5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
![5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Structure](CAS/GIF/885-70-1.gif)
- CAS No.
- 885-70-1
- Chemical Name:
- 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
- Synonyms
- 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;LS 75;Pirenzepine EP Impurity B;11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one;5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE;5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one;1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro-
- CBNumber:
- CB5488339
- Molecular Formula:
- C12H9N3O
- Molecular Weight:
- 211.22
- MDL Number:
- MFCD00190169
- MOL File:
- 885-70-1.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | TRC-D446720-2.5G | 2.5g | $145 |
| 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | TRC-D446720-1G | 1g | $82 |
| 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Asreported | 161990 | 2.5g | $403 |
| LS-75 ≥98% | CS-0213333 | 5g | $109 |
| LS-75 ≥98% | CS-0213333 | 25g | $376 |
| More product size | |||
| Melting point | 292-293℃ |
|---|---|
| Boiling point | 336℃ |
| Density | 1.275 |
| Flash point | 157℃ |
| storage temp. | Refrigerator, under inert atmosphere |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
| form | Solid |
| pka | 11.58±0.20(Predicted) |
| color | Light Beige to Beige |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| REACH Registrations | Active |
5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-D446720-2.5G | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | 885-70-1 | 2.5g | $145 | 2026-06-03 | Buy |
| TRC | TRC-D446720-1G | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one | 885-70-1 | 1g | $82 | 2026-06-03 | Buy |
| Usbiological | 161990 | 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one Asreported | 885-70-1 | 2.5g | $403 | 2026-06-03 | Buy |
| ChemScene | CS-0213333 | LS-75 ≥98% | 885-70-1 | 5g | $109 | 2026-06-04 | Buy |
| ChemScene | CS-0213333 | LS-75 ≥98% | 885-70-1 | 25g | $376 | 2026-06-04 | Buy |
5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Chemical Properties,Uses,Production
Chemical Properties
Light yellow crystals. Melting point 283-285℃ (286-288℃).
Uses
5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, can be used in the synthesis of fluorescent pirenzepine derivatives, used as potential bitopic ligands of the Human M1 Muscarinic receptor.
Synthesis
In a 1000 ml reaction flask,Add 600 ml of butanol,100 g of 2-amino-N- (2-chloropyridyl-3-yl) benzamide,2 ml of concentrated sulfuric acid,The reaction was refluxed for 3 hours at a reaction temperature of 80 C,Cooled to room temperature,filter,Washed with acetone,50-60 C in vacuo to give 98 g of a pale yellow solid product,Yield 98percent, purity 99percent.
References
[1] Patent: CN106432227, 2017, A. Location in patent: Paragraph 0019; 0020
[2] Journal of Medicinal Chemistry, 2004, vol. 47, # 17, p. 4300 - 4315
[3] Journal of Medicinal Chemistry, 1993, vol. 36, # 15, p. 2107 - 2114
[4] Collection of Czechoslovak Chemical Communications, 1988, vol. 53, # 8, p. 1820 - 1844
[5] Patent: WO2006/8118, 2006, A1. Location in patent: Page/Page column 20
5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29792 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14304 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19987 | 58 |
| Shanghai Quedan biology science and technology co., ltd | +86-13004146052 | lnzc@quedan.com.cn | China | 1022 | 58 |
View Lastest Price from 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-15 | 2-CHLORO-4-FLUORO-5-METHYL ANILINE
116759-33-2
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co | |
![5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE pictures](https://img.chemicalbook.com/ProductImageEN/2020-1/Small/fb19b4d1-f8e3-49a4-96ba-0a3df52a1d53.png) |
2020-01-15 | 5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE
885-70-1
|
$1.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- 2-CHLORO-4-FLUORO-5-METHYL ANILINE
116759-33-2
- $1.00
- 99%
- Career Henan Chemical Co
-
- 5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE
885-70-1
- $1.00
- 99%
- Career Henan Chemical Co
885-70-1(5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one)Related Search:
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