl-L-lysine N-carboxyanhydride 290338 1g $446
N6-Trifluoroacetyl-L-lysine N-carboxyanhydride 290338 2g $602
More product size

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Properties

Melting point 92-93℃ (DEC.)
Density 1.377
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility DMSO (Slightly), Ethyl Acetate (Slightly)
pka 9.27±0.40(Predicted)
form Solid
color White to Off-White
optical activity Consistent with structure
InChI InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1
InChIKey KWNIHCJDDYRQFW-YFKPBYRVSA-N
SMILES C(NCCCC[C@H]1C(=O)OC(=O)N1)(=O)C(F)(F)F

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)Corrosion (GHS05)
GHS07,GHS05
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
HS Code  2933.79.8500
REACH Registrations Active

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D5600 (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide 42267-27-6 1G $36 2026-04-30 Buy
TCI Chemical D5600 (S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide 42267-27-6 5G $187 2025-07-31 Buy
Usbiological 290338 N6-Trifluoroacetyl-L-lysine N-carboxyanhydride 42267-27-6 500mg $333 2026-06-03 Buy
Usbiological 290338 N6-Trifluoroacetyl-L-lysine N-carboxyanhydride 42267-27-6 1g $446 2026-06-03 Buy
Usbiological 290338 N6-Trifluoroacetyl-L-lysine N-carboxyanhydride 42267-27-6 2g $602 2026-06-03 Buy
Product number Packaging Price Buy
D5600 1G $36 Buy
D5600 5G $187 Buy
290338 500mg $333 Buy
290338 1g $446 Buy
290338 2g $602 Buy

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Chemical Properties,Uses,Production

Description

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride is a N6-trifluoroacetylated lysine derivative that is used in the synthesis of peptides. It is a racemic mixture of L and D forms, which is hydrolyzed to form L-glutamic acid, NH4Cl, and CO2. N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride has been shown to be useful in the formation of bonds between amino acids, such as lysine and dipeptides. The compound is also used for the protection of lysine against oxidation during peptide synthesis.

Chemical Properties

White to Off-White Solid

Uses

L-Lys(Tfa)-NCA (N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride) can be used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.

Uses

Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.

112139-31-8
42267-27-6
Synthesis of N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride from L-Lysine, N2-(chlorocarbonyl)-N6-(trifluoroacetyl)- (9CI)

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 150)Suppliers
Supplier Tel Email Country ProdList Advantage
Fuxin Pharmaceutical
+86-021-021-50872116 +8613122107989 contact@fuxinpharm.com China 9976 58
Shaanxi Didu New Materials Co. Ltd
+86-86-17392712779 +8617792793228 1069@dideu.com China 8661 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3009 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Sichuan Jiaying Lai Technology Co.,LTD
18716376478 ycling@enlaibio.com CHINA 302 58
Changzhou Carman Chemical Co., Ltd.
15061933924 CHINA 514 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49979 58

View Lastest Price from N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Lys(tfa)-NCA pictures 2026-07-21 L-Lys(tfa)-NCA
42267-27-6
1kg 99%+ 1T Sichuan HongRi Pharma-Tech Co.,Ltd
L-Lys(Tfa)-NCA pictures 2026-06-18 L-Lys(Tfa)-NCA
42267-27-6
$1.50 1g 99.0% Min 10 Tons Shaanxi Didu New Materials Co. Ltd
L-Lys(tfa)-NCA pictures 2020-01-06 L-Lys(tfa)-NCA
42267-27-6
$1.00 10g 98% 100kg Sichuan Jiaying Lai Technology Co.,LTD
  • L-Lys(Tfa)-NCA pictures
  • L-Lys(Tfa)-NCA
    42267-27-6
  • $1.50
  • 99.0% Min
  • Shaanxi Didu New Materials Co. Ltd
  • L-Lys(tfa)-NCA pictures
  • L-Lys(tfa)-NCA
    42267-27-6
  • $1.00
  • 98%
  • Sichuan Jiaying Lai Technology Co.,LTD

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Spectrum

N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide e-Trifluoroacetyl-Lysine, NCA N-Trifluoroacetyl-L-lysine N-carboxyanhydride N-(4-(2,5-Dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluoroacetamide (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetaMide N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetaMide AcetaMide,N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro- N-[3-[(4S)-2,5-dioxooxazolidin-4-yl]propyl]-2,2,2-trifluoro-acetaMide N-trifluoroacetyl lysine N-carboxyanhydride 4-[(4S)-2,5-DIOXOOXAZOLIDIN-4-YL]BUTYL]-2,2,2-TRIFLUORO-ACETAMIDE (S)-N-(4-(2,5-Dioxooxazolidin-4-yl)-butyl)-2,2,2-trifluoroacetamide L-Lys(TFA)-NCA -N-(4-(2,5-Dioxooxazolidin-4-yl) L-Lysine-N-Trifluoroacetyl-N-Carboxyanhydride L-LYS(TFA)-NCA(42267-27-6) Lysine-TFA-NCA N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]-2,2,2-trifluoroacetamide Nepsilon-Trifluoroacetyl-Nalpha-carboxy-L-lysine Anhydride Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifl... N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Creatinine Impurity 4 Ne-trifluoroacetyl L-lysine intracyclic anhydride Meloxicam Impurity 25 Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluo Lys-NCA N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride N-(4-(2,5-Dioxooxazolidin-4-yl)butyl)-2,2,2-trifluoroacetamide 42267-27-6 C9H11F3N2O4 AMINOACIDS DERIVATIVES Amino Acids & Derivatives Aromatics Chiral Reagents Heterocycles
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