METHYSTICIN
- CAS No.
- 20697-20-5
- Chemical Name:
- METHYSTICIN
- Synonyms
- KAVATIN;KAVAHIN;metysticin;METHYSTICIN;(±)-Methysticin;(±)-Methystici);METHYSTICIN USP/EP/BP;Methysticin (DL-Methysticin;5,6-Dihydro-4-methoxy-6-(3,4-(methylenedioxy)styryl)-2H-pyran-2-one;6-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
- CBNumber:
- CB5456785
- Molecular Formula:
- C15H14O5
- Molecular Weight:
- 274.27
- MDL Number:
- MFCD00221732
- MOL File:
- 20697-20-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| DL-Methysticin | VAA69720 | 5mg | $900 |
| DL-Methysticin | VAA69720 | 2mg | $900 |
| DL-Methysticin | VAA69720 | 1mg | $900 |
| DL-Methysticin | VAA69720 | 10mg | $900 |
| DL-Methysticin | VAA69720 | 0.5mg | $900 |
| More product size | |||
| Melting point | 129-131 °C |
|---|---|
| Boiling point | 496.5±45.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| FDA UNII | M832AIJ6HX |
METHYSTICIN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | VAA69720 | DL-Methysticin | 20697-20-5 | 5mg | $900 | 2026-06-05 | Buy |
| Biosynth | VAA69720 | DL-Methysticin | 20697-20-5 | 2mg | $900 | 2026-06-05 | Buy |
| Biosynth | VAA69720 | DL-Methysticin | 20697-20-5 | 1mg | $900 | 2026-06-05 | Buy |
| Biosynth | VAA69720 | DL-Methysticin | 20697-20-5 | 10mg | $900 | 2026-06-05 | Buy |
| Biosynth | VAA69720 | DL-Methysticin | 20697-20-5 | 0.5mg | $900 | 2026-06-05 | Buy |
METHYSTICIN Chemical Properties,Uses,Production
Uses
DL-Methysticin is a useful synthetic compound.
in vivo
The kavalactone Methysticin (6 mg/kg) is administered once a week for a period of 6 months to 6 month old transgenic APP/Psen1 mice by oral gavage. Methysticin treatment activates the Nrf2 pathway in the hippocampus and cortex of mice. The Aβ deposition in brains of Methysticin-treated APP/Psen1 mice is not altered compared to untreated mice. However, Methysticin treatment significantly reduces microgliosis, astrogliosis and secretion of the pro-inflammatory cytokines TNF-α and IL-17A. Methysticin treatment results in a significant activation of the Nrf2/ARE pathway in hippocampus and the cortex but not in the midbrain and cerebellum of ARE-luciferase reporter gene mice. Methysticin treatment significantly increases the expression of both genes compared to untreated animals[2].
IC 50
CYP1A1
METHYSTICIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3618 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +86-15195660023 | 3899766280@qq.com | China | 26349 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43392 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Hangzhou Yuhao Chemical Technology Co., Ltd | -- | info@yuhaochemical.com | China | 6372 | 52 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
