ChemicalBook >> CAS DataBase List >>3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
![3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Structure](CAS/GIF/1022150-12-4.gif)
- CAS No.
- 1022150-12-4
- Chemical Name:
- 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
- Synonyms
- (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine;ibrutinib N-1;3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride;IBT6A ，E2250;Ilutinib impurity 18;IBT6A, 10 mM in DMSO;Ibrutinib Impurity 18;4-d]pyriMidin-4-ylaMine;Ibrutinib intermediate 1
- CBNumber:
- CB52623905
- Molecular Formula:
- C22H22N6O
- Molecular Weight:
- 386.45
- MDL Number:
- MFCD20482137
- MOL File:
- 1022150-12-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-27 17:00:41
| Product description | Number | Pack Size | Price |
| (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 463775 | 500mg | $382 |
| (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 463775 | 1g | $531 |
| (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | TRC-P318770-500MG | 500mg | $167 |
| (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | TRC-P318770-1G | 1g | $260 |
| IBT6A ≥98% | CS-2435 | 100mg | $16 |
| More product size | |||
| Melting point | 133-136oC |
|---|---|
| Boiling point | 626.3±55.0 °C(Predicted) |
| Density | 1.39±0.1 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 9.00±0.10(Predicted) |
| form | Solid |
| color | White to Pale Yellow |
| optical activity | -9.6828°(C=0.5249g/100ml MEOH) |
| InChIKey | GPSQYTDPBDNDGI-MRXNPFEDSA-N |
| SMILES | C1=NC(N)=C2C(C3=CC=C(OC4=CC=CC=C4)C=C3)=NN([C@@H]3CCCNC3)C2=N1 |
| FDA UNII | NR6GN4MC2R |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319 |
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| REACH Registrations | Active |
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 463775 | (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1022150-12-4 | 500mg | $382 | 2026-06-03 | Buy |
| Usbiological | 463775 | (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1022150-12-4 | 1g | $531 | 2026-06-03 | Buy |
| TRC | TRC-P318770-500MG | (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1022150-12-4 | 500mg | $167 | 2026-06-03 | Buy |
| TRC | TRC-P318770-1G | (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | 1022150-12-4 | 1g | $260 | 2026-06-03 | Buy |
| ChemScene | CS-2435 | IBT6A ≥98% | 1022150-12-4 | 100mg | $16 | 2026-06-04 | Buy |
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Chemical Properties,Uses,Production
Description
IBT6A is a Btk kinase inhibitor. This compound is a precurser for the manufacture of ibrutinib.
Uses
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton''s tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.
Synthesis of 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine from 3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine and (S)-1-Boc-3-hydroxypiperidine
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 295)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20120 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
| Lianyungang happen teng technology co., LTD | 15950718863 | wang666xt@163.com | CHINA | 295 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 965 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
View Lastest Price from 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | IBT6A
1022150-12-4
|
$42.00 | 99.88% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | IBT6A
1022150-12-4
|
$42.00 | 99.88% | 10g | TargetMol Chemicals Inc. | ||
![3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine pictures](/ProductImageEN/2024-04/Small/afd73bf1-3c39-4ab3-a22d-cf40b5ff660b.gif) |
2026-07-09 | 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
1022150-12-4
|
$3.00-10.00 | 1kg | 99% | Henan Fengda Chemical Co., Ltd |
-
- IBT6A
1022150-12-4
- $42.00
- 99.88%
- TargetMol Chemicals Inc.
-
- IBT6A
1022150-12-4
- $42.00
- 99.88%
- TargetMol Chemicals Inc.
-
- 3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
1022150-12-4
- $3.00-10.00
- 99%
- Henan Fengda Chemical Co., Ltd
1022150-12-4(3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine)Related Search:
3-(4-Phenoxyphenyl)-1-(4-piperidinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Btk inhibitor 1 (R enantioMer hydrochloride)
Ibrutinib Impurity 21
Ibrutinib Impurity 10
Imatinib Impurity 72
(S)-Ibrutinib
Chidamide
(R)-1-[3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]ethanone
Esmolol Impurity 2 HCl
Cilastatin
1of4
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
3-(4-Phenoxy-phenyl)-1-(R)-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
Btk inhibitor 1 (R enantioMer)
Ibrutinib intermeidate N-1
3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyriMidin-4-aMine
3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-1H-Pyrazolo[3,4-d]pyrimidin-4-amine
Ibrutinib (PCI-32765) Intermediates
2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[3-methyl-3-(4-methyl-1-piperazinyl)
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine(Btk inhibitor 1 R enantiomer)
(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
(R)-4-Amino-3-(4-phenoxyphenyl)-1-(3-piperidyl)-1H-pyrazolo[3,4-d]pyrimidine
Ibrutinib Impurity 18
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)
(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1H-pyrazolo[3,4-d]pyrimidine-4-amine
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine 1022150-12-4
(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1022150-12-4
3-(4-phenoxyphenyl)-1-[(3R)-piperidin-3-yl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine
(R)-3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
Ibrutinib N-1 (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
(S)-Ibrutinib N-Desacryloyl Impurity
(R)-3-(4-phenoxyphenyl)-1-(piperidine-3-yl)-1 H- pyrazole [3,4- d] pyrimidine-4-amine
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-
Ibrutinib N-Desacryloyl Impurity
3- (4-phenoxy-phenyl) -1-piperidine-3-yl-1H-pyrazolium [3, 4-D] pyrimidin-4-ylamine
Ibrutinib intermediate 1
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3
4-d]pyriMidin-4-ylaMine
(R)-3-(4-Phenoxyphenyl)-1
-（piperidin-3-yl）pyrazolo [3,4-D]pyrimidin-4-ylamine
3-(4-phenoxyphenyl)-1-(3-piperidyl)pyrazolo[3,4-d]pyrimidin-...
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMi
TIANFUCHEM--1022150-12-4---3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-ylaMine
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride
3-(4-phenoxypheny)1-((3R)-3-pipeidinyl)-1H-pyrazolo[3.4-dleyrimidin-4-amine
(R) -3- (4-phenoxyphenyl) -1- (piperidin-3-yl) pyrazolo [3,4-D] pyrimidin-4-amine
Ilutinib impurity 18
Irupuni N-1 intermediate
IBT6A, 10 mM in DMSO
Intermediate of Ibrutinib
(R)-3-(4-PhenChemicalbookoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
IBT6A ，E2250
3-(4-Phenoxy-phenyl)-1-piperidin-3-yl-1H-pyrazolo[3,4-d]pyriMidin-4-
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (Intermediate of Ibrutinib)
3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
(R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine
ibrutinib N-1
1022150-12-4
022150-12-4
Ibrutinib
Intermediates
