(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
- CAS No.
- 102191-92-4
- Chemical Name:
- (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
- Synonyms
- 2-(tert-butyldimethylsilyloxy)acetaldehyde;(tert-Butyl-dimethyl-silanyloxy)-acetaldehyde;DK447;oxy)acetaL;DKFELEX0096;T-BUTYLDIMETHYLSILOXYACETALDEHYDE;T-BUTYLDIMETHYLSILYLOXYACETALDEHYDE;t-BUTYLDIMETHYLSILOXYACETALDEHYDE,90%;DIMETHYL-TERT-BUTYLSILYLOXYACETALDEHYDE;(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
- CBNumber:
- CB6436993
- Molecular Formula:
- C8H18O2Si
- Molecular Weight:
- 174.31
- MDL Number:
- MFCD01321229
- MOL File:
- 102191-92-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (tert-Butyldimethylsilyloxy)acetaldehyde 90% | 449458 | 1g | $146 |
| (tert-Butyldimethylsilyloxy)acetaldehyde 90% | 449458 | 5g | $400 |
| 2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 % | B6269 | 1G | $71 |
| 2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 % | B6269 | 5G | $216 |
| (tert-?Butyldimethylsilylox?y)?acetaldehyde | TRC-B942745-500MG | 500mg | $78 |
| More product size | |||
| Melting point | 165-167 ºC |
|---|---|
| Boiling point | 165-167 °C(lit.) |
| Density | 0.915 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 140 °F |
| storage temp. | 2-8°C |
| form | Powder |
| color | White to light beige to grey |
| Specific Gravity | 0.915 |
| Hydrolytic Sensitivity | 8: reacts rapidly with moisture, water, protic solvents |
| InChI | InChI=1S/C8H18O2Si/c1-8(2,3)11(4,5)10-7-6-9/h6H,7H2,1-5H3 |
| InChIKey | MEBFFOKESLAUSJ-UHFFFAOYSA-N |
| SMILES | C(=O)CO[Si](C(C)(C)C)(C)C |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H226-H315-H319-H335 |
| Precautionary statements | P210-P233-P240-P241-P303+P361+P353-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN 1989 3/PG 3 |
| WGK Germany | 3 |
| TSCA | No |
| HazardClass | 3 |
| HS Code | 29319090 |
| Storage Class | 3 - Flammable liquids |
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 3 Skin Irrit. 2 STOT SE 3 |
| Limited Quantities | 5.0 L (1.3 gallons) (liquid) |
| Excepted Quantities | Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L) |
(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE price More Price(54)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 449458 | (tert-Butyldimethylsilyloxy)acetaldehyde 90% | 102191-92-4 | 1g | $146 | 2026-04-30 | Buy |
| Sigma-Aldrich | 449458 | (tert-Butyldimethylsilyloxy)acetaldehyde 90% | 102191-92-4 | 5g | $400 | 2026-04-30 | Buy |
| TCI Chemical | B6269 | 2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 % | 102191-92-4 | 1G | $71 | 2026-04-30 | Buy |
| TCI Chemical | B6269 | 2-[(tert-Butyldimethylsilyl)oxy]acetaldehyde min. 95.0 % | 102191-92-4 | 5G | $216 | 2026-04-30 | Buy |
| TRC | TRC-B942745-500MG | (tert-?Butyldimethylsilylox?y)?acetaldehyde | 102191-92-4 | 500mg | $78 | 2026-06-03 | Buy |
(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Chemical Properties,Uses,Production
Chemical Properties
Clear colorless to straw colored liquid
Uses
Employed in the construction of the key tetrahydropyran subunit in a recent synthesis of the marine natural product (–)-dactylodide.
Synthesis
102229-10-7
102191-92-4
Oxalyl chloride (13.7 mL, 162.2 mmol) was dissolved in anhydrous dichloromethane (400 mL) under nitrogen protection and cooled to -78°C. Dimethyl sulfoxide (25.1 mL, 353.9 mmol) was added slowly and stirred for 30 minutes. Subsequently, a solution of 2-((tert-butyldimethylsilyl)oxy)ethanol (26.0 g, 147.5 mmol) in anhydrous dichloromethane (100 mL) was added dropwise. After maintaining -78 °C and continuing to stir for 30 min, triethylamine (102.74 mL, 737.0 mmol) was added slowly and dropwise. The reaction mixture was stirred at -78 °C for another 30 min, then gradually warmed up to room temperature and continued stirring for 1 h. The reaction mixture was then stirred at -78 °C for 1 h. The reaction mixture was then gradually warmed up to room temperature. The pH of the reaction mixture was adjusted to 4 with aqueous 2N hydrochloric acid and then extracted with dichloromethane (3 x 400 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give 2-((tert-butyldimethylsilyl)oxy)acetaldehyde (34.0 g, 100%) as a colorless oil. The product can be used directly in the subsequent reaction without further purification.
References
[1] Organic Letters, 2016, vol. 18, # 18, p. 4534 - 4537
[2] Patent: WO2017/24018, 2017, A1. Location in patent: Paragraph 00132
[3] Patent: US2016/122345, 2016, A1. Location in patent: Paragraph 0115; 0118
[4] Patent: US9481674, 2016, B1. Location in patent: Page/Page column 47; 48
[5] Patent: WO2017/87608, 2017, A1. Location in patent: Paragraph 00125; 00128
(TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 14026 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49979 | 58 | |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29792 | 58 |
| Hubei Co-Formula Material Tech Co., Ltd. | +86-27-84459282 | sales@cfmats.com | CHINA | 882 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14303 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52704 | 58 |
View Lastest Price from (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-02 | (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
102191-92-4
|
1KG | 98% | 1000KG /month | Shanghai Daken Advanced Materials Co.,Ltd | ||
 |
2021-07-02 | (tert-Butyldimethylsilyloxy)acetaldehyde
102191-92-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2019-12-27 | (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
102191-92-4
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
102191-92-4
- $0.00
- 98%
- Shanghai Daken Advanced Materials Co.,Ltd
-
- (tert-Butyldimethylsilyloxy)acetaldehyde
102191-92-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- (TERT-BUTYLDIMETHYLSILYLOXY)ACETALDEHYDE
102191-92-4
- $1.00
- 99%
- Career Henan Chemical Co
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