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ChemicalBook >> CAS DataBase List >>5-Amino-2-fluorophenol

5-Amino-2-fluorophenol

CAS No.
100367-48-4
Chemical Name:
5-Amino-2-fluorophenol
Synonyms
4-Fluoro-3-hydroxyaniline;5-Amino-2-fluorophenol;Phenol, 5-amino-2-fluoro-;5-Amino-2-fluorophenol,97%;5-Amino-2-fluorophenol 95+%;5-amino-2-fluorobenzenephenol;2-(1,1-dimethyl-2-hydroxyethyl)-1,3-dioxolane
CBNumber:
CB62527835
Molecular Formula:
C6H6FNO
Molecular Weight:
127.12
MDL Number:
MFCD13185335
MOL File:
100367-48-4.mol
MSDS File:
SDS
Last updated:2026-05-28 03:13:51
Product description Number Pack Size Price
5-Amino-2-fluorophenol ≥98% CS-0034100 1g $49
5-Amino-2-fluorophenol ≥98% CS-0034100 5g $168
5-Amino-2-fluorophenol ≥98% CS-0034100 250mg $4081
5-Amino-2-fluorophenol 95% PC8698 1g $71
5-Amino-2-fluorophenol ≥98% CS-0034100 1g $49

5-Amino-2-fluorophenol Properties

Melting point 156-158℃
Boiling point 255.3±20.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. 2-8°C, protect from light, stored under nitrogen
form Solid
pka 8.76±0.10(Predicted)
color White to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Skull and Crossbones (GHS06)
GHS06
Signal word  Warning
Hazard statements  H301-H315-H319-H335
Precautionary statements  P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
HazardClass  IRRITANT
HS Code  2922290090
NFPA 704
0
2 0

5-Amino-2-fluorophenol price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0034100 5-Amino-2-fluorophenol ≥98% 100367-48-4 1g $49 2026-06-04 Buy
ChemScene CS-0034100 5-Amino-2-fluorophenol ≥98% 100367-48-4 5g $168 2026-06-04 Buy
ChemScene CS-0034100 5-Amino-2-fluorophenol ≥98% 100367-48-4 250mg $4081 2026-06-04 Buy
Apolloscientific PC8698 5-Amino-2-fluorophenol 95% 100367-48-4 1g $71 2026-06-04 Buy
ChemScene CS-0034100 5-Amino-2-fluorophenol ≥98% 100367-48-4 1g $49 2026-06-04 Buy
Product number Packaging Price Buy
CS-0034100 1g $49 Buy
CS-0034100 5g $168 Buy
CS-0034100 250mg $4081 Buy
PC8698 1g $71 Buy
CS-0034100 1g $49 Buy

5-Amino-2-fluorophenol Chemical Properties,Uses,Production

Uses

5-Amino-2-fluorophenol is used as synthetic building block.

Synthesis

4-Fluoro-3-methoxyaniline

64465-53-8

5-Amino-2-fluorophenol

100367-48-4

Example 9A Step 1: 4-Fluoro-3-methoxyaniline (2.0 g, 14.2 mmol) was dissolved in dichloromethane (20 mL) at 0 °C and a dichloromethane solution of 1.0 M boron tribromide (40 mL) was slowly added dropwise. The reaction mixture was stirred at 0 °C, followed by gradual warming to room temperature and continued stirring overnight. Upon completion of the reaction, the reaction was quenched by the addition of methanol, followed by removal of the solvent under reduced pressure. Water was added to the residue, which was alkalized with saturated sodium bicarbonate solution to pH neutral and then extracted with ethyl acetate. The organic phase was washed with saturated brine, dried over anhydrous magnesium sulfate and concentrated under reduced pressure to give 5-amino-2-fluorophenol as a white solid (1.3 g, 73% yield). The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 9.26 (s, 1H), 6.81 (dd, 1H), 6.34 (dd, 1H), 6.04 (dd, 1H), 4.63 (br, 2H).

References

[1] Patent: WO2009/117080, 2009, A1. Location in patent: Page/Page column 171
[2] Patent: US2002/198194, 2002, A1
[3] Patent: WO2011/119704, 2011, A1. Location in patent: Page/Page column 45

5-Amino-2-fluorophenol Preparation Products And Raw materials

5-Amino-2-fluorophenol Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
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Henan Alfa Chemical Co., Ltd
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Zhengzhou Lingzhiyue Technology Co., Ltd
+86-0371-55074660 +86-13523716970 Lingzhiyue@aliyun.com China 3145 58

5-Amino-2-fluorophenol Spectrum

5-Amino-2-fluorophenol 95+% 5-Amino-2-fluorophenol 2-(1,1-dimethyl-2-hydroxyethyl)-1,3-dioxolane Phenol, 5-amino-2-fluoro- 5-Amino-2-fluorophenol,97% 5-amino-2-fluorobenzenephenol 4-Fluoro-3-hydroxyaniline 100367-48-4
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