(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
- CAS No.
- 101711-78-8
- Chemical Name:
- (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
- Synonyms
- 4-benzyl-3-propionyloxazolidin-2-one;(S)-4-BENZYL-3-PROPIONYL-2-OXAZOLIDINONE;-3-propionyL;(S)-N-Propionyl-4-benzyl-1;S-4-Benzyl-3-Propiony-2-Oxazolidinone;N-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE;N-3-PROPIONYL-(4S)-BENZYL-2-OXAZOLIDINONE;(4S)-4-Benzyl-3-propanoyloxazolidin-2-one;(S)-(+)-4-Benzyl-3-propiomyl-2-oxazolidin;(S)-(+)-4-BENZYL-3-PROPIONYL-2-OXALIDINONE
- CBNumber:
- CB6247465
- Molecular Formula:
- C13H15NO3
- Molecular Weight:
- 233.26
- MDL Number:
- MFCD00269688
- MOL File:
- 101711-78-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone 99% | 458775 | 5g | $131 |
| (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone >96.0%(GC) | B2166 | 1g | $43 |
| (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone >96.0%(GC) | B2166 | 5g | $124 |
| (S)-4-Benzyl-3-propionyl-2-oxazolidinone | TRC-B288650-5G | 5g | $249 |
| (S)-4-Benzyl-3-propionyl-2-oxazolidinone | TRC-B288650-2.5G | 2.5g | $193 |
| More product size | |||
| Melting point | 42-44 °C |
|---|---|
| Boiling point | 375.51°C (rough estimate) |
| alpha | 97 º (c=1, EtOH) |
| Density | 1.1475 (rough estimate) |
| refractive index | 103 ° (C=1, EtOH) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform, Methanol |
| form | Solid |
| pka | -2.35±0.40(Predicted) |
| color | Off-White to Pale Yellow |
| optical activity | [α]20/D +97°, c = 1 in ethanol |
| InChI | InChI=1S/C13H15NO3/c1-2-12(15)14-11(9-17-13(14)16)8-10-6-4-3-5-7-10/h3-7,11H,2,8-9H2,1H3/t11-/m0/s1 |
| InChIKey | WHOBYFHKONUTMW-NSHDSACASA-N |
| SMILES | O1C[C@H](CC2=CC=CC=C2)N(C(=O)CC)C1=O |
| CAS DataBase Reference | 101711-78-8(CAS DataBase Reference) |
| UNSPSC Code | 12352005 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302+H312+H332-H314 | |||||||||
| Precautionary statements | P501-P261-P270-P271-P264-P280-P362+P364-P303+P361+P353-P301+P330+P331-P301+P312+P330-P304+P340+P310-P305+P351+P338+P310-P405 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22-43 | |||||||||
| Safety Statements | 37/39-26-36-36/37 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29349990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone price More Price(92)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 458775 | (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone 99% | 101711-78-8 | 5g | $131 | 2026-04-30 | Buy |
| TCI Chemical | B2166 | (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone >96.0%(GC) | 101711-78-8 | 1g | $43 | 2026-04-30 | Buy |
| TCI Chemical | B2166 | (S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone >96.0%(GC) | 101711-78-8 | 5g | $124 | 2026-04-30 | Buy |
| TRC | TRC-B288650-5G | (S)-4-Benzyl-3-propionyl-2-oxazolidinone | 101711-78-8 | 5g | $249 | 2026-06-03 | Buy |
| TRC | TRC-B288650-2.5G | (S)-4-Benzyl-3-propionyl-2-oxazolidinone | 101711-78-8 | 2.5g | $193 | 2026-06-03 | Buy |
(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone Chemical Properties,Uses,Production
Chemical Properties
Colourless Solid
Uses
Intermediate in the preparation of Albaconazole.
Uses
Versatile chiral auxiliary for asymmetric synthesis.
Synthesis
90719-32-7
79-03-8
131685-53-5
Under nitrogen atmosphere, (S)-4-benzyl-2-azolidinone (800 mg, 4.5 mmol) was dissolved in a dry reaction vial of anhydrous tetrahydrofuran (30 mL) and cooled to -78 °C in a dry ice/acetone bath. A hexane solution of 1.6 M n-butyllithium (5.0 mmol, 3.1 mL) was added slowly and dropwise over 3 min. After stirring for 30 min, propionyl chloride (5.0 mmol, 0.43 mL) was added dropwise over 3 min. The reaction solution was slowly warmed to room temperature over 14 h. The reaction was subsequently quenched by the addition of saturated ammonium chloride solution (10 mL) and water (30 mL). The aqueous layer was extracted with ethyl acetate (3 x 40 mL), the organic phases were combined and dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to afford (R)-(-)-benzyl-3-propionyl-2-oxazolidinone (oil, 1.0 g, 96% yield) with >95% purity by HPLC.1H NMR (500 MHz, CDCl3): δ7.33 (dd, J1=7.4 Hz, J2=7.6 Hz, 2H), 7.29 (d, J=6.9 Hz, 1H), 7.21 (d, J=7.4 Hz, 2H), 4.67 (m, 1H), 4.18 (m, 2H), 3.31 (dd, J1=13.3 Hz, J2=3.2 Hz, 1H), 2.96 (m, 2H), 2.77 (dd, J1=13.3 Hz, J2=3.7 Hz, 1H), 1.21 (t, J=7.4 Hz, 3H).
References
[1] Chemistry - An Asian Journal, 2011, vol. 6, # 7, p. 1791 - 1799
[2] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 1, p. 144 - 148
[3] Journal of Organic Chemistry, 2008, vol. 73, # 8, p. 3292 - 3294
[4] Angewandte Chemie - International Edition, 2016, vol. 55, # 13, p. 4252 - 4255
[5] Angew. Chem., 2016, vol. 128, # 13, p. 4324 - 4327,4
(4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| RongNa Biotechnology Co.,Ltd | +86-86-13583358881 +8618560316533 | Brad@rongnabiotech.com | China | 3372 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1059@dideu.com | China | 29094 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 | info@afinechem.com | China | 15079 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 | dominicguo@gk-bio.com | CHINA | 9414 | 58 |
View Lastest Price from (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-25 | (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
101711-78-8
|
$10.00 | 1ASSAYS | 99% | 1 ton | RongNa Biotechnology Co.,Ltd | |
 |
2026-06-30 | (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
101711-78-8
|
1kg | 99% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-04-04 | (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
101711-78-8
|
1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. |
-
- (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
101711-78-8
- $10.00
- 99%
- RongNa Biotechnology Co.,Ltd
-
- (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
101711-78-8
- $0.00
- 99%
- Shaanxi Dideu New Materials Co. Ltd
-
- (4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone
101711-78-8
- 98%
- Henan Aochuang Chemical Co.,Ltd.
101711-78-8((4S)-(+)-4-Benzyl-3-propionyl-2-oxazolidinone)Related Search:
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