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ChemicalBook >> CAS DataBase List >>2,6-DICHLORO-4-NITROANISOLE

2,6-DICHLORO-4-NITROANISOLE

CAS No.
17742-69-7
Chemical Name:
2,6-DICHLORO-4-NITROANISOLE
Synonyms
NSC 212118;2,6-DICHLORO-4-NITROANISOLE;4-Nitro-2,6-dichloroanisole;1,3-Dichloro-2-Methoxy-5-Nitro;2,6-Dichloro-4-nitroanisole>2,6-DICHLORO-4-NITROANISOLE 99%;2,6-Dichloro-4-nitroanisole, 98%;3,5-Dichloro-4-methoxynitrobenzene;2.6-Dichlor-4-nitro-1-Methoxy-benzol;1,3-Dichloro-5-Methoxy-2-nitrobenzene
CBNumber:
CB6121226
Molecular Formula:
C7H5Cl2NO3
Molecular Weight:
222.03
MDL Number:
MFCD00061129
MOL File:
17742-69-7.mol
MSDS File:
SDS
Last updated:2026-05-28 01:56:16
Product description Number Pack Size Price
2,6-Dichloro-4-nitroanisole >98.0%(GC) D2872 1g $42
2,6-Dichloro-4-nitroanisole >98.0%(GC) D2872 5g $126
2,6-Dichloro-4-nitroanisole TRC-D438480-500MG 500mg $78
2,6-Dichloro-4-nitroanisole TRC-D438480-1G 1g $109
2,6-Dichloro-4-nitroanisole TRC-D438480-100MG 100mg $59
More product size

2,6-DICHLORO-4-NITROANISOLE Properties

Melting point 97-100 °C
Boiling point 305.6±37.0 °C(Predicted)
Density 1.5223 (rough estimate)
refractive index 1.6140 (estimate)
Flash point 160 °C
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Sparingly), Chloroform (Slightly)
form Solid
color Pale Yellow to Yellow
CAS DataBase Reference 17742-69-7(CAS DataBase Reference)
EWG's Food Scores 1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)Health Hazard (GHS08)Environment (GHS09)
GHS06,GHS08,GHS09
Signal word  Danger
Hazard statements  H301-H341-H411
Precautionary statements  P201-P202-P264-P270-P273-P280-P301+P310+P330-P308+P313-P391-P405-P501
Hazard Codes  N-T,T,N
Risk Statements  51/53-25
Safety Statements  61-45-36/37
RIDADR  2811
Hazard Note  Toxic
HazardClass  IRRITANT
PackingGroup  III
HS Code  29049095
REACH Registrations Inactive
NFPA 704
0
2 0

2,6-DICHLORO-4-NITROANISOLE price More Price(51)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical D2872 2,6-Dichloro-4-nitroanisole >98.0%(GC) 17742-69-7 1g $42 2026-04-30 Buy
TCI Chemical D2872 2,6-Dichloro-4-nitroanisole >98.0%(GC) 17742-69-7 5g $126 2026-04-30 Buy
TRC TRC-D438480-500MG 2,6-Dichloro-4-nitroanisole 17742-69-7 500mg $78 2026-06-03 Buy
TRC TRC-D438480-1G 2,6-Dichloro-4-nitroanisole 17742-69-7 1g $109 2026-06-03 Buy
TRC TRC-D438480-100MG 2,6-Dichloro-4-nitroanisole 17742-69-7 100mg $59 2026-06-03 Buy
Product number Packaging Price Buy
D2872 1g $42 Buy
D2872 5g $126 Buy
TRC-D438480-500MG 500mg $78 Buy
TRC-D438480-1G 1g $109 Buy
TRC-D438480-100MG 100mg $59 Buy

2,6-DICHLORO-4-NITROANISOLE Chemical Properties,Uses,Production

Chemical Properties

slightly beige crystals

Uses

2,6-Dichloro-4-nitroanisole can be used for thyroid hormone receptor agonists.

Synthesis Reference(s)

The Journal of Organic Chemistry, 28, p. 1656, 1963 DOI: 10.1021/jo01041a056

Synthesis

2,6-Dichloro-4-nitrophenol

618-80-4

Iodomethane

74-88-4

2,6-DICHLORO-4-NITROANISOLE

17742-69-7

GENERAL STEPS: To a stirred solution of 2,6-dichloro-4-nitrophenol (6.0 g, 28.84 mmol) in anhydrous DMF (60 mL) was added anhydrous K2CO3 (15.9 g, 115.36 mmol) and iodomethane (8.18 g, 57.69 mmol). The reaction mixture was stirred at 0°C and then gradually warmed up to 60°C and kept for 6 hours. After completion of the reaction, the mixture was cooled to room temperature and slowly poured into ice water to quench the reaction. The precipitated solid was collected by filtration and dried under vacuum to obtain the crude product. The crude product was purified by column chromatography using petroleum ether: ethyl acetate (85:15) as eluent to give 2.5 g (39.0% yield) of 1,3-dichloro-2-methoxy-5-nitrobenzene as an off-white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.22 (s, 2H), 4.01 (s, 3H).

References

[1] Patent: WO2017/117239, 2017, A1. Location in patent: Page/Page column 42
[2] Journal of Organic Chemistry, 1963, vol. 28, p. 1656 - 1662
[3] Bulletin of the Chemical Society of Japan, 1994, vol. 67, # 10, p. 2639 - 2646

3107-19-5
124-41-4
17742-69-7
Synthesis of 2,6-DICHLORO-4-NITROANISOLE from 3,5-Dichloro-4-fluoronitrobenzene and Sodium Methoxide
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View Lastest Price from 2,6-DICHLORO-4-NITROANISOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,6-DICHLORO-4-NITROANISOLE pictures 2019-12-24 2,6-DICHLORO-4-NITROANISOLE
17742-69-7
$1.00 1ASSAYS 98%min Career Henan Chemical Co
3,5-Dichloro-4-methoxynitrobenzene 1,3-Dichloro-2-Methoxy-5-Nitro 2,6-DICHLORO-4-NITROANISOLE 99% 2,6-DICHLORO-4-NITROANISOLE 1,3-DICHLORO-2-METHOXY-5-NITROBENZENE 1,3-DICHLORO-2-METHOXY-5-NITROBENZENE,99% Methyl-(2.6-dichlor-4-nitro-phenyl)-aether 3,5-Dichloro-4-methoxynitrobenzene, 2,6-Dichloro-4-nitrophenyl methyl ether, 1,3-Dichloro-2-methoxy-5-nitrobenzene NSC 212118 1,3-Dichloro-5-Methoxy-2-nitrobenzene 2.6-Dichlor-4-nitro-1-Methoxy-benzol 1,3-Dichloro-5-methoxy-2-nitrobenzene[3,5-Dichloro-4-nitroanisole] 4-Nitro-2,6-dichloroanisole 2,6-Dichloro-4-nitroanisole> Benzene, 1,3-dichloro-2-methoxy-5-nitro- 2,6-Dichloro-4-nitroanisole in isopropanol 2,6-Dichloro-4-nitroanisole, 98% 1,3-Dichloro-2-methoxy-5-nitrobenzene - [D94406] 17742-69-7 1742-69-7 Anisole Anisoles, Alkyloxy Compounds & Phenylacetates Chlorine Compounds Nitro Compounds
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