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ChemicalBook >> CAS DataBase List >>3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester

CAS No.
1220418-77-8
Chemical Name:
3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester
Synonyms
Methyl 6-broMoquinoline-3-carboxylate;Methyl 6-bromo-3-quinolinecarboxylate;6-bromoquinoline-3-carboxylic acid methyl ester;Methyl6-bromoquinoline-3-carboxylate,95%,QY-1716;3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester
CBNumber:
CB52642308
Molecular Formula:
C11H8BrNO2
Molecular Weight:
266.09
MDL Number:
MFCD20922336
MOL File:
1220418-77-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:02
Product description Number Pack Size Price
Methyl 6-bromoquinoline-3-carboxylate VYB41877 100mg $326
Methyl 6-bromoquinoline-3-carboxylate VYB41877 1g $837.8
Methyl 6-bromoquinoline-3-carboxylate 98% AA0016LM 100mg $140
Methyl 6-bromoquinoline-3-carboxylate 98% AA0016LM 250mg $207
Methyl 6-bromoquinoline-3-carboxylate 98% AA0016LM 1g $507

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester Properties

Boiling point 348.5±22.0 °C(Predicted)
Density 1.557±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 2.30±0.14(Predicted)

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth VYB41877 Methyl 6-bromoquinoline-3-carboxylate 1220418-77-8 100mg $326 2026-06-05 Buy
Biosynth VYB41877 Methyl 6-bromoquinoline-3-carboxylate 1220418-77-8 1g $837.8 2026-06-05 Buy
aablocks AA0016LM Methyl 6-bromoquinoline-3-carboxylate 98% 1220418-77-8 100mg $140 2026-05-28 Buy
aablocks AA0016LM Methyl 6-bromoquinoline-3-carboxylate 98% 1220418-77-8 250mg $207 2026-05-28 Buy
aablocks AA0016LM Methyl 6-bromoquinoline-3-carboxylate 98% 1220418-77-8 1g $507 2026-05-28 Buy
Product number Packaging Price Buy
VYB41877 100mg $326 Buy
VYB41877 1g $837.8 Buy
AA0016LM 100mg $140 Buy
AA0016LM 250mg $207 Buy
AA0016LM 1g $507 Buy

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

6-BROMOQUINOLINE-3-CARBOXYLIC ACID

798545-30-9

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester

1220418-77-8

Example 1: Synthesis of tert-butyl {3-[(hydroxyamino)carbonyl]quinolin-6-yl}carbamate (Compound 1-21, Int-2) Step 1: Synthesis of methyl 6-bromoquinoline-3-carboxylate (Intermediate 1) [00161] To a solution of 6-bromoquinoline-3-carboxylic acid (3 g, 11.9 mmol) in methanol (55 mL) was slowly added concentrated sulfuric acid (0.32 mL, 6 mmol). The reaction mixture was stirred and refluxed at 85 °C for 96 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted to 7 by slow addition of saturated sodium bicarbonate solution.During neutralization, methyl 6-bromoquinoline-3-carboxylate precipitated as a solid, which was collected by filtration (Intermediate 1, 2.77 g, 97% yield). Product Characterization: LC-MS (FA) ES+ m/z: 266 [M+H]+. 1H NMR (400 MHz, DMSO-d6) δ ppm: 9.33 (d, J = 2.1 Hz, 1H), 9.01 (d, J = 2.1 Hz, 1H), 8.53 (t, J = 1.3 Hz, 1H), 8.07-8.01 (m, 2H), 3.95 (s, 3H).

References

[1] Patent: WO2011/146591, 2011, A1. Location in patent: Page/Page column 60
[2] Patent: WO2014/86697, 2014, A1. Location in patent: Page/Page column 46-47

67-56-1
798545-30-9
1220418-77-8
Synthesis of 3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester from Methanol and 6-BROMOQUINOLINE-3-CARBOXYLIC ACID

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester Preparation Products And Raw materials

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1220418-77-8(3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester)Related Search:

3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester 6-bromoquinoline-3-carboxylic acid methyl ester Methyl 6-bromo-3-quinolinecarboxylate Methyl6-bromoquinoline-3-carboxylate,95%,QY-1716 Methyl 6-broMoquinoline-3-carboxylate 1220418-77-8
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