Fluoxapiprolin
- CAS No.
- 1360819-11-9
- Chemical Name:
- Fluoxapiprolin
- Synonyms
- Fluoxapiprolin;2-{3-[2-(1-{2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazol-4-yl]-4,5-dihydro-1,2-oxazol-5-yl}-3-chlorophenyl methanesulfonate;Ethanone, 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]-1-[4-[4-[5-[2-chloro-6-[(methylsulfonyl)oxy]phenyl]-4,5-dihydro-3-isoxazolyl]-2-thiazolyl]-1-piperidinyl]-
- CBNumber:
- CB54768956
- Molecular Formula:
- C25H24ClF4N5O5S2
- Molecular Weight:
- 650.07
- MDL Number:
- MOL File:
- 1360819-11-9.mol
| Product description | Number | Pack Size | Price |
| FLUOXAPIPROLIN | AA02F7CQ | 10mg | $732 |
| FDA UNII | 32V6FSV7XC |
|---|
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H412-H302-H335 |
| Precautionary statements | P273-P501-P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P |
Fluoxapiprolin Chemical Properties,Uses,Production
Definition
ChEBI: 2-[(ethanesulfonyl)amino]-5-fluoro-4-[4-methyl-5-oxo-3-(trifluoromethyl)-4,5-dihydro-1H-1,2,4-triazol-1-yl]benzene-1-carbothioamide is a member of the class of 1,3-thiazoles that is 4-(1,3-thiazol-2-yl)piperidine in which the piperidine amino group is substituted by a [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl group and position 4 of the thiazole ring is substituted by a 5-{2-chloro-6-[(methylsulfonyl)oxy]phenyl}-4,5-dihydro-1,2-oxazol-3-yl group. It is an organofluorine compound, a member of 1,3-thiazoles, a N-acylpiperidine, an isoxazoline, a member of pyrazoles, a tertiary carboxamide, a member of monochlorobenzenes and a methanesulfonate ester.
Production Methods
Fluoxapiprolin is produced through a multi-step industrial synthesis typical of modern piperidinyl-amide fungicides, combining tightly controlled heterocycle construction with late stage functionalisation to achieve the molecule’s distinctive diaryl-substituted piperidine core. Commercial routes begin with preparation of the substituted piperidine scaffold, usually via catalytic hydrogenation or reductive amination of a protected precursor, followed by introduction of the difluoro- and chloro-substituted aromatic rings through sequential coupling reactions under anhydrous, high-purity conditions. The amide linkage is then formed by reacting the activated carboxylic acid derivative with the piperidinyl intermediate, often using carbodiimide or mixed-anhydride chemistry optimised for scale.
Mechanism of action
Oxysterol-binding protein homologue inhibition (OSBPI).
Pesticide Type
Fungicide
Fluoxapiprolin Preparation Products And Raw materials
Raw materials
Preparation Products
Fluoxapiprolin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chunchuang (Wuhan) Technology Co., Ltd | 15727060112 | yutianchun2007@126.com | China | 9855 | 58 |
| Henan Weitixi Chemical Technology Co., Ltd | 0371-53370800 18037197114 | 3807961510@qq.com | China | 9933 | 58 |
| Shanghai Titan Scientific Co.,Ltd | 18616708014 | yhx@titansci.com | China | 9998 | 58 |
| TLC Pharmaceutical Standards Ltd. | 18012923235 | chinasales04@tlcstandards.com.cn | China | 8290 | 58 |
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