zaragozic acid C
- CAS No.
- 146389-62-0
- Chemical Name:
- zaragozic acid C
- Synonyms
- 350;L697350;L-697350;L 697350;L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-12-(phenylmethyl)-, 11-acetate 5-[(4E,6R)-6-methyl-9-phenyl-4-nonenoate], (7S)-
- CBNumber:
- CB53352273
- Molecular Formula:
- C40H50O14
- Molecular Weight:
- 754.8166
- MDL Number:
- MOL File:
- 146389-62-0.mol
| alpha | D20 +9.6° (c = 0.29 in ethanol) |
|---|---|
| Boiling point | 898.3±65.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| pka | 1.49±0.70(Predicted) |
| FDA UNII | 04ISX24T1B |
zaragozic acid C Chemical Properties,Uses,Production
Uses
Zaragozic acid C (L-697350) is a potent sterol synthase inhibitor with potential antitumor activity. Zaragozic acid C contains multiple hydroxyl and alkyl substituents in its chemical structure, demonstrating complex functionalization capabilities. The synthesis of zaragozic acid C involves a photochemical C(sp3)-H acylation reaction, which resolves the challenging carbon substitution problem in the synthesis[1].
Definition
ChEBI: Zaragozic acid C is a polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. It has a role as an EC 2.5.1.21 (squalene synthase) inhibitor and a fungal metabolite. It is an acetate ester, a cyclic ketal, an oxabicycloalkane, a polyketide, a tertiary alcohol and a tricarboxylic acid.
References
[1] Total Synthesis of Zaragozic Acid C: Implementation of Photochemical C(sp3)-H Acylation DOI:10.1021/jacs.6b13263
zaragozic acid C Preparation Products And Raw materials
Raw materials
Preparation Products
zaragozic acid C Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29869 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
