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ChemicalBook >> CAS DataBase List >>Hyaluronidase

Hyaluronidase

CAS No.
37326-33-3
Chemical Name:
Hyaluronidase
Synonyms
HYALURONATE 4-GLYCANOHYDROLASE;Hydase;Hyalosidase;HYALURONOGLUCOSAMINIDASE;Hyaluronidase - CAS 37326-33-3 - Calbiochem;Hylenex;vitaminase;EC 4.2.99.1;EC 3.2.1.35;ovinetestes
CBNumber:
CB5486087
Molecular Formula:
NULL
Molecular Weight:
0
MDL Number:
MFCD00131351
MOL File:
Mol file
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-15 20:54:36
Product description Number Pack Size Price
Hyaluronidase HX0514 1PKG $281
Hyaluronidase from bovine testes Type VI-S, lyophilized powder, 3,000-15,000?units/mg solid H3631 3000units $177
Hyaluronidase from bovine testes Type VI-S, lyophilized powder, 3,000-15,000?units/mg solid H3631 15000Units $512
Hyaluronidase from bovine testes Type VI-S, lyophilized powder, 3,000-15,000?units/mg solid H3631 30000units $960
Hyaluronidase 389561 100u $195
More product size

Hyaluronidase Properties

storage temp. -20°C
solubility Soluble in water, practically insoluble in acetone and in anhydrous ethanol
form powder
color yellow-brown
biological source sheep testis
Water Solubility 0.5 M acetate, pH 6.0: 30U/mL
water: 30U/mL
Specific Activity 750-3000units/mg solid
Major Application diagnostic assay manufacturing
Cosmetics Ingredients Functions SKIN CONDITIONING
EWG's Food Scores 1
NCI Dictionary of Cancer Terms hyaluronidase
FDA UNII 8KOG53Z5EM
ATC code B06AA03
UNSPSC Code 12352204
NACRES NA.78

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  22-24/25
WGK Germany  3
3-10
HS Code  35079090
Storage Class 11 - Combustible Solids
Hazard Classifications Resp. Sens. 1

Hyaluronidase price More Price(72)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich HX0514 Hyaluronidase 37326-33-3 1PKG $281 2026-04-30 Buy
Sigma-Aldrich H3631 Hyaluronidase from bovine testes Type VI-S, lyophilized powder, 3,000-15,000?units/mg solid 37326-33-3 3000units $177 2026-04-30 Buy
Sigma-Aldrich H3631 Hyaluronidase from bovine testes Type VI-S, lyophilized powder, 3,000-15,000?units/mg solid 37326-33-3 15000Units $512 2026-04-30 Buy
Sigma-Aldrich H3631 Hyaluronidase from bovine testes Type VI-S, lyophilized powder, 3,000-15,000?units/mg solid 37326-33-3 30000units $960 2026-04-30 Buy
Sigma-Aldrich 389561 Hyaluronidase 37326-33-3 100u $195 2026-04-30 Buy
Product number Packaging Price Buy
HX0514 1PKG $281 Buy
H3631 3000units $177 Buy
H3631 15000Units $512 Buy
H3631 30000units $960 Buy
389561 100u $195 Buy

Hyaluronidase Chemical Properties,Uses,Production

Chemical Properties

White or yellowish-white, amorphous powder.

Uses

Used to promote absorption of fluid into tissues.

Uses

Hyaluronidase from sheep testes has been used:

  • in flow cytometry
  • in the isolation of putative spermatogonial stem cells (SSCs)
  • to study the effects of magnetic stimulation in magnetic hydrogel properties
  • in immunohistochemistry to visualize collagen type II distribution
  • to expose group-III auditory neurons of Muller′s organ for patch-clamp recordings
  • for the degeneration of hydrogels

Definition

Any of a class of soluble enzymes produced in mammalian testes that catalyze cleavage of glycosidic bonds of oartucular mucopolysaccharides. As a component of venoms, it reduces the viscosity of connective tissues and promotes tissue penetration of the ve

General Description

Hyaluronidase is a hyaluronic acid-metabolizing enzyme. It is found in the venoms of snake, honeybee and hymenoptera. Hyaluronidase degrades hyaluronic acid (HA), which enhances membrane permeability, lowers viscosity and increases tissue permeability. It enhances the diffusion of local anesthetics, lowers the size of myocardial infarction, improves the effects of anticancer drugs and prevents perineal trauma during spontaneous delivery.

Biochem/physiol Actions

Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression.

Purification Methods

Hyaluronidase is purified by chromatography on DEAE-cellulose prior to use. [Distler & Jourdain J Biol Chem 248 6772 1973.]

