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ChemicalBook >> CAS DataBase List >>N-(3-hydroxyphenyl)acrylamide

N-(3-hydroxyphenyl)acrylamide

CAS No.
13040-21-6
Chemical Name:
N-(3-hydroxyphenyl)acrylamide
Synonyms
172593;N-tosyl-3-aminophenol;N-(3-hydroxyphenyl)acrylamide;2-Propenamide, N-(3-hydroxyphenyl)-
CBNumber:
CB52745227
Molecular Formula:
C9H9NO2
Molecular Weight:
163.17
MDL Number:
MFCD00599810
MOL File:
13040-21-6.mol
Last updated:2026-05-28 05:31:05
Product description Number Pack Size Price
N-(3-Hydroxyphenyl)acrylamide 97% AS117672 1g $31
N-(3-Hydroxyphenyl)acrylamide 97% AS117672 5g $62
N-(3-Hydroxyphenyl)acrylamide 97% AS117672 25g $142
N-(3-Hydroxyphenyl)acrylamide 97% H51779 250mg $102
N-(3-Hydroxyphenyl)acrylamide 97% H51779 1g $121

N-(3-hydroxyphenyl)acrylamide Properties

Boiling point 382.9±34.0 °C(Predicted)
Density 1.231±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 9.51±0.10(Predicted)
Appearance off-white solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H319
Precautionary statements  P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

N-(3-hydroxyphenyl)acrylamide price More Price(28)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS117672 N-(3-Hydroxyphenyl)acrylamide 97% 13040-21-6 1g $31 2026-06-04 Buy
Activate Scientific AS117672 N-(3-Hydroxyphenyl)acrylamide 97% 13040-21-6 5g $62 2026-06-04 Buy
Activate Scientific AS117672 N-(3-Hydroxyphenyl)acrylamide 97% 13040-21-6 25g $142 2026-06-04 Buy
Synthonix H51779 N-(3-Hydroxyphenyl)acrylamide 97% 13040-21-6 250mg $102 2026-05-06 Buy
Synthonix H51779 N-(3-Hydroxyphenyl)acrylamide 97% 13040-21-6 1g $121 2026-05-06 Buy
Product number Packaging Price Buy
AS117672 1g $31 Buy
AS117672 5g $62 Buy
AS117672 25g $142 Buy
H51779 250mg $102 Buy
H51779 1g $121 Buy

N-(3-hydroxyphenyl)acrylamide Chemical Properties,Uses,Production

Synthesis

Acryloyl chloride

814-68-6

3-Aminophenol

591-27-5

N-(3-hydroxyphenyl)acrylamide

13040-21-6

The general procedure for the synthesis of 3-acrylamido-phenol from acryloyl chloride and 3-aminophenol is as follows: sodium bicarbonate (5.6 g, 0.067 mol) was added to a mixture of tetrahydrofuran (100 mL) and water (30 mL) of 3-aminophenol (5.0 g, 0.045 mol), followed by a slow dropwise addition of acryloyl chloride (3.6 mL, 0.045 mol) . The reaction mixture was stirred at room temperature for 3.5 hours. After completion of the reaction, dichloromethane was added for extraction and the organic layer was washed with aqueous ammonium chloride. After separation of the organic layer, it was dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The resulting crude product was recrystallized by a solvent mixture of dichloromethane and ether to give 3-acrylamido-phenol (2.9 g, 40% yield). The product was characterized by 1H-NMR (300 MHz, DMSO-d6): δ 5.73 (dd, 1H), 6.24 (dd, 1H), 6.42 (m, 2H), 7.04 (m, 2H), 7.24 (s, 1H), 9.39 (s, 1H), 9.97 (s, 1H).

References

[1] Patent: WO2013/100631, 2013, A1. Location in patent: Page/Page column 13; 15-16
[2] Patent: EP2058318, 2009, A1
[3] European Journal of Medicinal Chemistry, 2017, vol. 133, p. 329 - 339
[4] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 10, p. 2724 - 2729
[5] European Journal of Medicinal Chemistry, 2017, vol. 135, p. 60 - 69

N-(3-hydroxyphenyl)acrylamide Preparation Products And Raw materials

N-(3-hydroxyphenyl)acrylamide Suppliers

Global( 57)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co
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Labnetwork lnc.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Wuhan Topule Biopharmaceutical Co., Ltd
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Henan Fengda Chemical Co., Ltd
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Aladdin Scientific
tp@aladdinsci.com United States 52906 58
Suzhou ARTK Medchem Co., Ltd.
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Shandong Liteng Biotechnology Co. , Ltd.
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SHANGHAI KEAN TECHNOLOGY CO., LTD.
+8613817748580 cooperation@kean-chem.com China 40048 58

View Lastest Price from N-(3-hydroxyphenyl)acrylamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-(3-hydroxyphenyl)acrylamide pictures 2020-01-13 N-(3-hydroxyphenyl)acrylamide
13040-21-6
$6.68 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

N-(3-hydroxyphenyl)acrylamide Spectrum

N-(3-hydroxyphenyl)acrylamide 2-Propenamide, N-(3-hydroxyphenyl)- 172593 N-tosyl-3-aminophenol 13040-21-6
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