ELOCALCITOL
- CAS No.
- 199798-84-0
- Chemical Name:
- ELOCALCITOL
- Synonyms
- BXL 628;Ro 26-9228;ELOCALCITOL;Ellocalciferol;(1R,3E,5S)-3-[(2E)-2-[(3aS,7aS)-1-[(E,2S)-6-ethyl-6-hydroxyoct-4-en-2-yl]-7a-methyl-3a,5,6,7-tetrahydro-3H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylidenecyclohexan-1-ol;Cyclohexanol, 3-[(2E)-2-[(3aS,7aS)-1-[(1S,3E)-5-ethyl-5-hydroxy-1-methyl-3-hepten-1-yl]-3,3a,5,6,7,7a-hexahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-5-fluoro-4-methylene-, (1R,3Z,5S)-
- CBNumber:
- CB61509111
- Molecular Formula:
- C29H43FO2
- Molecular Weight:
- 442.65
- MDL Number:
- MFCD09954119
- MOL File:
- 199798-84-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| BXL-628 ≥98% | 23129 | 1mg | $196 |
| BXL-628 ≥98% | 23129 | 5mg | $583 |
| BXL-628 ≥98% | 23129 | 1mg | $178 |
| Elocalcitol 99.15% | CS-0001526 | 1mg | $292 |
| Elocalcitol 99.15% | CS-0001526 | 1mg | $292 |
| More product size | |||
| Boiling point | 568.3±50.0 °C(Predicted) |
|---|---|
| Density | 1.05±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | Ethanol:20.0(Max Conc. mg/mL);45.18(Max Conc. mM) |
| form | A crystalline solid |
| pka | 14.04±0.40(Predicted) |
| color | White to off-white |
| optical activity | [α]/D +97 to +107°, c =c=1 in methanol |
| InChIKey | LRLWXBHFPGSUOX-GJQYOBCGSA-N |
| SMILES | F[C@H]1C[C@@H](C\C(=C\C=C2\[C@H]3[C@](CCC\2)(C(=CC3)[C@H](C\C=C\C(O)(CC)CC)C)C)\C1=C)O |
| FDA UNII | 2WDS5F2V6Q |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
ELOCALCITOL price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 23129 | BXL-628 ≥98% | 199798-84-0 | 1mg | $196 | 2026-04-30 | Buy |
| Cayman Chemical | 23129 | BXL-628 ≥98% | 199798-84-0 | 5mg | $583 | 2026-04-30 | Buy |
| Cayman Chemical | 23129 | BXL-628 ≥98% | 199798-84-0 | 1mg | $178 | 2024-03-01 | Buy |
| ChemScene | CS-0001526 | Elocalcitol 99.15% | 199798-84-0 | 1mg | $292 | 2026-06-04 | Buy |
| ChemScene | CS-0001526 | Elocalcitol 99.15% | 199798-84-0 | 1mg | $292 | 2026-06-04 | Buy |
ELOCALCITOL Chemical Properties,Uses,Production
Description
BXL-628 is an analog of vitamin D3 that has diverse biological activities. It increases death of androgen-stimulated human benign prostatic hyperplasia (BPH) cells via induction of apoptosis in a dose-dependent manner. In vivo, BXL-628 completely inhibits androgen-stimulated prostate overgrowth in a rat model of BPH. It reduces expression of IL-13 and IgE/mast cell-derived protease 1 (MMCP1) and decreases edema and leukocyte infiltration in the bladder wall in a mouse model of allergen-induced interstitial cystitis. BXL-628 also reduces the number of adherent endometrial stromal cells and decreases the total weight of endometrial lesions in a mouse model of endometriosis. Formulations containing BXL-628 are under clinical investigation for the treatment of BPH.
Uses
Elocalcitol (BXL-628) is a selective, orally active vitamin D receptor (VDR) agonist. Elocalcitol shows anti-inflammatory activity. Elocalcitol inhibits growth of prostate cancer cells[1][2].
References
[1] Mariani M, et al. The selective vitamin D receptor agonist, elocalcitol, reduces endometriosis development in a mouse model by inhibiting peritoneal inflammation. Hum Reprod. 2012 Jul;27(7):2010-9. DOI:10.1093/humrep/des150
[2] Marchiani S, et al. The vitamin D analogue BXL-628 inhibits growth factor-stimulated proliferation and invasion of DU145 prostate cancer cells. J Cancer Res Clin Oncol. 2006 Jun;132(6):408-16. DOI:10.1007/s00432-006-0086-8
ELOCALCITOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29807 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32468 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4017 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
| CR Corporation Limited | fred.wen@crcorporation.cn | China | 8645 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +86-18949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9984 | 58 |
View Lastest Price from ELOCALCITOL manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Elocalcitol
199798-84-0
|
$645.00-1880.00 | 10g | TargetMol Chemicals Inc. | |||
 |
2020-02-14 | ELOCALCITOL
199798-84-0
|
$7.00 | 1KG | 99% | 100KG | Career Henan Chemical Co |
-
- Elocalcitol
199798-84-0
- $645.00-1880.00
- TargetMol Chemicals Inc.
-
- ELOCALCITOL
199798-84-0
- $7.00
- 99%
- Career Henan Chemical Co
