2,4-DICHLORO-6-FLUOROQUINAZOLINE
- CAS No.
- 134517-57-0
- Chemical Name:
- 2,4-DICHLORO-6-FLUOROQUINAZOLINE
- Synonyms
- 4-dichloro-6-fluoroquinazoline;2,4-Dichloro-6-fluoroquinazolin;2,4-dichloro-6-fluoroquinazoline;Quinazoline, 2,4-dichloro-6-fluoro-;2,4-dichloro-6-fluoroquinazoline 97+%
- CBNumber:
- CB51501961
- Molecular Formula:
- C8H3Cl2FN2
- Molecular Weight:
- 217.03
- MDL Number:
- MFCD09954884
- MOL File:
- 134517-57-0.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2,4-dichloro-6-fluoroquinazoline | FD105538 | 10g | $900 |
| 2,4-dichloro-6-fluoroquinazoline 97% | PC502106 | 250mg | $21 |
| 2,4-dichloro-6-fluoroquinazoline 97% | PC502106 | 1g | $25 |
| 2,4-dichloro-6-fluoroquinazoline 97% | PC502106 | 5g | $119 |
| 2,4-dichloro-6-fluoroquinazoline 97% | PC502106 | 25g | $535 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HazardClass | IRRITANT |
| HS Code | 2933599590 |
2,4-DICHLORO-6-FLUOROQUINAZOLINE price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FD105538 | 2,4-dichloro-6-fluoroquinazoline | 134517-57-0 | 10g | $900 | 2026-06-04 | Buy |
| Apolloscientific | PC502106 | 2,4-dichloro-6-fluoroquinazoline 97% | 134517-57-0 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC502106 | 2,4-dichloro-6-fluoroquinazoline 97% | 134517-57-0 | 1g | $25 | 2026-06-04 | Buy |
| Apolloscientific | PC502106 | 2,4-dichloro-6-fluoroquinazoline 97% | 134517-57-0 | 5g | $119 | 2026-06-04 | Buy |
| Apolloscientific | PC502106 | 2,4-dichloro-6-fluoroquinazoline 97% | 134517-57-0 | 25g | $535 | 2026-06-04 | Buy |
2,4-DICHLORO-6-FLUOROQUINAZOLINE Chemical Properties,Uses,Production
Synthesis
88145-90-8
134517-57-0
(Step 2) Synthesis of 2,4-dichloro-6-fluoroquinazoline: Phosphorus pentachloride (12.5 g, 60.0 mmol) was added to phosphorus trichloride (46.0 mL, 502.5 mmol), followed by the slow addition of 6-fluoroquinazoline-2,4(1H,3H)-dione (3.6 g, 20.0 mmol) under stirring. The reaction mixture was heated to reflux and stirred for 9 hours. After completion of the reaction, the mixture was cooled and the solvent was removed under vacuum. An ice-water mixture (400 mL) was added to the residue and stirring was continued for 0.5 hours. The mixture was extracted with dichloromethane (DCM, 250 mL x 3). The DCM layers were combined, dried with anhydrous sodium sulfate, filtered, and the filtrate was concentrated under vacuum. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate, v/v=30/1) to afford the title compound 2,4-dichloro-6-fluoroquinazoline as a white solid (3.735 g, 86.0% yield). m/z MS (ESI, cationic): 216.9 [M + H]+; 1H NMR (CDCl3, 400 MHz) δ ( ppm): 8.03 (dd, J=9.2 Hz, 4.9 Hz, 1H), 7.86 (dd, J=8.1 Hz, 2.7 Hz, 1H), 7.79-7.73 (m, 1H).
References
[1] Patent: WO2017/12502, 2017, A1. Location in patent: Page/Page column 52
[2] Patent: WO2017/88759, 2017, A1. Location in patent: Paragraph 00214
[3] Patent: CN105949203, 2016, A. Location in patent: Paragraph 0179; 0185; 0186
[4] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 24, p. 7717 - 7727
[5] Journal of Medicinal Chemistry, 2008, vol. 51, # 24, p. 7855 - 7865
2,4-DICHLORO-6-FLUOROQUINAZOLINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| PT CHEM GROUP LIMITED | +86-85511178; | peter68@ptchemgroup.com | China | 35425 | 58 |
View Lastest Price from 2,4-DICHLORO-6-FLUOROQUINAZOLINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-26 | 2,4-DICHLORO-6-FLUOROQUINAZOLINE
134517-57-0
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- 2,4-DICHLORO-6-FLUOROQUINAZOLINE
134517-57-0
- $9.80
- ≥99%
- Career Henan Chemical Co
