3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE
- CAS No.
- 74885-09-9
- Chemical Name:
- 3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE
- Synonyms
- 5-CT;5-CAT;5-carboxamidotryptamine;2-Carboxyamidotryptamine;5-Carboxamide tryptamine;5-Carboxyamidotryptamine;5-CARBOXAMINODOTRYPTAMINE;5-Carboxamidotryptamine, 5-CT;3-(2-Aminoethyl)-1H-indole-5-carboxamide;1H-Indole-5-carboxamide, 3-(2-aminoethyl)-
- CBNumber:
- CB5487413
- Molecular Formula:
- C11H13N3O
- Molecular Weight:
- 203.24
- MDL Number:
- MFCD02258957
- MOL File:
- 74885-09-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 5-Carboxamidotryptamine | FA162449 | 100mg | $3149 |
| 5-Carboxamidotryptamine 98.74% | CS-0113459 | 5mg | $309 |
| 5-Carboxamidotryptamine 98.74% | CS-0113459 | 10mg | $487 |
| 5-Carboxamidotryptamine 98.74% | CS-0113459 | 5mg | $309 |
| 5-Carboxamidotryptamine 98.74% | CS-0113459 | 10mg | $487 |
| Boiling point | 513.6±35.0 °C(Predicted) |
|---|---|
| Density | 1.293±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | H2O: 10 mg/mL |
| pka | 16.32±0.30(Predicted) |
| form | solid |
| color | white or off-white |
| Stability | Hygroscopic |
| EWG's Food Scores | 1 |
| FDA UNII | 91H76044O0 |
3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | FA162449 | 5-Carboxamidotryptamine | 74885-09-9 | 100mg | $3149 | 2026-06-04 | Buy |
| ChemScene | CS-0113459 | 5-Carboxamidotryptamine 98.74% | 74885-09-9 | 5mg | $309 | 2026-06-04 | Buy |
| ChemScene | CS-0113459 | 5-Carboxamidotryptamine 98.74% | 74885-09-9 | 10mg | $487 | 2026-06-04 | Buy |
| ChemScene | CS-0113459 | 5-Carboxamidotryptamine 98.74% | 74885-09-9 | 5mg | $309 | 2026-06-04 | Buy |
| ChemScene | CS-0113459 | 5-Carboxamidotryptamine 98.74% | 74885-09-9 | 10mg | $487 | 2026-06-04 | Buy |
3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Chemical Properties,Uses,Production
Uses
5-Carboxamidotryptamine maleate is an agonist of the 5-HT1 receptors.
Definition
ChEBI: 5-carboxamidotryptamine is a member of tryptamines.
in vivo
5-Carboxamidotryptamine (0.03-3 mg/kg i.p. and 0.125-5 μg i.c.v.) causes a dose-dependent reduction in rectal temperature of mice[3].
5-Carboxamidotryptamine (0.1-1 mg/kg; i.p.) reduces rectal temperature in wild type mice but not 5-HT7 receptor knockout mice[3].
5-Carboxamidotryptamine (0.0 1-1 μg/kg; i.v.) causes consistent, dose-related decreases in diastolic blood pressure and carotid arterial vascular resistance and increases in heart rate of cats. In contrast, 5-HT (1-100 μg/kg; i.v.) causes tachycardia but variable and complex effects on diastolic blood pressure and carotid arterial vascular resistance[5].
5-Carboxamidotryptamine does not cause bronchoconstriction in cats. In contrast, 5-HT causes dose-related bronchoconstriction[5].
| Animal Model: | Male Swiss Webster mice (20-25 g)[3] |
| Dosage: | 0.03-3 mg/kg (i.p.) and 0.125-5 μg (i.c.v.) |
| Administration: | i.p. and i.c.v. |
| Result: | Caused dose-dependent reduction in rectal temperature. |
| Animal Model: | 5-HT7 receptor knockout mice (background=50% 129SvEv/50% C57Bl/6J)[3] |
| Dosage: | 0.1-1 mg/kg |
| Administration: | i.p. and i.c.v. |
| Result: | Reduced rectal temperature in wild type but not 5-HT7 receptor knockout mice. |
IC 50
5-HT1A Receptor; 5-HT1B Receptor; 5-HT1D Receptor; 5-HT5A Receptor; 5-HT7 Receptor
3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
3-(2-AMINO-ETHYL)-1H-INDOLE-5-CARBOXYLIC ACID AMIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53803 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4849 | 55 | |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8447 | 60 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44918 | 58 |
| Aikon International Limited | 025-58859352 18651614124 | 2881516338@qq.com | China | 10000 | 58 |
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6051 | 58 |
| Santa Cruz Biotechnology Inc | -- | scbt@scbt.com | China | 6594 | 58 |
