4-CHLORO-6-METHYLTHIOPYRIMIDINE
- CAS No.
- 89283-48-7
- Chemical Name:
- 4-CHLORO-6-METHYLTHIOPYRIMIDINE
- Synonyms
- 4-CHLORO-6-METHYLTHIOPYRIMIDINE;4-chloro-6-MethylpyriMidine-1-thiol;Pyrimidine, 4-chloro-6-(methylthio)-;4-Chloro-6-methylsulfanyl-pyrimidine;4-CHLORO-6-METHYLTHIOPYRIMIDINE ISO 9001:2015 REACH
- CBNumber:
- CB61215962
- Molecular Formula:
- C5H5ClN2S
- Molecular Weight:
- 160.62
- MDL Number:
- MFCD09870036
- MOL File:
- 89283-48-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Chloro-6-methylthiopyrimidine Aldrich | SYX00015 | 1g | $191 |
| 4-Chloro-6-methylthiopyrimidine 97% | OR960614 | 1g | $21 |
| 4-Chloro-6-methylthiopyrimidine 97% | OR960614 | 5g | $70 |
| 4-Chloro-6-methylthiopyrimidine 97% | OR960614 | 25g | $225 |
| 4-Chloro-6-methylthiopyrimidine 97% | OR960614 | 100g | $872 |
| Melting point | 50-51 °C |
|---|---|
| Boiling point | 260 ºC |
| Density | 1.37 |
| Flash point | 111 ºC |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | solid |
| pka | -1.50±0.17(Predicted) |
| Appearance | Light yellow to yellow Solid |
| InChI | 1S/C5H5ClN2S/c1-9-5-2-4(6)7-3-8-5/h2-3H,1H3 |
| InChIKey | BMQSAIGMUNXTKZ-UHFFFAOYSA-N |
| SMILES | CSc1cc(Cl)ncn1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
4-CHLORO-6-METHYLTHIOPYRIMIDINE price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SYX00015 | 4-Chloro-6-methylthiopyrimidine Aldrich | 89283-48-7 | 1g | $191 | 2026-04-30 | Buy |
| Apolloscientific | OR960614 | 4-Chloro-6-methylthiopyrimidine 97% | 89283-48-7 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR960614 | 4-Chloro-6-methylthiopyrimidine 97% | 89283-48-7 | 5g | $70 | 2026-06-04 | Buy |
| Apolloscientific | OR960614 | 4-Chloro-6-methylthiopyrimidine 97% | 89283-48-7 | 25g | $225 | 2026-06-04 | Buy |
| Apolloscientific | OR960614 | 4-Chloro-6-methylthiopyrimidine 97% | 89283-48-7 | 100g | $872 | 2026-06-04 | Buy |
4-CHLORO-6-METHYLTHIOPYRIMIDINE Chemical Properties,Uses,Production
Synthesis
1193-21-1
5188-07-8
89283-48-7
Example 12: Synthesis of 4-chloro-6-(methylthio)pyrimidine. 4,6-Dichloropyrimidine (15.4 g, 0.10 mol) was dissolved in THF (120 mL) at room temperature, followed by the addition of solid sodium methanethiol (NaSMe, 8.5 g, 0.12 mol). The reaction mixture was heated to 60 °C and maintained for 16 hours. After completion of the reaction, the mixture was cooled to room temperature and diluted with ethyl acetate (300 mL) and water (300 mL). The organic layer was separated, washed with brine, dried over anhydrous sodium sulfate and concentrated to give an orange colored oil. Recrystallization by hexane gave the light yellow solid product 4-chloro-6-(methylthio)pyrimidine (9.85 g, 0.061 mol, 61% yield).1H NMR (500 MHz, CDCl3) δ: 8.74 (s, 1H), 7.23 (s, 1H), 2.58 (s, 3H).
References
[1] Patent: WO2006/52913, 2006, A1. Location in patent: Page/Page column 236-237
[2] Patent: WO2008/77548, 2008, A1. Location in patent: Page/Page column 46
[3] Patent: WO2009/85913, 2009, A1. Location in patent: Page/Page column 64-65
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 23, p. 6529 - 6533
[5] Patent: WO2011/45353, 2011, A1. Location in patent: Page/Page column 42-43
4-CHLORO-6-METHYLTHIOPYRIMIDINE Preparation Products And Raw materials
4-CHLORO-6-METHYLTHIOPYRIMIDINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 +86-18019713315 | info@accelachem.com | United States | 21189 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29096 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49709 | 58 |
View Lastest Price from 4-CHLORO-6-METHYLTHIOPYRIMIDINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2025-11-18 | 4-CHLORO-6-METHYLTHIOPYRIMIDINE
89283-48-7
|
$1.10 | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-

- 4-CHLORO-6-METHYLTHIOPYRIMIDINE
89283-48-7
- $1.10
- 99.00%
- Dideu Industries Group Limited
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