L-glutamic acid, compound with erythromycin (1:1)
- CAS No.
- 16667-03-1
- Chemical Name:
- L-glutamic acid, compound with erythromycin (1:1)
- Synonyms
- L-glutamic acid, compound with erythromycin (1:1)
- CBNumber:
- CB5884827
- Molecular Formula:
- C37H67NO13.C5H9NO4
- Molecular Weight:
- 881.059
- MDL Number:
- MOL File:
- 16667-03-1.mol
- MSDS File:
- SDS
L-glutamic acid, compound with erythromycin (1:1) Chemical Properties,Uses,Production
Description
Erythromycin glutamate is a macrolide bacteriostatic antibiotic often used in Serbia, especially in the treatment of respiratory infections. This antibiotic is metabolized through the liver and inhibits cytochrome enzyme P450A (CYP) 3A41. _x000D_ .
Uses
Erythromycin glutamate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin glutamate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin glutamate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
References
[1] Gribble MJ, et al. Erythromycin. Med Clin North Am. 1982 Jan;66(1):79-89. DOI:10.1016/s0025-7125(16)31443-2
[2] Nakornchai S, et al. Activity of azithromycin or erythromycin in combination with antimalarial drugs against multidrug-resistant Plasmodium falciparum in vitro. Acta Trop. 2006 Dec;100(3):185-91. Epub 2006 Nov 28. DOI:10.1016/j.actatropica.2006.10.008
[3] Hamada K, et al. Antitumor effect of erythromycin in mice. Chemotherapy. 1995 Jan-Feb. 41(1):59-69. DOI:10.1159/000239325
[4] Katayama Y, et al. Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. Brain Res. 2014 Nov 7. 1588:159-67. DOI:10.1016/j.brainres.2014.09.016
L-glutamic acid, compound with erythromycin (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
L-glutamic acid, compound with erythromycin (1:1) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 029-63373950 17392216152 | 1050@dideu.com | China | 9998 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29867 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| BOC Sciences | 58 |
| Shaanxi Dideu Newmaterial Co., Ltd. | 58 |
| TargetMol Chemicals Inc. | 58 |
