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Moesin (Q480) Antibody

CAS No.
Chemical Name:
Moesin (Q480) Antibody
Synonyms
Moesin (Q480) Antibody
CBNumber:
CB65655900
Molecular Formula:
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

Moesin (Q480) Antibody Chemical Properties,Uses,Production

Source

Rabbit

Reactivity

Human;Mouse;Rat;Bovine

Background

The ezrin, radixin, and moesin proteins function as linkers between the plasma membrane and the actin cytoskeleton and are involved in cell adhesion, membrane ruffling, and microvilli formation. ERM proteins undergo intra or intermolecular interaction between their amino- and carboxy-terminal domains, existing as inactive cytosolic monomers or dimers. Phosphorylation at a carboxy-terminal threonine residue disrupts the amino- and carboxy-terminal association and may play a key role in regulating ERM protein conformation and function. Phosphorylation at Thr567 of ezrin is required for cytoskeletal rearrangements and oncogene-induced transformation. Ezrin is also phosphorylated at tyrosine residues upon growth factor stimulation. Phosphorylation of Tyr353 of ezrin transmits a survival signal during epithelial differentiation.

References

[1] Tsukita, S. and Yonemura, S. (1999) J Biol Chem 274, 34507-10.
[2] Mangeat, P. et al. (1999) Trends Cell Biol 9, 187-92.
[3] Matsui, T. et al. (1998) J Cell Biol 140, 647-57.
[4] Gautreau, A. et al. (2000) J Cell Biol 150, 193-203.
[5] Tran Quang, C. et al. (2000) EMBO J 19, 4565-76.
[6] Gautreau, A. et al. (1999) Proc Natl Acad Sci U S A 96, 7300-5.

Moesin (Q480) Antibody Preparation Products And Raw materials

Raw materials

Preparation Products

Moesin (Q480) Antibody Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
Cell Signaling Technology Inc 21-80243558 86218024 info@cellsignal.cn China 6427 58
Guangzhou Bingheng Biotechnology Co., Ltd. 13631342304 CHINA 6888 58
Beijing Boning Biotechnology Co., Ltd. 010-67500625 18210120938 384669408@qq.com China 6395 58
Moesin (Q480) Antibody
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