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ChemicalBook >> CAS DataBase List >>2-Mercapto-4-methyl-5-thiazoleacetic acid

2-Mercapto-4-methyl-5-thiazoleacetic acid

CAS No.
34272-64-5
Chemical Name:
2-Mercapto-4-methyl-5-thiazoleacetic acid
Synonyms
2-(2-mercapto-4-methylthiazol-5-yl)acetic acid;MMTA;Etaa;MTAA/MMTA;2-Mercapto-4-methyl-;Cefodizime Impurity 1;Cefodizime Impurity A;2-Mercapto-4-Methylthiazol;Cefodizime Side Chain Acid;2-Mercapto-4-Methyl-5-Thiazole
CBNumber:
CB5203286
Molecular Formula:
C6H7NO2S2
Molecular Weight:
189.26
MDL Number:
MFCD01750430
MOL File:
34272-64-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:08:01
Product description Number Pack Size Price
2-Mercapto-4-methyl-5-thiazoleacetic acid 98% 522317 10g $171
(2-Mercapto-4-methyl-5-thiazolyl)acetic Acid >98.0%(GC)(T) M2481 5g $24
(2-Mercapto-4-methyl-5-thiazolyl)acetic Acid >98.0%(GC)(T) M2481 25g $54
2-Mercapto-4-methyl-5-thiazoleacetic acid Asreported 283464 5g $395
2-Mercapto-4-methyl-5-thiazoleacetic acid Asreported 283464 10g $553
More product size

2-Mercapto-4-methyl-5-thiazoleacetic acid Properties

Melting point 207 °C (dec.) (lit.)
Boiling point 363.4±44.0 °C(Predicted)
Density 1.52±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility soluble in DMSO, Methanol
pka 4.09±0.10(Predicted)
form powder to crystal
color White to Light yellow
λmax 320nm(H2O)(lit.)
InChI 1S/C6H7NO2S2/c1-3-4(2-5(8)9)11-6(10)7-3/h2H2,1H3,(H,7,10)(H,8,9)
InChIKey KYBOCQHDFLVQIB-UHFFFAOYSA-N
SMILES Cc1nc(S)sc1CC(O)=O
CAS DataBase Reference 34272-64-5(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN 3335
WGK Germany  3
RTECS  XJ1921000
HS Code  2934.10.2000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
Toxicity mouse,LD50,intravenous,1680mg/kg (1680mg/kg),Therapie. Vol. 26, Pg. 497, 1971.
NFPA 704
0
1 0

2-Mercapto-4-methyl-5-thiazoleacetic acid price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 522317 2-Mercapto-4-methyl-5-thiazoleacetic acid 98% 34272-64-5 10g $171 2026-04-30 Buy
TCI Chemical M2481 (2-Mercapto-4-methyl-5-thiazolyl)acetic Acid >98.0%(GC)(T) 34272-64-5 5g $24 2026-04-30 Buy
TCI Chemical M2481 (2-Mercapto-4-methyl-5-thiazolyl)acetic Acid >98.0%(GC)(T) 34272-64-5 25g $54 2024-03-01 Buy
Usbiological 283464 2-Mercapto-4-methyl-5-thiazoleacetic acid Asreported 34272-64-5 5g $395 2026-06-03 Buy
Usbiological 283464 2-Mercapto-4-methyl-5-thiazoleacetic acid Asreported 34272-64-5 10g $553 2026-06-03 Buy
Product number Packaging Price Buy
522317 10g $171 Buy
M2481 5g $24 Buy
M2481 25g $54 Buy
283464 5g $395 Buy
283464 10g $553 Buy

2-Mercapto-4-methyl-5-thiazoleacetic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

2-Mercapto-4-methyl-5-thiazoleacetic acid may be used as a capping agent in the preparation of fused spherical gold nanoparticles. It may also be used in the synthesis of eight-tin macrocyclic complex (a 40-membered macrocycle containing two distannoxane ladders).

General Description

2-Mercapto-4-methyl-5-thiazoleacetic acid is a thiazole derivative. It participates in the preparation of dinuclear [Au-(O4NCS2)]2 and tetranuclear [Au(SSCOOH)]4 complexes.

Synthesis

Ammonium dithiocarbamate

513-74-6

Levulinic acid

123-76-2

2-Mercapto-4-methyl-5-thiazoleacetic acid

34272-64-5

To the reactor were added 100 kg of acetylpropionic acid and 1000 L of carbon tetrachloride. Under stirring conditions, 176 kg of sodium bromide was added, followed by a slow dropwise addition of 260 kg of hydrogen peroxide solution. The reaction mixture was heated to 60 °C and maintained at this temperature for 2.5 hours. Upon completion of the reaction, water was added for washing to separate the organic and aqueous phases. The aqueous phase was treated as waste water. To the organic phase, 75 kg of ammonium dithiocarbamate, 1000 kg of water and 22 kg of sodium carbonate were added directly to the organic phase to carry out the cyclization reaction. After completion of the reaction, the aqueous phase was acidified with acid at pH=1.5 to precipitate the product. Finally, 132 kg of 2-mercapto-4-methyl-5-thiazoleacetic acid was obtained with 99.92% purity and 80.99% yield.