Description

Hyaluronidase is a glycoprotein isolated from bovine testes that degrades hyaluronan (HA) polymers. This enzyme hydrolyzes the endo-N-acetylhexosaminic bonds of hyaluronic acid, chondroitinsulfuric acid A, and chondroitinsulfuric acid C to tetrasaccharide rich oligosaccharides. Studies have shown that hyaluronidases have the potential for clinical utility as both biomarkers and therapeutic targets when looking at a variety of cancers. Hyaluronidase is an effective enzyme for tissue dissociation.

Source

Bovine

Hyaluronidase Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 317)Suppliers
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BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 480 58
career henan chemical co
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BOC Sciences
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CONIER CHEM AND PHARMA LIMITED
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Creative Enzymes
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TargetMol Chemicals Inc.
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ANHUI WITOP BIOTECH CO., LTD
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RongNa Biotechnology Co.,Ltd
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Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1059@dideu.com China 29093 58

View Lastest Price from Hyaluronidase manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Hyaluronidase pictures 2026-08-01 Hyaluronidase
37326-33-3
0.99 RongNa Biotechnology Co.,Ltd
Hyaluronidase pictures 2026-07-15 Hyaluronidase
37326-33-3
$41.00-80.00 10g TargetMol Chemicals Inc.
Hyaluronidase pictures 2026-05-22 Hyaluronidase
37326-33-3
10g ≥300iu/mg; ≥500iu/mg 5000 g BINBO BIOLOGICAL CO.,LTD
  • Hyaluronidase pictures
  • Hyaluronidase
    37326-33-3
  • $0.00
  • ≥300iu/mg; ≥500iu/mg
  • BINBO BIOLOGICAL CO.,LTD
HYALURONATE GLYCANOHYDROLASE HYALURONIDASE BOVINE TESTES HYALURONIDASE OVINE TESTES HYALURONIDASE, SALT-FREE, BOVINE HYALURONIDASE, STREPTOMYCES HYALURONLYTICUS NOV SPECIES HYALURONIDASE TYPE II HYALURONIDASE TYPE III HYALURONIDASE TYPE I-S HYALURONIDASE TYPE IV-S HYALURONIDASE TYPE V HYALURONIDASE TYPE VIII HYALURONIDASE TYPE VI-S HYALURONOGLUCOSAMINIDASE TYPE II HYALURONOGLUCOSAMINIDASE TYPE III HYALURONOGLUCOSAMINIDASE TYPE I-S HYALURONOGLUCOSAMINIDASE TYPE IV-S HYALURONOGLUCOSAMINIDASE TYPE V HYALURONOGLUCOSAMINIDASE TYPE VIII HYALURONOGLUCOSAMINIDASE TYPE VI-S EC 4.2.99.1 EC 3.2.1.35 EC: 3.2.1.35 EC 3.2.1.35 TYPE II EC 3.2.1.35 TYPE I-S EC 3.2.1.35 TYPE IV-S EC 3.2.1.35 TYPE V EC 3.2.1.35 TYPE VIII EC 3.2.1.35 TYPE VI-S EC: 3.1.2.35 Hyaluronidase from sheep testes Hyaluronidase from bovine testes,Hyaluronate 4-glycanohydrolase, Hyaluronoglucosaminidase Hyaluronidase from ovine testes, lyophil. Hyaluronidase froM ovine testes Min. 1 000 U/Mg lyophil. Hyaluronidase froMthe testes Hyaluronidase from bovine testes Vetec(TM) reagent grade Hyaluronidasefrombovinetestes(Purified) HYALURONATE 4-GLYCANOHYDROLASE TYPE VIII HYALURONATE 4-GLYCANOHYDROLASE TYPE VI-S HYALURONATE 4-GLYCANOHYDROLASE TYPE II HYALURONATE 4-GLYCANOHYDROLASE TYPE III HYALURONATE 4-GLYCANOHYDROLASE TYPE I-S HYALURONATE 4-GLYCANOHYDROLASE TYPE IV-S HYALURONATE 4-GLYCANOHYDROLASE TYPE V HYALURONIDASE FROM BOVINE TESTES, ~0.1 U /MG HYALURONIDASE TYPE I-S FROM*BOVINE TESTE S HYALURONIDASE TYPE IV-S FROM BOVINE*TEST ES EMBRYO T HYALURONIDASE TYPE V FROM SHEEP TESTES HYALURONIDASE TYPE VIII*FROM BOVINE TEST ES HYALURONIDASE FROM OVINE TESTES, LYOPH., ~0.25 U/MG HYALURONIDASE TYPE IV-S FROM*BOVINE TEST ES HYALURONIDASE FROM SHEEP TESTES, LYOPH., ST.-FR.,~0.02 U/MG* HYALURONIDASE TYPE II FROM SHEEP TESTES HyaluronidaseExLeech(E.C.3.2.1.3.6) Hyaluronidasefrombovinetestes ovinetestes Hyaluronidase from ovine testes min. 1 000 U/mg Chondroitinase Hyaluronoglucosidase
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