PORPHOBILINOGEN
- CAS No.
- 487-90-1
- Chemical Name:
- PORPHOBILINOGEN
- Synonyms
- PBG;PORPHOBILINOGEN;porphobilinogen (synth.);5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid;5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci;5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid;5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID;1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid;3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
- CBNumber:
- CB5481219
- Molecular Formula:
- C10H14N2O4
- Molecular Weight:
- 226.23
- MDL Number:
- MFCD00005224
- MOL File:
- 487-90-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Porphobilinogen powder | P1134 | 1mg | $125 |
| Porphobilinogen powder | P1134 | 5mg | $415 |
| Porphobilinogen >95%(HPLC) | TRC-P689500-5MG | 5mg | $376 |
| Porphobilinogen >95%(HPLC) | TRC-P689500-10MG | 10mg | $737 |
| Porphobilinogen 99% | CS-W014211 | 1mg | $352 |
| More product size | |||
| Melting point | 174-177℃ |
|---|---|
| Boiling point | 479℃ |
| Density | 1.421 |
| Flash point | 243℃ |
| storage temp. | -20°C |
| solubility | Aqueous Base (Slightly), Acetonitrile (Slightly), DMSO (Slightly) |
| pka | 4.22±0.10(Predicted) |
| form | powder |
| color | light yellow to pink |
| Merck | 13,7681 |
| BRN | 220051 |
| InChI | 1S/C10H14N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5,12H,1-4,11H2,(H,13,14)(H,15,16) |
| InChIKey | QSHWIQZFGQKFMA-UHFFFAOYSA-N |
| SMILES | NCc1[nH]cc(CCC(O)=O)c1CC(O)=O |
| FDA UNII | 74KHC72QXK |
| EPA Substance Registry System | Porphobilinogen (487-90-1) |
| UNSPSC Code | 12352204 |
| NACRES | NA.83 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 8-10 |
| TSCA | TSCA listed |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
PORPHOBILINOGEN price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P1134 | Porphobilinogen powder | 487-90-1 | 1mg | $125 | 2026-04-30 | Buy |
| Sigma-Aldrich | P1134 | Porphobilinogen powder | 487-90-1 | 5mg | $415 | 2026-04-30 | Buy |
| TRC | TRC-P689500-5MG | Porphobilinogen >95%(HPLC) | 487-90-1 | 5mg | $376 | 2026-06-03 | Buy |
| TRC | TRC-P689500-10MG | Porphobilinogen >95%(HPLC) | 487-90-1 | 10mg | $737 | 2026-06-03 | Buy |
| ChemScene | CS-W014211 | Porphobilinogen 99% | 487-90-1 | 1mg | $352 | 2026-06-04 | Buy |
PORPHOBILINOGEN Chemical Properties,Uses,Production
Uses
An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria.
Definition
ChEBI: Porphobilinogen is a dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively. It has a role as a metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of pyrroles, a dicarboxylic acid and an aralkylamino compound. It is a conjugate acid of a porphobilinogen(1-).
Biochem/physiol Actions
Intermediate in the biosynthesis of heme.
IC 50
Human Endogenous Metabolite
Purification Methods
Porphobilinogen recrystallises as the monohydrate (pink crystals) from dilute NH4 OAc solutions of pH 4, and is dried in vacuo. The hydrochloride monohydrate has m 165-170o(dec) (from dilute HCl). [Jackson & MacDonald Can J Chem 35 715 1957, Westall Nature 170 614 1952, Bogarad J Am Chem Soc 75 3610 1953, Beilstein 22/14 V 210.]
PORPHOBILINOGEN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc. | 28-85305008 | CHINA | 964 | 58 | |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
| GLR Innovations | -- | info@glrgroup.in | India | 4535 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | 18143011203 | info@chemextension.com | China | 42056 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemsky (shanghai) International Co.,Ltd | 021-50135380 | shchemsky@sina.com | China | 15402 | 60 |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14435 | 57 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8065 | 58 |
| Chengdu Aslee Biopharmaceuticals, Inc | 028-85305008 02885305008 | 2306208234@qq.com | China | 1006 | 50 |
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