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ChemicalBook >> CAS DataBase List >>BUTACAINE

BUTACAINE

CAS No.
149-16-6
Chemical Name:
BUTACAINE
Synonyms
Butyn;BUTACAINE;PHENBUTACAINE;Dibutylaminopropyl-p-aminobenzoate;p-Aminobenzoyldibutylaminopropanol;3-dibutylaminopropylp-aminobenzoate;3-Dibutylaminopropyl p-aminobenzoate;3-(Dibutylamino)propyl 4-aminobenzoate;3-(dibutylamino)propyl 4-azanylbenzoate;3-(dibutylamino)-1-propanolp-aminobenzoate
CBNumber:
CB6261717
Molecular Formula:
C18H30N2O2
Molecular Weight:
306.44
MDL Number:
MFCD00056117
MOL File:
149-16-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:06
Product description Number Pack Size Price
Butacaine 99.76% CS-4504 100mg $78
Butacaine >98% AA001L9K 100mg $115
Butacaine 98+% CD31003361 100mg $42
Butacaine 99.76% HY-B1007 100mg $84
Butacaine 99.76% HY-B1007 10mM*1mLinDMSO(Solution) $93
More product size

BUTACAINE Properties

Melting point 25°C
Boiling point bp0.11 178-182°
Density 1.0593 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. −20°C
solubility DMSO (Slightly), Methanol (Slightly)
pka pKa 8.96 (Uncertain)
form Solid
color White to Pale Orange
Stability Light Sensitive
EWG's Food Scores 1
FDA UNII Z84S23CGJJ
EPA Substance Registry System Butacaine (149-16-6)

SAFETY

Risk and Safety Statements

RIDADR  3249
WGK Germany  3
RTECS  UB0875000
HazardClass  6.1(b)
PackingGroup  III

BUTACAINE price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-4504 Butacaine 99.76% 149-16-6 100mg $78 2026-06-04 Buy
aablocks AA001L9K Butacaine >98% 149-16-6 100mg $115 2026-05-28 Buy
Crysdot CD31003361 Butacaine 98+% 149-16-6 100mg $42 2026-05-27 Buy
Arctom HY-B1007 Butacaine 99.76% 149-16-6 100mg $84 2026-05-26 Buy
Arctom HY-B1007 Butacaine 99.76% 149-16-6 10mM*1mLinDMSO(Solution) $93 2026-05-26 Buy
Product number Packaging Price Buy
CS-4504 100mg $78 Buy
AA001L9K 100mg $115 Buy
CD31003361 100mg $42 Buy
HY-B1007 100mg $84 Buy
HY-B1007 10mM*1mLinDMSO(Solution) $93 Buy

BUTACAINE Chemical Properties,Uses,Production

Originator

Butelline,ALK-Abello

Uses

radioopaque agent

Uses

Butacaine is an human glutathione transferase P1-1 (GST P1-1).

Definition

ChEBI: 4-aminobenzoic acid 3-(dibutylamino)propyl ester is a benzoate ester.

Manufacturing Process

40 g p-nitro-gamma-bromo-propylbenzoate and 40 g dibutylamine are heated together at 60°C, for four hours. The excess dibutyl amine is removed by washing the product with water and then steam distilling the residue. The material remaining in the flask is taken up in benzene and treated with aqueous hydrochloric acid. Part of the p-nitrobenzoyl-gamma-di-nbutylamminopropanol hydrochloride thus formed goes into the water layer, while most of it separates as a heavy oily layer. This, together with the water layer, is separated from the benzene layer, made alkaline, and the resulting base taken up in benzene. Upon removal of the solvent, the desired pnitrobenzoyl- gamma-di-n-butylamminopropanol is obtained.
The p-nitrobenzoyl-gamma-di-n-butylamminopropanol is reduced by warming to about 60°C with an excess of iron filings and a small amount of hydrochloric acid for four hours. The material is then allowed to cool, neutralized with dilute sodium hydroxide solution, and extracted with ether. Upon the removal of the ether, the free base, para-aminobenzoyl-gamma-din- butylaminopropanol, remains behind as an oil. It is exactly neutralized with aqueous hydrochloric acid and the resulting solid salt purified by recrystallization from water or a suitable organic solvent. It melts at 151°- 152°C (corr.) after drying at 100°C.

brand name

Butyn (Abbott).

Therapeutic Function

Local anesthetic

BUTACAINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate 1-Propanol, 3-(dibutylamino)-, 4-aminobenzoate (ester) 1-Propanol, 3-(dibutylamino)-, p-aminobenzoate 1-Propanol, 3-(dibutylamino)-, p-aminobenzoate (ester) 3-(Dibutyamino)-1-propanol-p-aminobenzoate (ester) 3-(dibutylamino)-1-propano4-aminobenzoate(ester) 3-(Dibutylamino)-1-propanol p-aminobenzoate 3-(dibutylamino)-1-propanolp-aminobenzoate 3-(dibutylamino)-1-propanop-aminobenzoate(ester) 3-(Dibutylamino)propyl 4-aminobenzoate 3-(p-Aminobenzoxy)-1-di-n-butylaminopropane 3-Dibutylaminopropyl p-aminobenzoate Dibutylaminopropyl-p-aminobenzoate PHENBUTACAINE 4-Aminobenzoic acid 3-(dibutylamino)propyl 4-Aminobenzoic acid 3-(dibutylamino)propyl ester 3-(dibutylamino)propyl 4-azanylbenzoate 3-dibutylaminopropylp-aminobenzoate p-Aminobenzoyldibutylaminopropanol BUTACAINE 1-Propanol, 3-(dibutylamino)-, 1-(4-aminobenzoate) Butyn 149-16-6 Analytical Standards Alphabetic Analytical Chromatography Product Catalog BI - BZ TELEPAQUE
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