Romosozumab
- CAS No.
- 909395-70-6
- Chemical Name:
- Romosozumab
- Synonyms
- AMG785;AMG 785;AMG-785;CDP7851;CDP-7851;CDP 7851;Romosozumab;Research Grade Romosozumab;Romosozumab - Osteoporosis;Research Grade Romosozumab(DHJ48701)
- CBNumber:
- CB54805794
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Romosozumab | CLA1292 | 1mg | $937.5 |
| Romosozumab | CLA1292 | 2mg | $1500 |
| Romosozumab | CLA1292 | 5mg | $1875 |
| Romosozumab | CLA1292 | 10mg | $2500 |
| Romosozumab | CLA1292 | 25mg | $3125 |
| form | Liquid |
|---|---|
| color | Colorless to light yellow |
| FDA UNII | 3VHF2ZD92J |
| ATC code | M05BX06 |
Romosozumab price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CLA1292 | Romosozumab | 909395-70-6 | 1mg | $937.5 | 2026-06-04 | Buy |
| Biosynth | CLA1292 | Romosozumab | 909395-70-6 | 2mg | $1500 | 2026-06-04 | Buy |
| Biosynth | CLA1292 | Romosozumab | 909395-70-6 | 5mg | $1875 | 2026-06-04 | Buy |
| Biosynth | CLA1292 | Romosozumab | 909395-70-6 | 10mg | $2500 | 2026-06-04 | Buy |
| Biosynth | CLA1292 | Romosozumab | 909395-70-6 | 25mg | $3125 | 2026-06-04 | Buy |
Romosozumab Chemical Properties,Uses,Production
Uses
Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis[1][2].
in vivo
Romosozumab (30 mg/kg; s.c. twice a week for 10 weeks) converts trabecular rods into trabecular plates in cynomolgus monkeys[1]. Romosozumab (3 and 30 mg/kg; s.c. once a week for 6 or 12 months) improves bone mass, architecture, and bone strength, and maintains bone quality at the same time in mature cynomolgus monkeys with 4 months post-ovariectomy[2].
| Animal Model: | Male cynomolgus monkeys[1] |
| Dosage: | 30 mg/kg |
| Administration: | Subcutaneous injection; 30 mg/kg twice a week for 10 weeks |
| Result: | Increased bone formation and plate-like trabecular morphology, and improved mechanical performance. |
References
[1] Paik J, Scott LJ. Romosozumab: A Review in Postmenopausal Osteoporosis. Drugs Aging. 2020 Nov;37(11):845-855. DOI:10.1007/s40266-020-00793-8
[2] Ominsky MS, et al. Romosozumab Improves Bone Mass and Strength While Maintaining Bone Quality in Ovariectomized Cynomolgus Monkeys. J Bone Miner Res. 2017 Apr;32(4):788-801. DOI:10.1002/jbmr.3036
Romosozumab Preparation Products And Raw materials
Raw materials
Preparation Products
Romosozumab Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19936 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8615965530500 | nickzhang@hangyubiotech.com | China | 9946 | 58 |
| Wuhan Fortuna Chemical Co.,Ltd | +86-2759207851; +8618007136271 | hk@fortunachem.com | China | 6006 | 58 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Tianjin Kaifu Pharmaceutical Technology Co., Ltd. | 18081075745 | chemflowtech@sina.com | China | 1886 | 58 |
| Guangzhou Hongyuan Chemical Co.,Ltd | 15817493340 | 981810490@qq.com | China | 1566 | 58 |
| Wuhan Chemstan Biotechnology Co., Ltd. | 027-65317797 15926423062 | 422450190@qq.com | China | 10308 | 58 |
| Bide Pharmatech Ltd. | 400-1647117 13681763483 | product02@bidepharm.com | China | 59936 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24958 | 58 |
| Biolab Reagents | 027-65279366 18108604356 | products@biolabreagent.com | China | 9865 | 58 |
