Methyl 2-ethoxybenzimidazole-7-carboxylate
- CAS No.
- 150058-27-8
- Chemical Name:
- Methyl 2-ethoxybenzimidazole-7-carboxylate
- Synonyms
- Azilsartan Impurity 38;Methyl-2-ethoxy-1H-benz;Candesartan intermediate;Candesartan BenziMidazole Ethoxy IMpurity;Methyl 2-ethoxybenzimidazole-7-carboxylate;Methyl 2-ethoxybenzoimidazole-4-carboxylate;Candesartan Benzimidazole Ethoxy Methyl Ester;Methyl 2-ethoxy-3H-benziMidazole-4-carboxylate;methyl 2-ethoxy-1H-benzimidazole-4-carboxylate;Methyl 2-ethoxybenziMidazole-4-carboxylate, 97%
- CBNumber:
- CB52490053
- Molecular Formula:
- C11H12N2O3
- Molecular Weight:
- 220.22
- MDL Number:
- MFCD14636510
- MOL File:
- 150058-27-8.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester | TRC-E890465-25G | 25g | $1286 |
| 2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester | TRC-E890465-2.5G | 2.5g | $167 |
| 2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester | 011432 | 2.5g | $418 |
| Candesartan impurity 26 ≥98% | CS-0042042 | 1g | $9 |
| Candesartan impurity 26 ≥98% | CS-0042042 | 5g | $11 |
| More product size | |||
| Boiling point | 373.1±34.0 °C(Predicted) |
|---|---|
| Density | 1.269 |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform, Methanol |
| form | Solid |
| pka | 8.99±0.30(Predicted) |
| color | Dark Reddish Orange to Dark Brown |
| InChI | InChI=1S/C11H12N2O3/c1-3-16-11-12-8-6-4-5-7(9(8)13-11)10(14)15-2/h4-6H,3H2,1-2H3,(H,12,13) |
| InChIKey | MOPLKVMMSFGZIR-UHFFFAOYSA-N |
| SMILES | C1(OCC)NC2=C(C(OC)=O)C=CC=C2N=1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 |
Methyl 2-ethoxybenzimidazole-7-carboxylate price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-E890465-25G | 2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester | 150058-27-8 | 25g | $1286 | 2026-06-03 | Buy |
| TRC | TRC-E890465-2.5G | 2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester | 150058-27-8 | 2.5g | $167 | 2026-06-03 | Buy |
| Usbiological | 011432 | 2-Ethoxy-3H-benzimidazole-4-carboxylic Acid Methyl Ester | 150058-27-8 | 2.5g | $418 | 2026-06-03 | Buy |
| ChemScene | CS-0042042 | Candesartan impurity 26 ≥98% | 150058-27-8 | 1g | $9 | 2026-06-04 | Buy |
| ChemScene | CS-0042042 | Candesartan impurity 26 ≥98% | 150058-27-8 | 5g | $11 | 2026-06-04 | Buy |
Methyl 2-ethoxybenzimidazole-7-carboxylate Chemical Properties,Uses,Production
Chemical Properties
Dark Reddish Orange Solid
Uses
An intermediate in the preparation of labelled Candesartan.
Synthesis
78-09-1
107582-20-7
150058-27-8
1. Methyl 2-amino-3-nitrobenzoate (150.0 g, 0.765 mol) was placed in an autoclave and ethyl acetate (1000 mL) and nickel ruanne (75 g) were added. The reaction mixture was stirred at 12-15 °C for 20-25 h under hydrogen pressure (2-3 kg/cm2). Upon completion of the reaction, the catalyst was removed by diatomaceous earth filtration and the diatomaceous earth was washed with ethyl acetate (150 mL). The filtrate was distilled under reduced pressure and the solvent was completely removed at 45-50 °C. 2. Acetic acid (171 mL) was added to the residue, and raw tetraethyl carbonate (180 g) was added slowly over 30-45 minutes. The reaction mixture was stirred at 25-35 °C for 2-3 hours. 3. Cool the reaction mixture to 0-5 °C and slowly add water (750 mL) over 15-30 min. The precipitated solid was filtered and washed sequentially with water (150 mL) and ethyl acetate (150 mL). 4. The resulting solid was dried at 55-65 °C for 10-12 h to afford methyl 2-ethoxy-1H-benzo[d]imidazole-7-carboxylate (140 g, 83.1% yield).
References
[1] Patent: WO2006/15134, 2006, A1. Location in patent: Page/Page column 15; 16
[2] Patent: CN104876877, 2018, B. Location in patent: Paragraph 0033; 0069-0072
Methyl 2-ethoxybenzimidazole-7-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Anhui Ruihan Technology Co., Ltd | +undefined17756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8618017249410 | jack.li@time-chemicals.com | China | 1803 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29812 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10403 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 904 | 58 |
| Shanghai Worldyang Chemical Co.,Ltd. | +86-021-56795779 +86-13651600618 | sales@worldyachem.com | China | 967 | 58 |
View Lastest Price from Methyl 2-ethoxybenzimidazole-7-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-01 | Methyl 2-ethoxybenzimidazole-7-carboxylate
150058-27-8
|
$260.00-300.00 | 100kg | 99.99% | 100Tons | Hebei Dangtong Import and export Co LTD | |
 |
2024-03-28 | Methyl-2-ethoxybenzimidazole-7-carboxylate
150058-27-8
|
25KG | 98%-99% | PNP Biotech Co. Ltd | |||
 |
2023-09-07 | Methyl 2-ethoxybenzimidazole-7-carboxylate
150058-27-8
|
$30.00 | 1kg | 99% | 20 tons | Anhui Ruihan Technology Co., Ltd |
-
- Methyl 2-ethoxybenzimidazole-7-carboxylate
150058-27-8
- $260.00-300.00
- 99.99%
- Hebei Dangtong Import and export Co LTD
-
- Methyl-2-ethoxybenzimidazole-7-carboxylate
150058-27-8
- $0.00
- 98%-99%
- PNP Biotech Co. Ltd
-
- Methyl 2-ethoxybenzimidazole-7-carboxylate
150058-27-8
- $30.00
- 99%
- Anhui Ruihan Technology Co., Ltd
150058-27-8(Methyl 2-ethoxybenzimidazole-7-carboxylate)Related Search:
1of2
