360 A
- CAS No.
- 794458-56-3
- Chemical Name:
- 360 A
- Synonyms
- 360A;360 A;360A;360 A;360A,Telomerase,inhibit,Inhibitor,G-quadruplex;3,3'-[2,6-Pyridinediylbis(carbonylimino)]bis[1-methylquinolinium]
- CBNumber:
- CB62666581
- Molecular Formula:
- C27H23N5O2+2
- Molecular Weight:
- 449.50382
- MDL Number:
- MFCD26142927
- MOL File:
- 794458-56-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 360A 97% | CS-1440 | 1mg | $130 |
| 360A 97% | CS-1440 | 5mg | $298 |
| 360A | A3119 | 5mg | $299 |
| 360A | A3119 | 10mg | $479 |
| 360A | A3119 | 50mg | $1295 |
| More product size | |||
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
360 A price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-1440 | 360A 97% | 794458-56-3 | 1mg | $130 | 2026-06-04 | Buy |
| ChemScene | CS-1440 | 360A 97% | 794458-56-3 | 5mg | $298 | 2026-06-04 | Buy |
| ApexBio Technology | A3119 | 360A | 794458-56-3 | 5mg | $299 | 2026-05-06 | Buy |
| ApexBio Technology | A3119 | 360A | 794458-56-3 | 10mg | $479 | 2026-05-06 | Buy |
| ApexBio Technology | A3119 | 360A | 794458-56-3 | 50mg | $1295 | 2026-05-06 | Buy |
360 A Chemical Properties,Uses,Production
Uses
360A is a selective stabilizer of G-quadruplex, and also inhibits telomerase activity with an IC50 of 300 nM for telomerase in TRAP-G4 assay.
References
[1] Pennarun G, et al. Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands. Oncogene. 2005 Apr 21;24(18):2917-28. DOI:10.1038/sj.onc.1208468
[2] Gauthier LR, et al. Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. Cell Mol Life Sci. 2012 Feb;69(4):629-40. DOI:10.1007/s00018-011-0767-6
360 A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19853 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39037 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131956 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6002 | 61 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9891 | 58 | |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29974 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4861 | 58 |
