ISOTHIAZOLINE 1,1-DIOXIDE
- CAS No.
- 5908-62-3
- Chemical Name:
- ISOTHIAZOLINE 1,1-DIOXIDE
- Synonyms
- IsothiazoL;1,2-thiazolidine 1,1-dioxide;idine 1,1-dioxide;ISOTHIAZOLINE 1,1-DIOXIDE;1,2-thiazolidine-1,1-dione;ISOTHIAZOLINE 1,1-DIOXIDE, 10 mM in DMSO;ISOTHIAZOLINE 1,1 DIOXIDE,ISOTHIAZOLINE 1,1DIOXIDE
- CBNumber:
- CB51502322
- Molecular Formula:
- C3H7NO2S
- Molecular Weight:
- 121.16
- MDL Number:
- MFCD09802220
- MOL File:
- 5908-62-3.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 1,3-Propanesultam ≥95% | CS-W001194 | 100mg | $6 |
| 1,3-Propanesultam ≥95% | CS-W001194 | 250mg | $13 |
| 1,3-Propanesultam ≥95% | CS-W001194 | 1g | $44 |
| 1,3-Propanesultam ≥95% | CS-W001194 | 5g | $142 |
| 1,3-Propanesultam ≥95% | CS-W001194 | 10g | $246 |
| More product size | |||
| Melting point | 145-146 °C |
|---|---|
| Boiling point | 128-132 °C(Press: 0.18 Torr) |
| Density | 1.326±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 11.52±0.20(Predicted) |
| form | liquid |
| color | Colorless to light yellow |
| InChI | InChI=1S/C3H7NO2S/c5-7(6)3-1-2-4-7/h4H,1-3H2 |
| InChIKey | XGYCWCIGCYGQFU-UHFFFAOYSA-N |
| SMILES | S1(=O)(=O)CCCN1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| WGK Germany | 3 |
| HS Code | 2934999090 |
ISOTHIAZOLINE 1,1-DIOXIDE price More Price(76)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-W001194 | 1,3-Propanesultam ≥95% | 5908-62-3 | 100mg | $6 | 2026-06-04 | Buy |
| ChemScene | CS-W001194 | 1,3-Propanesultam ≥95% | 5908-62-3 | 250mg | $13 | 2026-06-04 | Buy |
| ChemScene | CS-W001194 | 1,3-Propanesultam ≥95% | 5908-62-3 | 1g | $44 | 2026-06-04 | Buy |
| ChemScene | CS-W001194 | 1,3-Propanesultam ≥95% | 5908-62-3 | 5g | $142 | 2026-06-04 | Buy |
| ChemScene | CS-W001194 | 1,3-Propanesultam ≥95% | 5908-62-3 | 10g | $246 | 2026-06-04 | Buy |
ISOTHIAZOLINE 1,1-DIOXIDE Chemical Properties,Uses,Production
Uses
Propane Sultam is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors as well as in the preparation of cryptochrome imhibitors as antidiabetic agents.
Synthesis
35578-28-0
5908-62-3
At room temperature, 3-chloropropane-1-sulfonamide (27 g, 170 mmol, 1 eq.) was dissolved in ethanol (250 ml), followed by addition of sodium ethoxide (11.7 g, 170 mmol, 1 eq.). The reaction mixture was heated to reflux for 5 h. After completion of the reaction it was cooled to room temperature and concentrated under reduced pressure. The residual solid was fully extracted with dichloromethane, the organic phases were combined and concentrated under reduced pressure to give 1,1-dioxoisothiazolidine (20 g, 100% yield).
References
[1] Patent: WO2004/50619, 2004, A1. Location in patent: Page 24
[2] Journal of the American Chemical Society, 2015, vol. 137, # 17, p. 5638 - 5641
[3] Journal of Organic Chemistry, 1987, vol. 52, # 11, p. 2162 - 2166
[4] Patent: WO2012/3283, 2012, A1. Location in patent: Page/Page column 206-207
[5] Patent: US2012/316147, 2012, A1. Location in patent: Page/Page column 62-63
ISOTHIAZOLINE 1,1-DIOXIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-13017695106 +86-13676922317 | jiuyitime@fdachem.com | China | 16512 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471; | sales@sarms4muscle.com | China | 10473 | 58 |
View Lastest Price from ISOTHIAZOLINE 1,1-DIOXIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-22 | ISOTHIAZOLINE 1,1-DIOXIDE
5908-62-3
|
$29.00 | 97.90% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-04-17 | 1,3-Propanesultam
5908-62-3
|
$1.60-6.60 | 1kg | 99% | 100kg | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- ISOTHIAZOLINE 1,1-DIOXIDE
5908-62-3
- $29.00
- 97.90%
- TargetMol Chemicals Inc.
-
- 1,3-Propanesultam
5908-62-3
- $1.60-6.60
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
5908-62-3(ISOTHIAZOLINE 1,1-DIOXIDE)Related Search:
1of4
