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ChemicalBook >> CAS DataBase List >>Miltrione

Miltrione

CAS No.
27210-57-7
Chemical Name:
Miltrione
Synonyms
Rosmariquinone;C13715;Miltiron;NSC 639662;minestrone;Miltrione USP/EP/BP;8,8-DIMETHYL-2-PROPAN-2-YL-6,7-DIHYDRO-5H-PHENANTHRENE-3,4-DIONE;5,6,7,8-Tetrahydro-2-isopropyl-8,8-diMethyl-3,4-phenanthrenedione;5,6,7,8-Tetrahydro-8,8-dimethyl-2-isopropyl-3,4-phenanthrenedione;2-Isopropyl-5,6,7,8-tetrahydro-8,8-dimethylphenanthrene-3,4-dione
CBNumber:
CB61074910
Molecular Formula:
C19H22O2
Molecular Weight:
282.38
MDL Number:
MFCD00238644
MOL File:
27210-57-7.mol
MSDS File:
SDS
Last updated:2026-06-17 18:53:45
Product description Number Pack Size Price
Miltirone ≥95% 36663 1mg $61
Miltirone ≥95% 36663 5mg $283
Miltirone ≥95% 36663 10mg $504
Miltirone 282893 5mg $495
Miltirone 282893 10mg $779
More product size

Miltrione Properties

Melting point 98-100℃ (hexane )
Boiling point 421.6±45.0 °C(Predicted)
Density 1.094±0.06 g/cm3 (20 ºC 760 Torr)
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form powder
color Red
LogP 4.916 (est)

Miltrione price More Price(55)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 36663 Miltirone ≥95% 27210-57-7 1mg $61 2026-04-30 Buy
Cayman Chemical 36663 Miltirone ≥95% 27210-57-7 5mg $283 2026-04-30 Buy
Cayman Chemical 36663 Miltirone ≥95% 27210-57-7 10mg $504 2026-04-30 Buy
Usbiological 282893 Miltirone 27210-57-7 5mg $495 2026-06-03 Buy
Usbiological 282893 Miltirone 27210-57-7 10mg $779 2026-06-03 Buy
Product number Packaging Price Buy
36663 1mg $61 Buy
36663 5mg $283 Buy
36663 10mg $504 Buy
282893 5mg $495 Buy
282893 10mg $779 Buy

Miltrione Chemical Properties,Uses,Production

Chemical Properties

Orange granular crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Salvia miltiorrhiza.

Uses

An active component in Salvia miltiorrhiza that has been shown to inhibit the increase in the abundance of the mRNA for the α4 subunit of the GABAA receptor induced by ethanol withdrawal in cultured hippocampal neurons. A potential phytotherapeutic agent in the treatment of alcohol dependence.

Definition

ChEBI: Miltirone is an abietane diterpenoid.

in vivo

Miltirone (10-60 mg/kg, p.o.; one hour before test) increases the number of punished crossings in the four-plate test in mice[1].

Animal Model:Mice[1]
Dosage:10, 30, 60 mg/kg
Administration:Oral gavage (p.o.); an hour before test
Result:Increased the number of punished crossings of mice in the 'Four-Plate Test'.
Showed some reversal of the effect of diazepam as expected for a partial agonist.
Produced no muscle relaxant effect and did not impair the performance of mice in the Julou-Courvoisier horizontal wire test.

IC 50

CES2: 0.04 μM (Ki)

88-69-7
27210-57-7
Synthesis of Miltrione from 2-Isopropylphenol
Global( 140)Suppliers
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Shanghai Zheyan Biotech Co., Ltd.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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View Lastest Price from Miltrione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Miltrione pictures 2026-06-30 Miltrione
27210-57-7
1KG 98% 1000kgs Shaanxi Dideu New Materials Co. Ltd
Miltrione pictures 2020-02-17 Miltrione
27210-57-7
$7.00 1KG 99% 100KG Career Henan Chemical Co
  • Miltrione pictures
  • Miltrione
    27210-57-7
  • $0.00
  • 98%
  • Shaanxi Dideu New Materials Co. Ltd
  • Miltrione pictures
  • Miltrione
    27210-57-7
  • $7.00
  • 99%
  • Career Henan Chemical Co

Miltrione Spectrum

5,6,7,8-Tetrahydro-2-isopropyl-8,8-diMethyl-3,4-phenanthrenedione 5,6,7,8-Tetrahydro-8,8-diMethyl-2-(1-Methylethyl)-3,4-phenanthrenedione 2-Isopropyl-5,6,7,8-tetrahydro-8,8-dimethylphenanthrene-3,4-dione 5,6,7,8-Tetrahydro-8,8-dimethyl-2-isopropyl-3,4-phenanthrenedione C13715 Miltiron NSC 639662 3,4-Phenanthrenedione,5,6,7,8-tetrahydro-8,8-dimethyl-2-(1-methylethyl)- 8,8-DIMETHYL-2-PROPAN-2-YL-6,7-DIHYDRO-5H-PHENANTHRENE-3,4-DIONE Miltrione USP/EP/BP minestrone Rosmariquinone 2-Isopropyl-8,8-dimethyl-5,6,7,8-tetrahydrophenanthrene-3,4-dione Gamma-aminobutyric acid Receptor,inhibit,acid,γ-Aminobutyric acid Receptor,GABA Receptor,neurotransmission,Miltirone,GABA,γ-aminobutyric,Inhibitor 27210-57-7 Miscellaneous Natural Products Aromatics Inhibitors Intermediates & Fine Chemicals Pharmaceuticals
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