FK-021
- CAS No.
- 101193-62-8
- Chemical Name:
- FK-021
- Synonyms
- FK-021;FR-71021;Quinotolast sodium;Quinotolast sodium anhydrous;4-Oxo-1-phenoxy-N-(1-sodio-1H-tetrazol-5-yl)-4H-quinolizine-3-carboxamide
- CBNumber:
- CB52145955
- Molecular Formula:
- C17H13N6NaO3
- Molecular Weight:
- 372.32
- MDL Number:
- MFCD31382142
- MOL File:
- 101193-62-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Quinotolast sodium 98.38% | CS-6569 | 5mg | $542 |
| Quinotolast sodium 98.38% | CS-6569 | 10mg | $921 |
| Quinotolast sodium 98.38% | CS-6569 | 25mg | $1787 |
| Quinotolast sodium 98.38% | CS-6569 | 50mg | $2817 |
| Quinotolast sodium 98.38% | CS-6569 | 100mg | $4333 |
| storage temp. | Store at -20°C |
|---|---|
| solubility | Soluble in DMSO |
| form | Solid |
| color | Light yellow to yellow |
| FDA UNII | G8K8E99F1S |
FK-021 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-6569 | Quinotolast sodium 98.38% | 101193-62-8 | 5mg | $542 | 2026-06-04 | Buy |
| ChemScene | CS-6569 | Quinotolast sodium 98.38% | 101193-62-8 | 10mg | $921 | 2026-06-04 | Buy |
| ChemScene | CS-6569 | Quinotolast sodium 98.38% | 101193-62-8 | 25mg | $1787 | 2026-06-04 | Buy |
| ChemScene | CS-6569 | Quinotolast sodium 98.38% | 101193-62-8 | 50mg | $2817 | 2026-06-04 | Buy |
| ChemScene | CS-6569 | Quinotolast sodium 98.38% | 101193-62-8 | 100mg | $4333 | 2026-06-04 | Buy |
FK-021 Chemical Properties,Uses,Production
Uses
Quinotolast sodium in the concentration range of 1-100 μg/mL inhibits histamine, LTC4 and PGD2 release in a concentration-dependent manner.
in vivo
Quinotolast potently inhibits such type I allergic reactions as passive cutaneous anaphylaxis (PCA) and anaphylactic bronchoconstriction in rats by both intravenous and oral dosing. When Quinotolast is given i.v. to rats, Quinotolast, dose-dependently inhibits PCA. The doses of Quinotolast required to inhibit the reaction by 50% (ED50) is 0.0063 mg/kg. Given p.o., Quinotolast inhibits the reaction. ED50 value for Quinotolast is 0.0081 mg/kg. Although almost complete inhibition is observed with Quinotolast at a dose of 0.32 mg/kg, its effect is slightly attenuated at a dose of 1 mg/kg[2].
IC 50
Histamine; LTC4
References
[1] Okayama Y, et al. Inhibition of histamine and eicosanoid release from dispersed human lung cells in vitro byquinotolast. Jpn J Pharmacol. 1995 Dec;69(4):375-80. DOI:10.1254/jjp.69.375
[2] Kobayashi K, et al. Effects of quinotolast, a new orally active antiallergic drug, on experimental allergic models. Jpn J Pharmacol. 1993 Sep;63(1):73-81. DOI:10.1254/jjp.63.73
FK-021 Preparation Products And Raw materials
Raw materials
Preparation Products
FK-021 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 19956 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; | psaitong@jm-bio.com | China | 29757 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24957 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6051 | 58 |
View Lastest Price from FK-021 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-11 | Quinotolast sodium
101193-62-8
|
$1650.00-3100.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2025-07-28 | Quinotolast sodium
101193-62-8
|
$1650.00-3100.00 | 10g | TargetMol Chemicals Inc. |
-
- Quinotolast sodium
101193-62-8
- $1650.00-3100.00
- TargetMol Chemicals Inc.
-
- Quinotolast sodium
101193-62-8
- $1650.00-3100.00
- TargetMol Chemicals Inc.