References

[1] Patent: CN107602503, 2018, A. Location in patent: Paragraph 0024; 0025; 0026; 0027; 0028; 0029-0034

513-74-6
123-76-2
34272-64-5
Synthesis of 2-Mercapto-4-methyl-5-thiazoleacetic acid from Ammonium dithiocarbamate and Levulinic acid

2-Mercapto-4-methyl-5-thiazoleacetic acid Preparation Products And Raw materials

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Moxin Chemicals
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View Lastest Price from 2-Mercapto-4-methyl-5-thiazoleacetic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cefodizime impurity 4 pictures 2025-12-16 Cefodizime impurity 4
34272-64-5
10mg 95 100000 Moxin Chemicals
2-Mercapto-4-methyl-5-thiazoleacetic acid pictures 2022-02-25 2-Mercapto-4-methyl-5-thiazoleacetic acid
34272-64-5
$199.00 1KG 99% 1 ton Hong Kong Tiansheng New Material Trading Co., Ltd
2-Mercapto-4-methyl-5-thiazoleacetic acid pictures 2022-02-25 2-Mercapto-4-methyl-5-thiazoleacetic acid
34272-64-5
$12.00 1KG 99% 20tons Hong Kong Tiansheng New Material Trading Co., Ltd

2-Mercapto-4-methyl-5-thiazoleacetic acid Spectrum

2-Mercapto-4-methylthizaol-5-yl)acetic acid MMTA 2-(2-Mercapto-4-methyl-1,3-thiazole-5-yl) acetic Acid 2-Mercapto-4-Methylthiazol 2-(4-Methyl-2-thioxo-2,3-dihydrothiazol-5-yl)acetic acid (2-Mercapto-4-Methyl-5-thiazolyl)acetic Acid Cefodizime Impurity (2-Mercapto-4-methyl-5-thiazoleacetic acid) 2-Mercapto-4-methyl- 2-(4-Methyl-2-sulfanyl-1,3-thiazol-5-yl)acetic acid 2,3-Dihydro-4-methyl-2-thioxo-5-thiazoleacetic acid 5-(Carboxymethyl)-2-mercapto-4-methylthiazole 2-mercapto-4-methyl-5-thiazoleaceticaci 2-MERCAPTO-4-METHYL-5-THIAZOLEACETIC ACID 2-MERCAPTO-4-METHYLTHIAZOLE-5-ACETIC ACID 2,3-dihydro-4-methyl-2-thioxothiazol-5-acetic acid 2-MERCAPTO-4-METHYL-5-THIAZOLE ACETIC ACID(MMTA) 2-mercapto-4-methylthiazole-5-yl acetic acid 2-Mercapto-4-Methyl-5-Thiazole 2-(2-Mercapto-4-Methyl-1,3-Thiazole-5-yl) Acetic Acid MTAA:2-MERCAPTO-4-METHYL-1,3-THIAZOL-5-YL-ACETIC ACID SIDE CHAIN OF CEFODIZIME /2-MERCAPTO-4-METHYL-5-THIAZOLEACETIC ACID (4-Methyl-2-thioxo-2,3-dihydro-thiazol-5-yl)-acetic acid (4-Methyl-2-thioxo-2,3-dihydro-thiazol-5-yl)- 4-Methyl-2-mercaptothiazole-5-acetic acid MMTA Cefodizime Impurity 1 Cefodizime Impurity A 2-mercapto-2-(4-methyl-5-thiazolyl)acetic acid Etaa (2-Mercapto-4-methyl-5-thiazolyl)aceticAcid> 5-Thiazoleacetic acid, 2,3-dihydro-4-methyl-2-thioxo- Cefodizime 3-position side chain (See C4X-12018)Cefodizime Impurity 1 MTAA/MMTA 2-Mercapto-4-methyl-1,3-thiazole-5-carboxylicAcid(Assumed) 2-(2-mercapto-4-methylthiazol-5-yl)acetic acid Cefodizime Side Chain Acid 34272-64-5 C6H7NO2S2 Building Blocks Heterocyclic Building Blocks Thiazoles Building Blocks Heterocyclic Building Blocks Thiazoles Organic acids Heterocyclic Compounds
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