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ChemicalBook >> CAS DataBase List >>5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE

CAS No.
6325-94-6
Chemical Name:
5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE
Synonyms
NSC 31153;Aspergillus niger-IN-1;5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE;(Z)-5-(2-hydroxybenzylidene)thiazolidine-2,4-dione;5-(2-Hydroxybenzylidene)-1,3-thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[(2-hydroxyphenyl)methylene]-;5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione
CBNumber:
CB52751989
Molecular Formula:
C10H7NO3S
Molecular Weight:
221.23
MDL Number:
MFCD00186341
MOL File:
6325-94-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-28 20:32:40
Product description Number Pack Size Price
5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE AldrichCPR S21548 1 unit $32.7
5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE Aldrich S21548 50mg $29.8
NSC 31153 ≥98% AA01DU7P 5mg $44
NSC 31153 95+% AA01DU7P 50mg $95
NSC 31153 95+% AA01DU7P 100mg $160
More product size

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE Properties

Melting point 134-136 °C(Solvent: Methanol)
Density 1.542±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka 6.280±0.10(predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S21548 5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE AldrichCPR 6325-94-6 1 unit $32.7 2026-04-30 Buy
Sigma-Aldrich S21548 5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE Aldrich 6325-94-6 50mg $29.8 2024-03-01 Buy
aablocks AA01DU7P NSC 31153 ≥98% 6325-94-6 5mg $44 2026-05-29 Buy
aablocks AA01DU7P NSC 31153 95+% 6325-94-6 50mg $95 2026-05-29 Buy
aablocks AA01DU7P NSC 31153 95+% 6325-94-6 100mg $160 2026-05-29 Buy
Product number Packaging Price Buy
S21548 1 unit $32.7 Buy
S21548 50mg $29.8 Buy
AA01DU7P 5mg $44 Buy
AA01DU7P 50mg $95 Buy
AA01DU7P 100mg $160 Buy

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE Chemical Properties,Uses,Production

Uses

Aspergillus niger-IN-1 (Compound 17), a derivative of thiazolidine-2,4-dione, acts as an antimicrobial agent. Aspergillus niger-IN-1 exhibited antimicrobial activity against various bacterial and fungal strains, including Bacillus subtilis, Staphylococcus aureus, Klebsiella pneumonia, Escherichia coli, Salmonella typhi, Candida albicans and Aspergillus niger, with MIC values of 11.3, 5.65, 11.3, 5.65, 5.65, 5.65, and 5.65 μM/mL, respectively [1].

References

[1] Sucheta, et al. Synthesis, SAR and in vitro therapeutic potentials of thiazolidine-2,4-diones. Chem Cent J. 2018 Dec 4;12(1):129. DOI:10.1186/s13065-018-0496-0

2295-31-0
90-02-8
6325-94-6
Synthesis of 5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE from 2,4-Thiazolidinedione and Salicylaldehyde

5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 21)Suppliers
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ATK CHEMICAL COMPANY LIMITED
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TargetMol Chemicals Inc.
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ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8000 62
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 29660 68
5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE NSC 31153 5-(2-Hydroxybenzylidene)-1,3-thiazolidine-2,4-dione 2,4-Thiazolidinedione, 5-[(2-hydroxyphenyl)methylene]- 5-[(2-Hydroxyphenyl)methylidene]-1,3-thiazolidine-2,4-dione (Z)-5-(2-hydroxybenzylidene)thiazolidine-2,4-dione Aspergillus niger-IN-1 6325-94-6
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