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ChemicalBook >> CAS DataBase List >>4-FLUORO-1-NAPHTHALDEHYDE

4-FLUORO-1-NAPHTHALDEHYDE

CAS No.
172033-73-7
Chemical Name:
4-FLUORO-1-NAPHTHALDEHYDE
Synonyms
4-Fluoro-1-phthaldehyde;4-FLUORO-1-NAPHTHALDEHYDE;4-Fluoro-1-naphthaldehyde 97%;4-Fluoro-1-naphthaldehyde 95+%;4-fluoro-naphthalen-1-carbaldehyde;4-FLUORO-NAPHTHALENE-1-CARBALDEHYDE;4-FLUORO-1-NAPHTHALENECARBOXALDEHYDE;4-Fluoronaphthalene-1-carboxaldehyde;1-Naphthalenecarboxaldehyde, 4-fluoro-
CBNumber:
CB5476387
Molecular Formula:
C11H7FO
Molecular Weight:
174.17
MDL Number:
MFCD02261765
MOL File:
172033-73-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:21:26
Product description Number Pack Size Price
4-Fluoro-1-naphthaldehyde 97% 694886 1g $282
4-Fluoro-1-naphthaldehyde TRC-F595275-500MG 500mg $117
4-Fluoro-1-naphthaldehyde TRC-F595275-2G 2g $256
4-Fluoro-1-naphthaldehyde TRC-F595275-1G 1g $142
4-Fluoro-1-naphthaldehyde 98% PC409500 100mg $21

4-FLUORO-1-NAPHTHALDEHYDE Properties

Melting point 79-81 °C
Boiling point 307.9±15.0 °C(Predicted)
Density 1.249±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White to Pale Beige
InChI 1S/C11H7FO/c12-11-6-5-8(7-13)9-3-1-2-4-10(9)11/h1-7H
InChIKey LZUCGZVKZDBILP-UHFFFAOYSA-N
SMILES Fc1ccc(C=O)c2ccccc12
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H412
Precautionary statements  P273-P501
PPE Eyeshields, Gloves
Risk Statements  52/53
Safety Statements  61
WGK Germany  3
HazardClass  IRRITANT
HS Code  2933998090
Storage Class 11 - Combustible Solids
Hazard Classifications Aquatic Chronic 3

4-FLUORO-1-NAPHTHALDEHYDE price More Price(70)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 694886 4-Fluoro-1-naphthaldehyde 97% 172033-73-7 1g $282 2023-06-20 Buy
TRC TRC-F595275-500MG 4-Fluoro-1-naphthaldehyde 172033-73-7 500mg $117 2026-06-03 Buy
TRC TRC-F595275-2G 4-Fluoro-1-naphthaldehyde 172033-73-7 2g $256 2026-06-03 Buy
TRC TRC-F595275-1G 4-Fluoro-1-naphthaldehyde 172033-73-7 1g $142 2026-06-03 Buy
Apolloscientific PC409500 4-Fluoro-1-naphthaldehyde 98% 172033-73-7 100mg $21 2026-06-04 Buy
Product number Packaging Price Buy
694886 1g $282 Buy
TRC-F595275-500MG 500mg $117 Buy
TRC-F595275-2G 2g $256 Buy
TRC-F595275-1G 1g $142 Buy
PC409500 100mg $21 Buy

4-FLUORO-1-NAPHTHALDEHYDE Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

4-Fluoro-1-naphthaldehyde (cas# 172033-73-7) is a compound useful in organic synthesis.

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 6592, 1995 DOI: 10.1021/jo00125a055

Synthesis

1,1-Dichlorodimethyl ether

4885-02-3

1-Fluoronaphthalene

321-38-0

4-FLUORO-1-NAPHTHALDEHYDE

172033-73-7

The general procedure for the synthesis of 4-fluoro-1-naphthalenecarboxaldehyde from 1,1-dichlorodimethyl ether and 1-fluoronaphthalene was as follows: a solution of 1,1-dichlorodimethyl ether (5.9 mL, 65 mmol) in methylene chloride (30 mL) was cooled in an ice bath, followed by the addition of stannum tetrachloride (7.6 mL, 65 mmol) drop-wise over a period of 15 min. After stirring for 45 minutes, a dichloromethane (30 mL) solution of 1-fluoronaphthalene (5.5 mL, 50 mmol) was added. The reaction mixture was allowed to warm slowly to room temperature and stirred overnight. The reaction mixture was poured into ice water (100 mL) and diluted with dichloromethane (50 mL). The organic layer was separated and further diluted with dichloromethane (100 mL) followed by washing with water (3 x 50 mL). The organic layer was dried over anhydrous sodium sulfate, filtered and the solvent was removed in vacuum to give 4-fluoro-1-naphthaldehyde (7.62 g, 87% yield) as a pale yellow solid. Mass spectrum (ESI) m/z 175 (M + H)+.

References

[1] Journal of Organic Chemistry, 1995, vol. 60, # 20, p. 6592 - 6594
[2] Patent: WO2004/52890, 2004, A1. Location in patent: Page 78
[3] Patent: CN105566284, 2016, A. Location in patent: Paragraph 0267; 0268
[4] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 13, p. 3481 - 3486
[5] Patent: WO2008/407, 2008, A1. Location in patent: Page/Page column 57

4-FLUORO-1-NAPHTHALDEHYDE Preparation Products And Raw materials

4-FLUORO-1-NAPHTHALDEHYDE Suppliers

Global( 104)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Finetech Industry Limited
+86-27-8746-5837 +8619945049750 info@finetechnology-ind.com China 9539 58
Hefei Hirisun Pharmatech Co., Ltd
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Labnetwork lnc.
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Hefei TNJ Chemical Industry Co.,Ltd.
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HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 24597 58
Henan Aochuang Chemical Co.,Ltd.
+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9333 58

View Lastest Price from 4-FLUORO-1-NAPHTHALDEHYDE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-FLUORO-1-NAPHTHALDEHYDE pictures 2025-04-04 4-FLUORO-1-NAPHTHALDEHYDE
172033-73-7
1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
4-FLUORO-1-NAPHTHALDEHYDE pictures 2020-01-03 4-FLUORO-1-NAPHTHALDEHYDE
172033-73-7
$1.00 1KG 95-99% 1ton Career Henan Chemical Co

4-FLUORO-1-NAPHTHALDEHYDE Spectrum

4-Fluoronaphthalene-1-carboxaldehyde 4-FLUORO-NAPHTHALENE-1-CARBALDEHYDE 4-FLUORO-1-NAPHTHALDEHYDE 4-FLUORO-1-NAPHTHALENECARBOXALDEHYDE 4-Fluoro-1-phthaldehyde 4-Fluoro-1-naphthaldehyde 97% 4-fluoro-naphthalen-1-carbaldehyde 4-Fluoro-1-naphthaldehyde 95+% 1-Naphthalenecarboxaldehyde, 4-fluoro- 172033-73-7 Aromatics
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