ChemicalBook >> CAS DataBase List >>rac-Sitagliptin
rac-Sitagliptin
- CAS No.
- 823817-56-7
- Chemical Name:
- rac-Sitagliptin
- Synonyms
- rac-Sitagliptin-d4;7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine;3-aMino-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one;rac-Sitagliptin;Sitagliptin chiral isomer;3-a]pyrazin-7(8H)-yl]-4-(2;rac-SitagliptinSee: S491000;5-trifluorophenyl)-1-butanone;3-Amino-1-[3-(trifluoromethyl)-5;7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazine
- CBNumber:
- CB51564874
- Molecular Formula:
- C16H15F6N5O
- Molecular Weight:
- 407.31
- MDL Number:
- MOL File:
- 823817-56-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-04-24 14:58:44
| Product description | Number | Pack Size | Price |
| rac-Sitagliptin | 020965 | 1mg | $340 |
| Sitagliptin impurity E | FO103288 | 1g | $3850 |
| Sitagliptin impurity E | FO103288 | 2g | $4125 |
| Sitagliptin impurity E | FO103288 | 5g | $4468.75 |
| Sitagliptin impurity E | FO103288 | 10g | $4812.5 |
| More product size | |||
rac-Sitagliptin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 020965 | rac-Sitagliptin | 823817-56-7 | 1mg | $340 | 2026-06-03 | Buy |
| Biosynth | FO103288 | Sitagliptin impurity E | 823817-56-7 | 1g | $3850 | 2026-06-04 | Buy |
| Biosynth | FO103288 | Sitagliptin impurity E | 823817-56-7 | 2g | $4125 | 2026-06-04 | Buy |
| Biosynth | FO103288 | Sitagliptin impurity E | 823817-56-7 | 5g | $4468.75 | 2026-06-04 | Buy |
| Biosynth | FO103288 | Sitagliptin impurity E | 823817-56-7 | 10g | $4812.5 | 2026-06-04 | Buy |
rac-Sitagliptin Chemical Properties,Uses,Production
Chemical Properties
Light Brown Syrup
Uses
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes.
in vivo
In vivo, the ED50 value of sitagliptin phosphate for inhibition of plasma DPP-4 activity is calculated to be 2.3 mg/kg 7 hour postdose and 30 mg/kg 24 hour postdose in freely fed Han-Wistar rats[1].The streptozotocin-induced type 1 diabetes mouse model exhibits elevated DPP-4 levels in the plasma that can be substantially inhibited in mice on an Sitagliptin phosphate diet. This is achieved by a positive effect on the regulation of hyperglycemia, potentially through prolongation of islet graft survival[4].The plasma clearance and volume of distribution of Sitagliptin phosphate are higher in rats (40-48 mL/min/kg, 7-9 L/kg) than in dogs (9 mL/min/kg, 3 L/kg); and its half-life is shorter in rats,2 hours compared with 4 hours in dogs[5].
rac-Sitagliptin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 64)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD | +86-15225627621 +86-13213167925 | jiuyitime@fdachem.com | China | 16511 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
| LUYUNJIA CHEMISTRY XIAMEN LIMITED | +86-592-5360779 +86-13055435203 | China | 5988 | 58 | |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43333 | 58 |
| Xiamen Eagle Chemical Limited Corporation | yiyunchem@163.com | China | 5687 | 58 | |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
View Lastest Price from rac-Sitagliptin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-02 | rac-Sitagliptin
823817-56-7
|
$2.00-6.00 | 1KG | 99% | ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD |
-
- rac-Sitagliptin
823817-56-7
- $2.00-6.00
- 99%
- ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
823817-56-7(rac-Sitagliptin)Related Search:
Sitagliptin phosphate
Methyl 3-acetamido-4-(2,4,5-trifluorophenyl)but-2-enoate
(S)-Sitagliptin Phosphate
Sitagliptin Impurity 34
Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
1,2,4-Triazolo[4,3-a]pyrazine, 7-[3-amino-1-oxo-4-(2,4,5-trifluorophenyl)-2-butenyl]-5,6,7,8-tetrahydro- 3-(trifluoromethyl)-
Sitagliptin Defuoro IMpurity 3
Sitagliptin DeaMino IMpurity 1
(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
Sitagliptin Impurity 1
1of4
7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazine
rac-SitagliptinSee: S491000
3-AMino-1-[3-(trifluoroMethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone
7-[1-Oxo-3-amino-4-(2,4,5-trifluorophenyl)butyl]-3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine
rac-Sitagliptin
1-Butanone,3-amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-
3-Amino-1- [3- (trifluoromethyl) -5,6,7,8-tetrahydro-1,2,4-triazolo [4,3-a] pyrazin-7-yl] -4- (2,4,5-trifluorophenyl) butan-1
3-a]pyrazin-7(8H)-yl]-4-(2
3-Amino-1-[3-(trifluoromethyl)-5
5-trifluorophenyl)-1-butanone
Sitagliptin chiral isomer
rac-Sitagliptin-d4
3-aMino-1-(3-(trifluoroMethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
7-[3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine
823817-56-7
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