7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE
![7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE Structure](CAS/20180808/GIF/58347-49-2.gif)
- CAS No.
- 58347-49-2
- Chemical Name:
- 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE
- Synonyms
- 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE;Pyrazolo[1,5-a]pyrimidine, 7-chloro-
- CBNumber:
- CB51517825
- Molecular Formula:
- C6H4ClN3
- Molecular Weight:
- 153.57
- MDL Number:
- MFCD04035684
- MOL File:
- 58347-49-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 295673 | 100mg | $369 |
| 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 295673 | 250mg | $456 |
| 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 295673 | 500mg | $609 |
| 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 295673 | 1g | $814 |
| 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE 95% | SC3201 | 1G | $65 |
| More product size | |||
| Melting point | 96-98℃ |
|---|---|
| Density | 1.51 |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | Powder |
| pka | -0.59±0.40(Predicted) |
| color | Off-white to yellow to pink to brown |
| InChI | InChI=1S/C6H4ClN3/c7-5-1-3-8-6-2-4-9-10(5)6/h1-4H |
| InChIKey | YCZQHXPIKQHABJ-UHFFFAOYSA-N |
| SMILES | C12=CC=NN1C(Cl)=CC=N2 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H314 |
| Precautionary statements | P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P321-P305+P351+P338-P405-P501-P264-P270-P301+P312-P330-P501 |
| HS Code | 2933998090 |
7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 295673 | 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 58347-49-2 | 100mg | $369 | 2026-06-03 | Buy |
| Usbiological | 295673 | 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 58347-49-2 | 250mg | $456 | 2026-06-03 | Buy |
| Usbiological | 295673 | 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 58347-49-2 | 500mg | $609 | 2026-06-03 | Buy |
| Usbiological | 295673 | 7-Chloropyrazolo[1,5-a]pyrimidine Asreported | 58347-49-2 | 1g | $814 | 2026-06-03 | Buy |
| AstaTech | SC3201 | 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE 95% | 58347-49-2 | 1G | $65 | 2026-04-30 | Buy |
7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE Chemical Properties,Uses,Production
Uses
7-Clopizo[1,5-A]pyrimidine is a heterocyclic organic compound that can be used as an organic intermediate.
Synthesis
![4H-PYRAZOLO[1,5-A]PYRIMIDIN-7-ONE](/CAS/GIF/29274-23-5.gif)
29274-23-5
![7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE](/CAS/20180808/GIF/58347-49-2.gif)
58347-49-2
Pyrazolo[1,5-a]pyrimidin-7(4H)-one (0.50 g, 3.70 mmol) was added with phosphorus trichloride (0.88 mL, 9.62 mmol) and diisopropylethylamine (DIEA, 0.13 mL, 0.74 mmol), mixed well and then the reaction was stirred at 90 °C overnight. After completion of the reaction, the reaction mixture was slowly poured into ice water and extracted with dichloromethane, and the extract was washed with brine. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated in vacuum. The crude product was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 9:1) to afford the target compound 7-chloropyrazolo[1,5-a]pyrimidine (83 mg, 71% yield).LRMS (m/z): 154 (M + 1)+.1H NMR (400 MHz, DMSO-d6) δ ppm: 6.93 (d, 1H), 7.43 (d, 1H), 8.37 (d, 1H), 8.37 (d, 1H). 1H), 8.37 (d, 1H), 8.52 (d, 1H).
References
[1] Patent: EP2518071, 2012, A1. Location in patent: Page/Page column 38
[2] Patent: WO2012/146667, 2012, A1. Location in patent: Page/Page column 90
[3] Patent: WO2012/146666, 2012, A1. Location in patent: Page/Page column 160
[4] Patent: WO2007/17678, 2007, A1. Location in patent: Page/Page column 44
[5] Journal of Medicinal Chemistry, 1981, vol. 24, # 5, p. 610 - 613
7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3955 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14303 | 58 |
View Lastest Price from 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![7-Chloropyrazolo[1,5-a]pyriMidine pictures](https://img.chemicalbook.com/ProductImageEN/2020-5/Small/94428527-44cf-4fc0-9bea-b9c33ca4c8a5.jpg) |
2020-05-17 | 7-Chloropyrazolo[1,5-a]pyriMidine
58347-49-2
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
![7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE pictures](https://img.chemicalbook.com/ProductImageEN/2018-8/Small/5c80356e-28ed-46e0-8e40-ef35d7b6a689.png) |
2019-07-06 | 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE
58347-49-2
|
$1.00 | 1KG | 95% | 500kg | Career Henan Chemical Co |
-
- 7-Chloropyrazolo[1,5-a]pyriMidine
58347-49-2
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 7-CHLOROPYRAZOLO[1,5-A]PYRIMIDINE
58347-49-2
- $1.00
- 95%
- Career Henan Chemical Co
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