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ChemicalBook >> CAS DataBase List >>3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE

3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE

CAS No.
1192-80-9
Chemical Name:
3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE
Synonyms
1,2,4-Oxadiazole, 3-(chloroMethyl)-5-Methyl-;3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98%;3-(chloromethyl)-5-methyl-1,2,4-oxadiazole(SALTDATA: FREE)
CBNumber:
CB61092558
Molecular Formula:
C4H5ClN2O
Molecular Weight:
132.55
MDL Number:
MFCD01809083
MOL File:
1192-80-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 01:59:46
Product description Number Pack Size Price
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% AS42625 1g $85
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% AS42625 5g $265
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% AS42625 25g $1007
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 95% OR300629 1g $209
3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% C40128 250mg $105
More product size

3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE Properties

Boiling point 76-77 °C(Press: 15 Torr)
Density 1.291±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
pka -1.10±0.32(Predicted)
form liquid
color Colourless

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HazardClass  IRRITANT
HS Code  2934999090

3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS42625 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% 1192-80-9 1g $85 2026-06-04 Buy
Activate Scientific AS42625 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% 1192-80-9 5g $265 2026-06-04 Buy
Activate Scientific AS42625 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% 1192-80-9 25g $1007 2026-06-04 Buy
Apolloscientific OR300629 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 95% 1192-80-9 1g $209 2026-06-04 Buy
Synthonix C40128 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% 1192-80-9 250mg $105 2026-05-06 Buy
Product number Packaging Price Buy
AS42625 1g $85 Buy
AS42625 5g $265 Buy
AS42625 25g $1007 Buy
OR300629 1g $209 Buy
C40128 250mg $105 Buy

3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE Chemical Properties,Uses,Production

Synthesis

Acetic anhydride

108-24-7

2-CHLORO-ACETAMIDE OXIME

3272-96-6

3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE

1192-80-9

2-Chloro-N'-hydroxyacetamidine (217 mg, 2 mmol) was mixed with ethanoic anhydride (224.4 mg, 2.2 mmol) in dichloromethane (2 mL) at room temperature and reacted for 1 hour. N,N-dimethylformamide (1 mL) was then added and the reaction mixture was heated at 130 °C for 2 hours. Upon completion of the reaction, the reaction was quenched with saturated sodium carbonate solution and extracted with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to afford the crude product 3-(chloromethyl)-5-methyl-1,2,4-oxadiazole (59 mg, 22.2% yield) as a yellow oil, which could be used in subsequent reactions without further purification.1H NMR (CDCl3, δ ppm): 4.41 (s, 2H), 2.55 (s, 3H).

References

[1] Patent: WO2004/14902, 2004, A2. Location in patent: Page 43
[2] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973, p. 2769 - 2772

3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 61)Suppliers
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3-(CHLOROMETHYL)-5-METHYL-1,2,4-OXADIAZOLE Spectrum

3-(chloromethyl)-5-methyl-1,2,4-oxadiazole(SALTDATA: FREE) 1,2,4-Oxadiazole, 3-(chloroMethyl)-5-Methyl- 3-(Chloromethyl)-5-methyl-1,2,4-oxadiazole 98% 1192-80-9
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