4-hydroxy-2-Piperidinone
- CAS No.
- 476014-76-3
- Chemical Name:
- 4-hydroxy-2-Piperidinone
- Synonyms
- 4-hydroxy-2-Piperidi;4-Hydroxy-2-piperidone;4-hydroxy-2-Piperidinone;4-Hydroxy-piperidin-2-one;2-Piperidinone, 4-hydroxy-;2-Piperidinone, 4-hydroxy- 95%min
- CBNumber:
- CB5958436
- Molecular Formula:
- C5H9NO2
- Molecular Weight:
- 115.13
- MDL Number:
- MFCD09743648
- MOL File:
- 476014-76-3.mol
| Product description | Number | Pack Size | Price |
| 4-Hydroxy-2-piperidinone | TRC-H950875-250MG | 250mg | $205 |
| 4-Hydroxy-2-piperidinone Asreported | 161406 | 250mg | $531 |
| 4-Hydroxy-2-piperidinone | TRC-H950875-2.5G | 2.5g | $1611 |
| 4-HYDROXY-2-PIPERIDINONE 97% | 68726 | 0.25G | $34 |
| 4-HYDROXY-2-PIPERIDINONE 97% | 68726 | 1G | $69 |
| More product size | |||
| Melting point | 165-168°C |
|---|---|
| Boiling point | 352.3±35.0 °C(Predicted) |
| Density | 1.199±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Methanol (Slightly, Sonicated) |
| pka | 14.01±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C5H9NO2/c7-4-1-2-6-5(8)3-4/h4,7H,1-3H2,(H,6,8) |
| InChIKey | PRCAKTIAKXMBQF-UHFFFAOYSA-N |
| SMILES | N1CCC(O)CC1=O |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
4-hydroxy-2-Piperidinone price More Price(55)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-H950875-250MG | 4-Hydroxy-2-piperidinone | 476014-76-3 | 250mg | $205 | 2026-06-03 | Buy |
| Usbiological | 161406 | 4-Hydroxy-2-piperidinone Asreported | 476014-76-3 | 250mg | $531 | 2026-06-03 | Buy |
| TRC | TRC-H950875-2.5G | 4-Hydroxy-2-piperidinone | 476014-76-3 | 2.5g | $1611 | 2026-06-03 | Buy |
| AstaTech | 68726 | 4-HYDROXY-2-PIPERIDINONE 97% | 476014-76-3 | 0.25G | $34 | 2026-04-30 | Buy |
| AstaTech | 68726 | 4-HYDROXY-2-PIPERIDINONE 97% | 476014-76-3 | 1G | $69 | 2026-04-30 | Buy |
4-hydroxy-2-Piperidinone Chemical Properties,Uses,Production
Uses
4-Hydroxy-2-piperidinone is a synthetic intermediate in the synthesis of pharmaceutical goods.
Synthesis
50607-30-2
476014-76-3
Step 1) NaBH4 (1 g, 26.55 mmol) was slowly added to a solution of piperidine-2,4-dione (1 g, 8.8 mmol) in methanol (25 mL) at 0°C. The reaction mixture was stirred at room temperature overnight before the solvent was removed by distillation under reduced pressure. The residue was purified by silica gel column chromatography (eluent: dichloromethane/methanol, 5:1, v/v) to afford 4-hydroxy-2-piperidone as a yellow solid (960 mg, 87% yield). m/z by LC-MS (ESI, positive ion mode): 138 [M + Na]+.
References
[1] Patent: WO2013/138210, 2013, A1. Location in patent: Paragraph 0258
[2] Patent: EP2947085, 2015, A1. Location in patent: Paragraph 0238; 0239; 0240
4-hydroxy-2-Piperidinone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chembon Pharmaceutical Co., Ltd. | +86-28-8425-2981 | CHINA | 722 | 55 | |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52704 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9653 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
View Lastest Price from 4-hydroxy-2-Piperidinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 4-hydroxy-2-Piperidinone
476014-76-3
|
$1.00 | 1kg | 98% | 200kg | Career Henan Chemical Co |
-
- 4-hydroxy-2-Piperidinone
476014-76-3
- $1.00
- 98%
- Career Henan Chemical Co
